Abstract: A method of fabricating radiation sensor dies includes forming a plurality of radiation-sensitive detector elements and a plurality of visible identifiers on at least some of the radiation-sensitive detector elements on a substrate, where each visible identifier is located in a different sub-region of the substrate containing a subset of the radiation-sensitive detector elements, and separating the sub-regions of the substrate from one another to provide a plurality of radiation sensor dies, where the visible identifier on each radiation sensor die uniquely identifies the radiation sensor die with respect to the other radiation sensor dies of the plurality of radiation sensor dies.

Abstract: This invention provides compositions for controlled localized depositing of one or more drugs within a subject. More particularly, described herein are compositions comprising a) a polyethylene glycol (PEG) composition having a first low molecular weight PEG (Mw between 200-500 Da) and a second low molecular weight PEG (Mw between 500-2000 Da) and b) a mucoadhesive in polymer. Alternatively, composition may comprise a) a polyethylene glycol (PEG) composition having a first low molecular weight PEG (Mw between 200-500 Da) and a second low molecular weight PEG (Mw between 500-2000 Da), b) a water insoluble polymer and c) a mucoadhesive polymer. Furthermore, the composition may further comprise one or more drugs. Also provided are methods of manufacturing and administering the compositions described herein, which are used as biodegradable, injectable mucoadhesive low-viscosity pastes.

Abstract: A system may include: a server comprising a rule cache; a user device communicably coupled to the server; a computer-readable medium comprising instructions that cause the server to: monitor a plurality of third-party data sources; obtain, via a queueing service, a plurality of pieces of content from the plurality of third-party data sources; for each piece of content, fetch a rule ID from a list of rule IDs on the user device, wherein the rule ID is fetched based on the content and a pre-selected setting on the user device; use the rule ID to fetch a rule from the rule cache, the rule comprising a script, the script comprising executable code; execute the script on the piece of content to determine if the piece of content matches the rule; and in response to determining that the piece of content matches the rule, send an alert to the user device.

Abstract: The present invention relates to compositions and methods to provide continuous and controlled release of therapeutic agent(s) during a procedure such as an interventional vascular procedure, e.g., to reduce acute and chronic complications and improve outcomes.

Abstract: Various aspects of the present disclosure provide compositions including a water-insoluble therapeutic agent and a gallate-containing compound. Other aspects provide methods of using such compositions.

Abstract: A radiation sensor includes a radiation-sensitive semiconductor layer, a cathode electrode disposed over a front side of the radiation-sensitive semiconductor layer that is configured to be exposed to radiation, at least one anode electrode disposed over a backside of the radiation-sensitive semiconductor layer, and a potential barrier layer located between the cathode electrode and the front side of the radiation-sensitive semiconductor layer.

Abstract: This invention provides compositions for controlled localized release of one or more drugs within a subject. More particularly, described herein are compositions comprising a hydrophobic water-insoluble polymer, a low molecular weight biocompatible glycol, and one or more drugs. The compositions described herein may also optionally include a di-block copolymer and/or a swelling agent.

Abstract: The present invention relates to compositions and methods to provide continuous and controlled release of therapeutic agent(s) during a procedure such as an interventional vascular procedure, e.g., to reduce acute and chronic complications and improve outcomes.

Abstract: A radiation sensor includes a radiation-sensitive semiconductor layer, a cathode electrode disposed over a front side of the radiation-sensitive semiconductor layer that is configured to be exposed to radiation, at least one anode electrode disposed over a backside of the radiation-sensitive semiconductor layer, and a potential barrier layer located between the cathode electrode and the front side of the radiation-sensitive semiconductor layer.

Abstract: A thermal stabilization vessel may include a double walled tube. The tube may have an outer wall, an inner wall, and a sealed off volume located between the inner and outer walls. A removable base may close off a bottom opening of the tube and conduct heat to or from a container placed within the vessel. A top may partially close off a top opening of the tube. The top may include an annulus of elastomeric material. The annulus may have a plurality of resilient tabs extending radially inward toward a central axis of the tube. When a container such as a bottle of wine is placed within a vessel, the tabs of the annulus may resiliently deflect as needed to accommodate the container and then restrict air exchange between an ambient environment and a space located interior to the inner wall of the tube and exterior to the container.

Abstract: A radiation detector tile includes a single crystal compound semiconductor tile having a zinc blende crystal structure, a (111) plane first major (i.e. prominent) surface and four side surfaces which are rotated by an angle of 13° to 17° to a {110} family of planes. The tile may be formed by dicing a (111) oriented wafer at directions which are rotated by an angle of 13° to 17° from <110> in-plane slipping directions to reduce or eliminate the side surface chipping and sub surface dislocation defects.

Abstract: Various aspects of the present disclosure provide compositions including a water-insoluble therapeutic agent and a gallate-containing compound. Other aspects provide methods of using such compositions.

Abstract: A system may include: a server comprising a rule cache; a user device communicably coupled to the server; a computer-readable medium comprising instructions that cause the server to: monitor a plurality of third-party data sources; obtain, via a queueing service, a plurality of pieces of content from the plurality of third-party data sources; for each piece of content, fetch a rule ID from a list of rule IDs on the user device, wherein the rule ID is fetched based on the content and a pre-selected setting on the user device; use the rule ID to fetch a rule from the rule cache, the rule comprising a script, the script comprising executable code; execute the script on the piece of content to determine if the piece of content matches the rule; and in response to determining that the piece of content matches the rule, send an alert to the user device.

Abstract: This invention provides compositions for controlled localized release of one or more drugs within a subject. More particularly, described herein are compositions comprising a hydrophobic water-insoluble polymer, a low molecular weight biocompatible glycol, and one or more drugs. The compositions described herein may also optionally include a di-block copolymer and/or a swelling agent.

Abstract: A radiation detector includes a semiconductor layer having opposing first and second surfaces, anodes disposed over the first surface of the semiconductor layer in a pixel pattern, a cathode disposed over the second surface of the semiconductor layer, and an electrically conductive pattern disposed over the first surface of the semiconductor layer in interpixel gaps between the anodes. At least a portion of the electrically conductive pattern is not electrically connected to an external bias source.

Abstract: A thermal stabilization vessel may include a double walled tube. The tube may have an outer wall, an inner wall, and a sealed off volume located between the inner and outer walls. A removable base may close off a bottom opening of the tube and conduct heat to or from a container placed within the vessel. A top may partially close off a top opening of the tube. The top may include an annulus of elastomeric material. The annulus may have a plurality of resilient tabs extending radially inward toward a central axis of the tube. When a container such as a bottle of wine is placed within a vessel, the tabs of the annulus may resiliently deflect as needed to accommodate the container and then restrict air exchange between an ambient environment and a space located interior to the inner wall of the tube and exterior to the container.

Abstract: PNPase inhibitors (such as 8-substituted guanine and/or 8-substituted guanosine) and/or PNPase purine nucleoside substrates (such as guanosine and/or inosine) can also be used in methods of treating SCD or reducing sickling of red blood cells (RBCs). Herein, 8-substituted guanine and/or 8-substituted guanosine compounds are used in methods to treat hypertension (such as systemic or pulmonary hypertension), stroke, diabetes, and/or patients in need of a diuretic. In addition, 8-substituted guanine and/or 8-substituted guanosine compounds are included in a beverage composition. Further, purine nucleoside phosphorylase (PNPase) inhibitors (such as 8-substituted guanine and/or 8-substituted guanosine) and/or PNPase purine nucleoside substrates (such as guanosine and/or inosine) can be used in methods of treating or reducing the risk of pulmonary hypertension (PH), such as PH associated with HIV or sickle cell disease (SCD).

Abstract: A method in a communication device equipped with an electronic circuit includes obtaining a geographic location of a vehicle in which the communication device operates; monitoring at least one sensor signal that corresponds to road quality; determining a road quality indication of the geographic location based on the at least one sensor signal; transmitting the geographic location and the road quality indication to a server; and determining, using an information received from the server, whether the road quality indication differs from an average road quality indicia for the geographic location.

Abstract: A combination of a fluid dispenser and a table includes the table having a top surface and a bottom surface; the fluid dispenser having a base with a base top surface and a base bottom surface, the base top surface to secure flat against the bottom surface of the table, the base further having a first rail extending at least a partial length of the first side and a second rail extending at least a partial length of the second side; a body forming an interior area, the body having a first lip and a second lip to slidingly engage with the first rail and the second rail, thereby securing the base and the body together; a pump in communication with the interior area; a button engaged with the pump; and an opening extending into the interior area.