Patents by Inventor Károly Kánai

Károly Kánai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluoropyrrolidines having dipeptidyl peptidase enzyme inhibitory activity
    Patent number: 8063045
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: November 22, 2011
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • FLUOROPYRROLIDINES HAVING DIPEPTIDYL PEPTIDASE ENZYME INHIBITORY ACTIVITY
    Publication number: 20100210838
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Application
    Filed: February 1, 2010
    Publication date: August 19, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Peter Arányi, László Balázs, Imre Bata, Sándor Bátori, Éva Boronkay, Philippe Bovy, Károly Kánai, Zoltán Kapui, Edit Susán, Tibor Szabó, Lajos T. Nagy, Katalin Urbán-Szabó, Márton Varga
  • Fluoropyrrolidines having dipeptidyl peptidase enzyme inhibitory activity
    Patent number: 7655663
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: February 2, 2010
    Assignee: sanofi-aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • FLUOROPYRROLIDINES HAVING DIPEPTIDYL PEPTIDASE ENZYME INHIBITORY ACTIVITY
    Publication number: 20080161310
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Application
    Filed: March 5, 2008
    Publication date: July 3, 2008
    Applicant: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • Compounds
    Patent number: 7348327
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Grant
    Filed: March 4, 2003
    Date of Patent: March 25, 2008
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • Compounds
    Publication number: 20050130981
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Application
    Filed: March 4, 2003
    Publication date: June 16, 2005
    Inventors: Peter Aranyl, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos Nagy, Katalin Urban-Szabo, Marton Varga
  • Prolylendopeptidase inhibitors
    Patent number: 6191161
    Abstract: The present invention relates to new prolylendopeptidase inhibitors of general formula (I).
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: February 20, 2001
    Assignee: Chinoin Gyogyszer es Vegyeszeti
    Inventors: Károly Kánai, Sándor Erdö, Andrea Szappanos, Judit Bence, István Hermecz, Györgyné Szvoboda, Sándor Bátori, Gergely Héja, Mariá Balogh, Ágnes Horváth, Judit Sipos, Bodor Veronika Bártáne, Zsolt Párkányi, Viktor Lakics, Péter Molnár
  • 7-oxo-PGI.sub.2 -ephedrine salts and their pharmaceutical compositions and methods
    Patent number: 4735965
    Abstract: The invention relates to new 7-oxo-PGI.sub.2 -ephedrine salt analogues of the Formula I ##STR1## wherein A stands for --(CH.sub.2).sub.2 --, cis or trans --CH.dbd.CH-- or --C.tbd.C--;R.sup.1 is lower alkyl or hydrogen;B represents a chemical bond, --CH.sub.2 -- or --CR.sup.2 R.sup.3 ;R.sup.2 stands for lower alkyl or hydrogen;R.sup.3 represents lower alkyl or hydrogen;X is a chemical bond, --O-- or --CH.sub.2 --;R.sup.4 stands for C.sub.1-6 alkyl, C.sub.4-7 cycloalkyl, C.sub.1-6 fluoroalkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, phenyl, substituted phenyl or heteroaryl.The salts of the Formula I show the same pharmacological profile as the sodium salt of PGI.sub.2, they inhibit blood aggregation and the secretion of gastric acid, are useful in the prevention of anginal attacks.
    Type: Grant
    Filed: May 28, 1986
    Date of Patent: April 5, 1988
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Gabor Kovacs, Geza Galambos, Istvan Tomoskozi, Karoly Kanai, Peter Gyory, Peter Kormoczy, Istvan Stadler, Laszlo Szekeres, Gyula Papp, Eva Udvary, Pal Hadhazy, Jeno Marton, Gyorgy Dorman
  • Preparation of 6-keto-7-oxo-PGF.sub.1.alpha. -derivatives
    Patent number: 4429123
    Abstract: The present invention relates to a process for the preparation of compounds of the general Formula I ##STR1## (wherein A is a straight or branched chain alkylene group having 1-5 carbon atoms;B is ethylene, Z or E vinylene, or ethynylene;R.sup.1 stands for hydrogen, an alkyl group having 1-5 carbon atoms or a pharmaceutically acceptable cation;R.sup.2 is hydrogen, an alkanoyl group having 1-5 carbon atoms or aroyl;R.sup.3 is hydrogen or methyl;R.sup.4 is a straight or branched chain alkyl group having 1-8 carbon atoms or an optionally monosubstituted aryloxymethyl group;R.sup.5 stands for hydrogen or an alkyl group having 1-5 carbon atoms)which comprises oxidizing a compound of the Formula III, IV or V ##STR2## or a mixture thereof R.sup.6 is hydrogen or an alkyl or alkanoyl group having 1-5 carbon atoms with a mild electrophilic oxidizing agent and if desired reacting the compound of the Formula I thus obtained wherein R.sup.
    Type: Grant
    Filed: April 13, 1982
    Date of Patent: January 31, 1984
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Istvan Tomoskozi, Istvan Szekely, Karoly Kanai, Peter Gyori, Gabor Kovacs