Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: Various embodiments of layout tool devices and systems are provided. In various embodiments, the layout tool devices and systems improve layout work flow using layout tools, such as via using lasers and/or customized flexible elongate structures to facilitate marking points along a line, including systems with multiple devices, such as mobile devices, that emit lasers in combination with the other devices in the system.

Abstract: The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to amplified epidermal growth factor receptor (EGFR) and to the de2-7 EGFR truncation of the EGFR. In particular, the epitope recognized by the specific binding members, particularly antibodies and fragments thereof, is enhanced or evident upon aberrant post-translational modification. These specific binding members are useful in the diagnosis and treatment of cancer. The binding members of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof.

Abstract: Some embodiments described in this disclosure are directed to one or more electronic devices that facilitate control of playback of a live content item displayed in a playback user interface. Some embodiments described in this disclosure are directed to one or more electronic devices that facilitate display of key content corresponding to a live content item in a key content user interface. Some embodiments described in this disclosure are directed to one or more electronic devices that facilitate concurrently display of multiple content items in a Multiview user interface. Some embodiments described in this disclosure are directed to one or more electronic devices that facilitate display of insights corresponding to a content item displayed in a playback user interface.

Abstract: A surgical patient support includes a foundation frame, a support top, and a brake system. The foundation frame includes a first column and a second column. The support top is coupled to the first column and the second column for rotation about a top axis extending along the length of the support top. A single-handle unlock for the support top is also provided.

Abstract: In certain embodiments, methods of activating the mitochondrial unfolded protein response (UPRmt) and inducing mitohormesis in the brain and/or central nervous system of a mammal are provided where the methods can involve administering to the mammal an effective amount of N-proparglyglycine (N-PPG). In certain embodiments, the mammal is a mammal with a neurodegenerative disease and the method provides for the treatment or prophylaxis of the neurodegenerative disease.

Abstract: Described herein is a computer-implemented method. The method includes: providing digital images and respective formulas for coating compositions with known pigments and/or pigment classes associated with the respective digital images, classifying, using an image annotation tool, for each digital image, each pixel, by visually reviewing the respective digital image pixel-wise, providing, for each digital image, an associated pixel-wise annotated image, training a first neural network with the provided digital images as input and the associated pixel-wise annotated images as output, making the trained first neural network available for applying the trained first neural network to at least one unknown input image of a target coating and for assigning a pigment label and/or a pigment class label to each pixel in the at least one unknown input image, and determining and/or outputting, for each unknown input image, a statistic of corresponding identified pigments and/or pigment classes, respectively.

Abstract: A pre-processing and fulfillment system and method are described. In some implementations, the method may include receiving an order containing a retail component and a pharmacy component, processing the order for the pharmacy component and the retail component, and generating a tracking token identifying the order and authorizing a party to receive a component of the order. The method may include transmitting fulfillment instructions to a fulfillment system based on processed information for the order, and transmitting the tracking token to a computing device of the authorized party. Some implementations may also include receiving a signal indicating receipt of the tracking token and an authorized transfer of the component, and updating a status of the order based on the received signal.

Abstract: Disclosed herein is a method and a device that can measure an unknown target coating; can search, based on the measured data of the target coating, a database for one or more best matching coating formulas, i.e. one or more preliminary matching formulas, within the database; and that can refine the search using an image similarity metric between images of the one or more best matching coating formulas on the one side and images of the target coating on the other side, using deep learning techniques.

Abstract: A pre-processing and fulfillment system and method are described. In some implementations, the method may include receiving an order containing a retail component and a pharmacy component, processing the order for the pharmacy component and the retail component, and generating a tracking token identifying the order and authorizing a party to receive a component of the order. The method may include transmitting fulfillment instructions to a fulfillment system based on processed information for the order, and transmitting the tracking token to a computing device of the authorized party. Some implementations may also include receiving a signal indicating receipt of the tracking token and an authorized transfer of the component, and updating a status of the order based on the received signal.

Abstract: A method for user equipment (UE) based network capability scoring for wireless wide area network management includes receiving parameters associated with a performance of a network, user equipment devices network utilization, and/or user application requirements. The method further includes determining throughput evaluations of data exchanges between UEs and sectors associated with cell sites within the network, and identifying device performance scores based on the throughput evaluations. The device performance scores may be adjusted based on at least one independent metric. The method may evaluate sectors based on the identified device performance scores.

Abstract: Disclosed herein is a computer-implemented method, a respective device, and a non-transitory computer-readable medium. The method includes: obtaining color values, texture values and digital images of a target coating, retrieving from a database one or more preliminary matching formulas based on the color and/or texture values obtained for the target coating, determining sparkle points within the respective obtained images and within the respective images associated with the one or more preliminary matching formulas, creating subimages of each sparkle point from the respective images, providing the created subimages to a convolutional neural network, the convolutional neural network being trained to correlate a respective subimage of a respective sparkle point with a pigment and/or pigment class, and determining, based on an output of the neural network, at least one of the one or more preliminary matching formulas as the formula(s) best matching the target coating.

Abstract: A broadband diagnostics system provides the capability to collect, store and retrieve diagnostic information for the purpose of comparing various channel information to current and existing network elements and conditions. The system allows testing, troubleshooting, tracking, identifying and logging information pertaining to cable, xDSL, FTTx and other networks, and their associated elements. The system also provides identification and testing of network elements deployed at various customer premises, behind a demarcation device.

Abstract: A low-cost, magnetically-driven device that enables visualization and quantification of dynamic changes in cell behavior during mechanical stretch. Using this device, it was observed that nuclei of mouse embryonic skin fibroblasts underwent rapid but divergent responses to strain magnitude, showing nuclear area increase and chromatin decompaction during 5% (low) strain, but nuclear area decrease and chromatin condensation during 20% (high) strain. Only responses to low strain were dependent on calcium, while actin inhibition abrogated any nuclear response and increased stretch-induced DNA damage. Stretch-activation revealed a shift in actin filaments away from (low strain) or towards (high strain) the nuclear periphery. The findings suggest that different pathways control strain level-dependent cell behavior and that mechanical confinement of nuclei through actin may be a protective mechanism during high strain loads.

Abstract: A method for user equipment (UE) based network capability scoring for wireless wide area network management includes receiving parameters associated with a performance of a network, user equipment devices network utilization, and/or user application requirements. The method further includes determining throughput evaluations of data exchanges between UEs and sectors associated with cell sites within the network, and identifying device performance scores based on the throughput evaluations. The device performance scores may be adjusted based on at least one independent metric. The method may evaluate sectors based on the identified device performance scores.

Abstract: Various embodiments are directed to simulating mechanisms of injury utilizing an objective impairment injury score risk model. A computing device may receive injury data from a user. The computing device may perform a security action that protects against unauthorized sharing of the injury data by storing the injury data as a group of linked blocks in a distributed computing system. The computing device may utilize a machine-learning model to generate a set of questions for the user. The questions may be utilized to determine weighting factors associated with the injury data. The computing device may utilize the machine-learning model to determine an impairment injury score based on the weighting factors. The computing device may display an injury risk management report to the user. The computing device may display, based at least in part on the report, a simulation describing a mechanism of the injury described in the injury data.

Abstract: Various embodiments are directed to utilizing an objective impairment injury score risk model. A computing device may receive injury data from a user. The computing device may then perform a security action that protects against unauthorized sharing of the injury data by storing the injury data as a group of linked blocks in a distributed computing system. The computing device may then utilize a machine-learning model to generate a set of questions for the user. The questions may be utilized to determine weighting factors associated with the injury data. The computing device may then utilize the machine-learning model to determine an impairment injury score based on the weighting factors. The may include an objectively determined value associated with a degree of impairment resulting from an injury described in the injury data. Finally, the computing device may display an injury risk management report, based on the score, to the user.

Abstract: A pre-processing and fulfillment system and method are described. In some implementations, the method may include receiving an order containing a retail component and a pharmacy component, processing the order for the pharmacy component and the retail component, and generating a tracking token identifying the order and authorizing a party to receive a component of the order. The method may include transmitting fulfillment instructions to a fulfillment system based on processed information for the order, and transmitting the tracking token to a computing device of the authorized party. Some implementations may also include receiving a signal indicating receipt of the tracking token and an authorized transfer of the component, and updating a status of the order based on the received signal.

Abstract: A broadband diagnostics system provides the capability to collect, store and retrieve diagnostic information for the purpose of comparing various channel information to current and existing network elements and conditions. The system allows testing, troubleshooting, tracking, identifying and logging information pertaining to cable, xDSL, FTTx and other networks, and their associated elements. The system also provides identification and testing of network elements deployed at various customer premises, behind a demarcation device.