Patents by Inventor K. Grant Taylor

K. Grant Taylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bone-selective osteogenic oxysterol-bone targeting agents
    Patent number: 9683009
    Abstract: Compounds and compositions for the treatment of bone disorders are presented.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: June 20, 2017
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Farhad Parhami, Frank Stappenbeck, Michael E. Jung, William M. Pierce, Jr., Kevyn Merten, K. Grant Taylor
  • NOVEL OXYSTEROL ANALOGUE, OXY149, INDUCES OSTEOGENESIS AND HEDGEHOG SIGNALING AND INHIBITS ADIPOGENESIS
    Publication number: 20150140059
    Abstract: This invention relates, e.g., to a synthetic compound, Oxy149, having the structure (Formula I) or a bioactive or pharmaceutical composition comprising Oxy149 and a pharmaceutically acceptable carrier. Methods are also disclosed for using the compound or bioactive or pharmaceutical composition to treat a variety of disorders, including e.g. bone disorders, obesity, cardiovascular disorders, and neurological disorders. Oxy149 can be delivered either locally or systemically.
    Type: Application
    Filed: March 15, 2013
    Publication date: May 21, 2015
    Inventors: Farhad Parhami, Michael Jung, Frank Stappenbeck, William Pierce, K. Grant Taylor, Kevyn E. Merten
  • METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH
    Publication number: 20130029901
    Abstract: Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; and a Linking Portion (RL) connecting the Bone Targeting Portion and the Bone Active Portion.
    Type: Application
    Filed: July 30, 2012
    Publication date: January 31, 2013
    Inventors: William M. PIERCE, JR., K. Grant TAYLOR, Leonard C. WAITE, Kevyn MERTEN
  • METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH
    Publication number: 20120083440
    Abstract: Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; and a Linking Portion (RL) connecting the Bone Targeting Portion and the Bone Active Portion.
    Type: Application
    Filed: October 5, 2011
    Publication date: April 5, 2012
    Inventors: William M. Pierce, JR., K. Grant Taylor, Leonard C. Waite, Kevyn Merten
  • Methods and compounds for the targeted delivery of agents to bone for interaction therewith
    Patent number: 8071575
    Abstract: Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; and a Linking Portion (RL) connecting the Bone Targeting Portion and the Bone Active Portion.
    Type: Grant
    Filed: February 22, 2008
    Date of Patent: December 6, 2011
    Assignee: University of Louisville Research Foundation
    Inventors: William M. Pierce, Jr., K. Grant Taylor, Leonard C. Waite
  • METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH
    Publication number: 20090118164
    Abstract: Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; and a Linking Portion (RL) connecting the Bone Targeting Portion and the Bone Active Portion.
    Type: Application
    Filed: February 22, 2008
    Publication date: May 7, 2009
    Inventors: William M. Pierce, JR., K. Grant Taylor, Leonard C. Waite
  • METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH
    Publication number: 20080221070
    Abstract: Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting bone; a Linking Portion (RL) connecting the Bone Targeting Portion and the Bone Active Portion. The Bone Active Portion is derived from an estrogenic agent. Compounds can also include a Blocking Group (RP) that reduces or eliminates the estrogenic activity of the Bone Active Portion.
    Type: Application
    Filed: March 6, 2008
    Publication date: September 11, 2008
    Inventors: William M. Pierce, K. Grant Taylor, Leonard C. Waite
  • Bone targeting compounds for delivering agents to bone for interaction therewith
    Patent number: 7399789
    Abstract: The present invention relates to compounds of the formula or pharmaceutically acceptable salts thereof, useful for delivering agents having the capacity to diagnose, treat or prevent bone injury or disease to the bone for interaction therewith.
    Type: Grant
    Filed: February 14, 2007
    Date of Patent: July 15, 2008
    Assignee: University of Louisville Research Foundation
    Inventors: William M. Pierce, Leonard C. Waite, K. Grant Taylor
  • BONE TARGETING COMPOUNDS FOR DELIVERING AGENTS TO BONE FOR INTERACTION THEREWITH
    Publication number: 20070161710
    Abstract: The present invention relates to compounds of the formula or pharmaceutically acceptable salts thereof, useful for delivering agents having the capacity to diagnose, treat or prevent bone injury or disease to the bone for interaction therewith.
    Type: Application
    Filed: February 14, 2007
    Publication date: July 12, 2007
    Inventors: William Pierce, Leonard Waite, K. Grant Taylor
  • Bone targeting compounds for delivering agents to the bone for interaction therewith
    Patent number: 7196220
    Abstract: The present invention relates to compounds of the formula or pharmaceutically acceptable salts thereof, useful for delivering agents having the capacity to diagnose, treat or prevent bone injury or disease to the bone for interaction therewith.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: March 27, 2007
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: William M. Pierce, Jr., Leonard C. Waite, K. Grant Taylor