Patents by Inventor K. Sree Kumar

K. Sree Kumar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TOCOPHEROL DERIVATIVES AND METHODS OF USE
    Publication number: 20220332692
    Abstract: Tocol derivative compounds, compositions comprising these tocol derivatives and methods of using the tocol derivatives are provided herein. Specifically the tocol derivatives have a partially unsaturated hydrocarbon tail and are thus distinct from the tocopherols. The hydrocarbon tails do not have a trans carbon-carbon double bond in the second isoprene unit of the hydrocarbon tail and are distinct from the tocotrienols. The compounds are expected to allow improved interaction with the a-tocopherol transfer protein receptor than the tocotrienols and better bioactivity than the tocopherols.
    Type: Application
    Filed: July 5, 2022
    Publication date: October 20, 2022
    Applicants: BIOVENTURES, LLC, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Cesar Compadre, Philip J. Breen, Martin Hauer-Jensen, Kottayil Varughese, K. Sree Kumar
  • TOCOPHEROL DERIVATIVES AND METHODS OF USE
    Publication number: 20180244641
    Abstract: Tocol derivative compounds, compositions comprising these tocol derivatives and methods of using the tocol derivatives are provided herein. Specifically the tocol derivatives have a partially unsaturated hydrocarbon tail and are thus distinct from the tocopherols. The hydrocarbon tails do not have a trans carbon-carbon double bond in the second isoprene unit of the hydrocarbon tail and are distinct from the tocotrienols. The compounds are expected to allow improved interaction with the ?-tocopherol transfer protein receptor than the tocotrienols and better bioactivity than the tocopherols.
    Type: Application
    Filed: May 2, 2018
    Publication date: August 30, 2018
    Applicants: BIOVENTURES, LLC, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Cesar Compadre, Phillip J. Breen, Martin Hauer-Jensen, Kottayil Varughese, K. Sree Kumar
  • TOCOPHEROL DERIVATIVES AND METHODS OF USE
    Publication number: 20130158106
    Abstract: Tocol derivative compounds, compositions comprising these tocol derivatives and methods of using the tocol derivatives are provided herein. Specifically the tocol derivatives have a partially unsaturated hydrocarbon tail and are thus distinct from the tocopherols. The hydrocarbon tails do not have a trans carbon-carbon double bond in the second isoprene unit of the hydrocarbon tail and are distinct from the tocotrienols. The compounds are expected to allow improved interaction with the ?-tocopherol transfer protein receptor than the tocotrienols and better bioactivity than the tocopherols.
    Type: Application
    Filed: June 2, 2011
    Publication date: June 20, 2013
    Applicants: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS, THE BOARD OF TRUSTEES FOR THE UNIVERSITY OF ARKANSAS
    Inventors: Philip J. Breen, K. Sree Kumar, Cesar Compadre, Martin Hauer-Jensen, Kottayil Varughese
  • Radiation protection by gamma-tocotrienol
    Patent number: 7919525
    Abstract: The present invention relates to methods for the prevention and treatment of a mammal from radiation-induced internal injury using ?-tocotrienol, ?-tocopherol succinate or ?-tocotrienol succinate. Specifically, the present invention relates to methods for preventing and treating radiation-induced injuries in a mammal by (1) subcutaneous, intramuscular, intraperitoneal, or intravascular injection of a therapeutically effective amount of ?-tocotrienol; or (2) oral administration of a therapeutically effective amount of ?-tocopherol succinate or ?-tocotrienol succinate or both.
    Type: Grant
    Filed: February 17, 2004
    Date of Patent: April 5, 2011
    Assignee: Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
    Inventors: K. Sree Kumar, Venkataraman Srinivasan, Thomas M. Seed, Andreas Papas