Abstract: The invention provides a method and clinical data mining system for enabling a user to derive knowledge from data corresponding to a plurality of electronic health records stored in a repository. One or more data elements are provided as an input. The data elements may include textual reports, images, and one or more criteria specified by the user. Information is extracted from one or more images associated with one or more electronic health records stored in the repository, based on the data elements. Further, information is extracted from one or more textual reports and structured data associated with the one or more electronic health records. Thereafter, one or more reports are generated based on the extracted information to enable the user to analyze the information. Subsequently, the user may derive knowledge from the data based on the analysis.