Abstract: A heat and acid resistant probiotics microsphere having a size from 20 to 250 ?m that can readily be incorporated into food or beverages that subsequently undergo thermal treatment. The synbiotic core includes a seed layer formed from at least one polysaccharide. A probiotic microorganism is coated on the seed layer. An acid-resistant shell layer is positioned over the synbiotic core, the acid-resistant shell layer comprising one or more pH-responsive polymers. A heat-resistant bilayer shell is positioned over the acid-resistant shell layer, the heat-resistant bilayer shell including an inner shell layer and an outer shell layer, wherein the inner shell layer includes a heat-resistant liposome layer and the outer layer includes a heat-resistant disaccharide or polysaccharide.

Abstract: The present invention provides a nano-crystallized herbal ingredient-containing package for use in a food processor or being used directly to prepare a herbal decoction. The package includes a housing; single or multiple herbal ingredient nano-crystals; one or more non-additive and anti-caking spacers for preventing caking that blocks solvent flowing through the package towards the single or multiple herbal ingredient nano-crystals during processing by the food processor; and optionally one or more stabilizing agents for stabilizing the single or multiple herbal ingredient nano-crystals during nano-crystallization of the herbal ingredients and during preparation of the herbal decoction. A method of preparing a herbal decoction from the package is also provided.

Abstract: Nano-crystallized herbal ingredient-containing package for use in a food processor or being used directly to prepare an herbal decoction is provided. The nano-crystallized herbal ingredient-containing package comprises a housing; single or multiple herbal ingredient nano-crystals; one or more non-additive and anti-caking spacers for preventing from caking to block solvent flowing through the package towards said single or multiple herbal ingredient nano-crystals during processing by the food processor; and optionally one or more stabilizing agents for stabilizing said single or multiple herbal ingredient nano-crystals during nano-crystallization of the herbal ingredients and during preparation of said herbal decoction. A method of preparing a herbal decoction from the said package is also provided.