Patents by Inventor Kadir Aslan
Kadir Aslan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11967064Abstract: Systems and methods are provided for the rapid sensing of biological and environmental analytes employing a portable digital image capture device, such as a smartphone camera, to capture an image of colorimetric microwave-accelerated bioassays (“MAB”), and a digital image analyzer that processes the colorimetric signals captured by the digital camera to determine the concentration of analyte in a test sample based on a calculated pixel intensity in the captured digital image. Such systems and methods may be used to detect either a disease condition or the presence of a toxin in a particular test specimen and may generate an electronic alert that may serve to alert a medical practitioner of such disease condition or presence of a toxin so that medical intervention may be undertaken. Such electronic alert may optionally be transmitted to the user of a smartphone that captured the image, thus allowing for rapid, in-situ point-of-care analysis and detection of such conditions and immediate medical intervention.Type: GrantFiled: March 17, 2021Date of Patent: April 23, 2024Assignee: Morgan State UniversityInventors: Edward Constance, Kadir Aslan, Enock Bonyi
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Patent number: 11162067Abstract: Compositions including metal nano- and/or micro-particles in solution with photosynthetic bioproduct producing microorganisms. These light harvesting complexes increase growth rates and photosynthetic efficiency of the constituent microorganisms, reducing the light required for a specific production level, or increases production for a specific light level.Type: GrantFiled: August 16, 2017Date of Patent: November 2, 2021Assignee: Morgan State UniversityInventors: Viji Sitther, Kadir Aslan, Behnam Tabatabai
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Publication number: 20210295505Abstract: Systems and methods are provided for the rapid sensing of biological and environmental analytes employing a portable digital image capture device, such as a smartphone camera, to capture an image of colorimetric microwave-accelerated bioassays (“MAB”), and a digital image analyzer that processes the colorimetric signals captured by the digital camera to determine the concentration of analyte in a test sample based on a calculated pixel intensity in the captured digital image. Such systems and methods may be used to detect either a disease condition or the presence of a toxin in a particular test specimen and may generate an electronic alert that may serve to alert a medical practitioner of such disease condition or presence of a toxin so that medical intervention may be undertaken. Such electronic alert may optionally be transmitted to the user of a smartphone that captured the image, thus allowing for rapid, in-situ point-of-care analysis and detection of such conditions and immediate medical intervention.Type: ApplicationFiled: March 17, 2021Publication date: September 23, 2021Inventors: Edward Constance, Kadir Aslan, Enock Bonyi
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Patent number: 10894084Abstract: In this study, we demonstrated a unique application of our Metal-Assisted and Microwave-Accelerated Decrystallization (MAMAD) technique for the de-crystallization of uric acid crystals, which causes gout in humans when monosodium urate crystals accumulate in the synovial fluid found in the joints of bones. Given the shortcomings of the existing treatments for gout, we investigated whether the MAMAD technique can offer an alternative solution to the treatment of gout. Our technique is based on the use of metal nanoparticles (i.e., gold colloids) with low microwave heating to accelerate the de-crystallization process. In this regard, we employed a two-step process; (i) crystallization of uric acid on glass slides, which act as a solid platform to mimic a bone, (ii) de-crystallization of uric acid crystals on glass slides with the addition of gold colloids and low power microwave heating, which act as “nano-bullets” when microwave heated in a solution.Type: GrantFiled: November 21, 2016Date of Patent: January 19, 2021Assignee: Morgan State UniversityInventor: Kadir Aslan
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Publication number: 20180051246Abstract: Compositions including metal nano- and/or micro-particles in solution with photosynthetic bioproduct producing microorganisms. These light harvesting complexes increase growth rates and photosynthetic efficiency of the constituent microorganisms, reducing the light required for a specific production level, or increases production for a specific light level.Type: ApplicationFiled: August 16, 2017Publication date: February 22, 2018Inventors: Viji Sitther, Kadir Aslan
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Publication number: 20170143829Abstract: In this study, we demonstrated a unique application of our Metal-Assisted and Microwave-Accelerated Decrystallization (MAMAD) technique for the de-crystallization of uric acid crystals, which causes gout in humans when monosodium urate crystals accumulate in the synovial fluid found in the joints of bones. Given the shortcomings of the existing treatments for gout, we investigated whether the MAMAD technique can offer an alternative solution to the treatment of gout. Our technique is based on the use of metal nanoparticles (i.e., gold colloids) with low microwave heating to accelerate the de-crystallization process. In this regard, we employed a two-step process; (i) crystallization of uric acid on glass slides, which act as a solid platform to mimic a bone, (ii) de-crystallization of uric acid crystals on glass slides with the addition of gold colloids and low power microwave heating, which act as “nano-bullets” when microwave heated in a solution.Type: ApplicationFiled: November 21, 2016Publication date: May 25, 2017Inventor: Kadir Aslan
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Patent number: 9243017Abstract: The present invention relates to methods for rapid crystallization of amino acids, drug molecules, proteins and DNA/peptides. One method for rapid crystallization of functional group-containing molecules selected from the group consisting of amino acids, drug molecules, proteins and DNA/peptides includes (A) providing at least one metal or metal oxide in particulate or thin film form to provide (a) selective nucleation sites for crystallization of the functional group-containing molecules due to interactions of their functional groups and metal surfaces or engineered metal surfaces and (b) a microwave-transparent medium to create a thermal gradient between the metal surfaces or engineered metal surfaces and a warmer solution containing functional group-containing molecules to be crystallized, and (B) conducting microwave heating to cause the functional group-containing molecules to be crystallized.Type: GrantFiled: October 11, 2012Date of Patent: January 26, 2016Assignee: Morgan State UniversityInventor: Kadir Aslan
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Patent number: 8886464Abstract: The present invention relates to systems and methods using microwave accelerated surface plasmonics for the detection of target species. The system has a metallic surface and the system is exposed to microwave energy for increasing detection time and/or the reaction kinetics of the target species and other interacting participants in the system so that plasmonic emissions from the metallic surface alone or coupled with emissions from a luminescing entity are detected.Type: GrantFiled: April 2, 2007Date of Patent: November 11, 2014Assignee: University of Maryland, Baltimore CountyInventors: Chris D. Geddes, Kadir Aslan
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Patent number: 8182878Abstract: The present invention relates to methods for functionally modifying a polymeric surface for subsequent deposition of metallic particles and/or films, wherein the polymeric surface is modified by increasing hydroxyl and/or amine functional groups thereby providing an activated polymeric surface for deposition of metallic particles to form a fluorescence sensing device. The device can be used for metal-enhanced fluorescence of fluorophores positioned above the metallic particles that can be readily applied to diagnostic or sensing applications of metal-enhanced fluorescence.Type: GrantFiled: November 22, 2011Date of Patent: May 22, 2012Assignee: University of Maryland, Baltimore CountyInventors: Chris D. Geddes, Kadir Aslan
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Publication number: 20120107952Abstract: The present invention relates to systems and methods using microwave accelerated surface plasmonics for the detection of target species, wherein the system has a metallic surface and the system is exposed to microwave energy for increasing detection time and/or the reaction kinetics of the target species and other interacting participants in the system and wherein plasmonic emissions from the metallic surface alone or coupled with emissions from a luminescing entity are detected.Type: ApplicationFiled: April 2, 2007Publication date: May 3, 2012Applicant: UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTEInventors: Chris D. Geddes, Kadir Aslan
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Publication number: 20120063955Abstract: The present invention relates to methods for functionally modifying a polymeric surface for subsequent deposition of metallic particles and/or films, wherein the polymeric surface is modified by increasing hydroxyl and/or amine functional groups thereby providing an activated polymeric surface for deposition of metallic particles to form a fluorescence sensing device. The device can be used for metal-enhanced fluorescence of fluorophores positioned above the metallic particles that can be readily applied to diagnostic or sensing applications of metal-enhanced fluorescence.Type: ApplicationFiled: November 22, 2011Publication date: March 15, 2012Inventors: CHRIS D. GEDDES, KADIR ASLAN
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Patent number: 8075956Abstract: The present invention relates to methods for functionally modifying a polymeric surface for subsequent deposition of metallic particles and/or films, wherein the polymeric surface is modified by increasing hydroxyl and/or amine functional groups thereby providing an activated polymeric surface for deposition of metallic particles to form a fluorescence sensing device. The device can be used for metal-enhanced fluorescence of fluorophores positioned above the metallic particles that can be readily applied to diagnostic or sensing applications of metal-enhanced fluorescence.Type: GrantFiled: October 28, 2005Date of Patent: December 13, 2011Assignee: University of Maryland, Baltimore CountyInventors: Chris D. Geddes, Kadir Aslan
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Publication number: 20090004461Abstract: The present invention relates to methods for functionally modifying a polymeric surface for subsequent deposition of metallic particles and/or films, wherein the polymeric surface is modified by increasing hydroxyl and/or amine functional groups thereby providing an activated polymeric surface for deposition of metallic particles to form a fluorescence sensing device. The device can be used for metal-enhanced fluorescence of fluorophores positioned above the metallic particles that can be readily applied to diagnostic or sensing applications of metal-enhanced fluorescence.Type: ApplicationFiled: October 28, 2005Publication date: January 1, 2009Applicant: UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTEInventors: Chris D. Geddes, Kadir Aslan