Patents by Inventor K. Thomas

K. Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6947474
    Abstract: The architecture of the present invention is premised upon an algorithm involving integration of oblique correlators and RAKE filtering to null interference from other spread spectrum signals. The oblique correlator is based on the non-orthogonal projections that are optimum for nulling structured signals such as spread spectrum signals. In one configuration, space spanned by a first signal associated with a first emitter is orthogonal to an interference space associated with one or more signals of one or more other emitters. RAKE filtering is used to rapidly steer the beam of the multi-antenna system and to mitigate the effects of multipath.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: September 20, 2005
    Assignee: TensorComm, Inc.
    Inventors: Wolfgang Kober, John K. Thomas, Marvin L. Vis
  • Patent number: 6923959
    Abstract: Methods and compositions are described for the treatment of type I insulin-dependent diabetes mellitus and other conditions using newly identified stem cells that are capable of differentiation into a variety of pancreatic islet cells, including insulin-producing beta cells, as well as hepatocytes. Nestin has been identified as a molecular marker for pancreatic stem cells, while cytokeratin-19 serves as a marker for a distinct class of islet ductal cells. Methods are described whereby nestin-positive stem cells can be isolated from pancreatic islets and cultured to obtain further stem cells or pseudo-islet like structures. Methods for ex vivo differentiation of the pancreatic stem cells are disclosed. Methods are described whereby pancreatic stem cells can be isolated, expanded, and transplanted into a patient in need thereof, either allogeneically, isogeneically or xenogenically, to provide replacement for lost or damaged insulin-secreting cells or other cells.
    Type: Grant
    Filed: May 2, 2002
    Date of Patent: August 2, 2005
    Assignee: The General Hospital Corporation
    Inventors: Joel F. Habener, Henryk Zulewski, Elizabeth J. Abraham, Mario Vallejo, Denise L. Faustman, Melissa K. Thomas
  • Patent number: 6903073
    Abstract: The invention features a method of treating deficiency of insulin in a patient, comprising administering to a patient in need thereof hedgehog protein or nucleic acid in an amount effective to raise the level of insulin in the patient.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: June 7, 2005
    Assignee: The General Hospital Corporation
    Inventors: Joel F. Habener, Melissa K. Thomas
  • Patent number: 6886484
    Abstract: A composite tension rod is received in the sleeve portion of a shank that forms part of a terminal fitting, and is spaced from the shank sleeve and connected thereto by a potting resin. The shank sleeve wall tapers out from thin at its distal end to thick at the bury depth of the rod. The rod is tapered outwardly from a point of minimum diameter at its inner end to its full diameter a given distance from the end. The shank sleeve and rod have complementary dual tapering along said length such that as the diameter of the rod along said distance increases, the wall thickness of the shank sleeve decreases. The resin layer and the rod are secured to each other against relative longitudinal movement, as are the resin layer and the shank sleeve. In another aspect of the invention, a tension rod sleeve is fixed to the tension rod and extends over the distal end of the shank sleeve and along all or a majority of the length of the shank sleeve.
    Type: Grant
    Filed: February 12, 2003
    Date of Patent: May 3, 2005
    Inventor: Georg K. Thomas
  • Patent number: 6887492
    Abstract: The present invention is an orally administered pharmaceutical composition that provides for the controlled release of magnesium. The composition has an interactive agent component and a magnesium component which has an enteric coating that controls the release of the magnesium until the composition is in the small intestine or colon. The other component is released in the stomach and is substantially absorbed prior to the release of the magnesium component. Normally, the interactive agent component decreases the absorption of magnesium when the two components are released simultaneously in the gastrointestinal tract.
    Type: Grant
    Filed: December 14, 2001
    Date of Patent: May 3, 2005
    Assignee: Leiner Health Services Corp.
    Inventors: Robert A. Kay, Larry K. Thomas
  • Patent number: 6866843
    Abstract: Methods and compositions are described for the treatment of type I insulin-dependent diabetes mellitus and other conditions using newly identified stem cells that are capable of differentiation into a variety of pancreatic islet cells, including insulin-producing beta cells, as well as hepatocytes. Nestin has been identified as a molecular marker for pancreatic stem cells, while cytokeratin-19 serves as a marker for a distinct class of islet ductal cells. Methods are described whereby nestin-positive stem cells can be isolated from pancreatic islets and cultured to obtain further stem cells or pseudo-islet like structures. Methods for ex vivo differentiation of the pancreatic stem cells are disclosed. Methods are described whereby pancreatic stem cells can be isolated, expanded, and transplanted into a patient in need thereof, either allogeneically, isogeneically or xenogenically, to provide replacement for lost or damaged insulin-secreting cells or other cells.
    Type: Grant
    Filed: December 6, 2000
    Date of Patent: March 15, 2005
    Assignee: Viacell, Inc.
    Inventors: Joel F. Habener, Henryk Zulewski, Elizabeth Abraham, Mario Vallejo, Denise L. Faustman, Melissa K. Thomas
  • Patent number: 6856945
    Abstract: A novel method and apparatus is provided for enabling the computation of a signal in a certain subspace, its projection that lies outside the subspace, and the orthogonal basis for a given matrix. More particularly, the present invention relates to the use of such a method or apparatus for real-time hardware applications since the method and apparatus may be utilized without matrix inversions or square root computations.
    Type: Grant
    Filed: November 19, 2001
    Date of Patent: February 15, 2005
    Assignee: TensorComm, Inc.
    Inventors: John K. Thomas, Anand P. Narayan
  • Patent number: 6848381
    Abstract: A pultruded composite tension rod of hexagonal cross section is provided, as are larger composite rods made up of assemblies of smaller, nested-together parallel hexagonal tension rods that are re-pultruded together. A manufacturing process involving assembling and re-pultruding the smaller rods is also disclosed.
    Type: Grant
    Filed: February 12, 2003
    Date of Patent: February 1, 2005
    Inventor: Georg K. Thomas
  • Publication number: 20040234599
    Abstract: Compositions and methods for maintaining healthy mobile joints and cartilage in humans and animals are disclosed. The composition comprises a glucosamine component dispersed in a controlled-release matrix system capable of releasing the glucosamine over a designated time period. In another aspect, the invention provides compositions and methods for maintaining health mobile joints and cartilage in humans and animals without adversely affecting glucose regulation.
    Type: Application
    Filed: June 9, 2004
    Publication date: November 25, 2004
    Applicant: Leiner Health Services Corp.
    Inventors: Robert A. Kay, Larry K. Thomas, Beuford A. Bogue
  • Patent number: 6816900
    Abstract: An update process is used to update root certificates in a root certificate store of a client computer, maintaining the integrity of the existing root certificates as well as any new root certificates. In one embodiment, the root certificate store is updated by adding root certificates to the store, removing root certificates from the store, or modifying usage restrictions of root certificates in the store. A cryptographically signed message including a certificate trust list, as well as any new root certificates to be added to the root certificate store, is accessed by an update root control to update the root certificates in the root certificate store. The update root control verifies the integrity of the message, and thus the integrity of the certificate trust list contained therein. Once such integrity is verified, the update root control proceeds to update the root certificate store in accordance with the information in the certificate trust list.
    Type: Grant
    Filed: April 4, 2000
    Date of Patent: November 9, 2004
    Assignee: Microsoft Corporation
    Inventors: Keith R. Vogel, Charlie D. Chase, Kelvin S. Yiu, Philip J. Hallin, Louis K. Thomas
  • Publication number: 20040208238
    Abstract: Systems and methods for assisting in location estimation are presented. In one embodiment of the invention, a system improves performance of known location determination algorithms through the use of interference cancellation. In general, the system selectively cancels certain signals to improve Signal to Noise Ratios (SNRs) of certain other signals in a spread spectrum system. These improved SNRs enhance processing, which assists in ascertaining a location of a mobile handset. For example, with improved SNR, the handset may be more able to process signals from more base stations. This processing of additional signals can improve location estimation because certain known location determination algorithms can be used (e.g., TOA and AOA) and location ambiguities and can be resolved.
    Type: Application
    Filed: May 3, 2004
    Publication date: October 21, 2004
    Inventors: John K. Thomas, Anand P. Narayan, Eric S. Olson
  • Patent number: 6788664
    Abstract: A communication system, in particular a fixed wireless access communication system, including a transmission link, such as a broadcast downlink or a multiple access uplink, having a number of channels and apparatus for transmitting circuit switched and packet switched traffic over said transmission link. The system additionally includes a controller device for periodically pre-allocating channels to circuit switched traffic for a set time period dependent on one or more system parameters existing in a previous set time period. The system parameter may be the number of circuit switched connections operating in a previous set time period. The controller device may comprise a monitoring unit for determining a first number equal to the number of operating circuit switched connections in a previous set time period, a summing unit for forming a sum of the first number and an estimated margin and apparatus for allocating the summed number of channels to circuit switched connections for the next set time period.
    Type: Grant
    Filed: November 9, 2000
    Date of Patent: September 7, 2004
    Assignee: Nortel Networks Limited
    Inventors: Mark K Thomas, Peter Beighton, Philip N Johnson
  • Patent number: 6788734
    Abstract: The architecture of the present invention is premised upon an algorithm involving integration of oblique correlators and RAKE filtering to null interference from other spread spectrum signals. The oblique correlator is, of course, based on the non-orthogonal projections that are optimum for nulling structured signals such as spread spectrum signals. RAKE filtering is used to rapidly steer the beam of the multi-antenna system and to mitigate the effects of multipath.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: September 7, 2004
    Inventors: Wolfgang Kober, John K. Thomas, Marvin L. Vis
  • Publication number: 20040160924
    Abstract: The present invention provides systems and methods for parallel interference suppression. In one embodiment of the invention, a processing engine is used to substantially cancel a plurality of interfering signals within a received signal. The processing engine includes a plurality of matrix generators that are used to generate matrices, each matrix comprising elements of a unique interfering signal selected for cancellation. The processing engine also includes one or more processors that use the matrices to generate cancellation operators. A plurality of applicators applies the cancellation operators to parallel but not necessarily unique input signals to substantially cancel the interfering signals from the input signals. These input signals may include received signals, interference cancelled signals and/or PN codes. The embodiments disclosed herein may be particularly advantageous to systems employing CDMA (e.g.
    Type: Application
    Filed: February 6, 2004
    Publication date: August 19, 2004
    Inventors: Anand P. Narayan, John K. Thomas, Eric S. Olson
  • Publication number: 20040154516
    Abstract: A pultruded composite tension rod of hexagonal cross section is provided, as are larger composite rods made up of assemblies of smaller, nested-together parallel hexagonal tension rods that are re-pultruded together. A manufacturing process involving assembling and re-pultruding the smaller rods is also disclosed.
    Type: Application
    Filed: February 12, 2003
    Publication date: August 12, 2004
    Inventor: Georg K. Thomas
  • Publication number: 20040156672
    Abstract: A composite tension rod is received in the sleeve portion of a shank that forms part of a terminal fitting, and is spaced from the shank sleeve and connected thereto by a potting resin. The shank sleeve wall tapers out from thin at its distal end to thick at the bury depth of the rod. The rod is tapered outwardly from a point of minimum diameter at its inner end to its full diameter a given distance from the end. The shank sleeve and rod have complementary dual tapering along said length such that as the diameter of the rod along said distance increases, the wall thickness of the shank sleeve decreases. The resin layer and the rod are secured to each other against relative longitudinal movement, as are the resin layer and the shank sleeve.
    Type: Application
    Filed: February 12, 2003
    Publication date: August 12, 2004
    Inventor: Georg K. Thomas
  • Publication number: 20040151235
    Abstract: The present invention provides systems and methods for decreasing interference in a selected coded signal. The system includes a matrix generator for generating a matrix. The matrix may comprise vectors the elements of which are formed from components of the interference. The interference may exist in the form of co-channel and/or cross channel interference, such as that found in CDMA telephony. The components of this interference may, therefore, be code components of the interference that are used to fill elements of the vectors. Each element of a vector may represent a code component of an interfering coded signal. A processor uses the matrix to substantially remove the interference from the selected coded signal. For example, the processor may generate a projection operator that projects the coded signal substantially orthogonal to the interference such that the impact of interference on the selected coded signal is substantially reduced.
    Type: Application
    Filed: January 23, 2004
    Publication date: August 5, 2004
    Inventors: Eric S. Olson, John K. Thomas, Wolfgang Kober, Robert K. Krumvieda
  • Patent number: 6771214
    Abstract: A method and receiver are disclosed for mitigating or substantially canceling signal interference between signals detected at the receiver. Once a presumed interfering signal(s) is acquired, parameters are determined that allow the interferer(s) to be modeled. An orthogonal projection (for projecting onto a subspace orthogonal to that spanned by the interferer(s)) is applied to the composite of all signals (y) for thereby projecting y onto this subspace, wherein the subspace is non-orthogonal to a representation of desired (but interfered) signal of the composite signals. With the receiver properly equipped to perform this projection operation, interfering signals, multipath, spoofing and/or meaconing can be effectively diminished.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: August 3, 2004
    Assignee: Data Fusion Corporation
    Inventors: Wolfgang Kober, John K. Thomas, Robert K. Krumvieda
  • Patent number: 6767899
    Abstract: Compositions and methods of treatment for conditions in humans and animals which have an inflammatory component, are disclosed. The composition comprises a glucosamine component dispersed in a controlled-release matrix system capable of releasing the glucosamine over a designated time period. In another aspect, the invention provides compositions and methods for the treatment of arthritis in humans and animals without adversely effecting glucose regulation.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: July 27, 2004
    Assignee: Leiner Health Services Corp.
    Inventors: Robert A. Kay, Larry K. Thomas, Beuford A. Bogue
  • Publication number: 20040136445
    Abstract: The present invention is directed to signal cancellation in spread spectrum communication systems. In particular, the present invention provides method and apparatus for selectively canceling interfering signals, even where symbols to be canceled do not align with symbols associated with a desired signal path. Furthermore, the interference cancellation provided by embodiments of the present invention is capable of functioning to remove interference associated with channels utilizing a symbol length that is different than the symbol length of a desired signal path. In accordance with a further embodiment of the present invention, method and apparatus for efficiently calculating projections to enable signal cancellation are provided.
    Type: Application
    Filed: October 15, 2003
    Publication date: July 15, 2004
    Inventors: Eric S. Olson, Anand P. Narayan, Prashant Jain, John K. Thomas