Patents by Inventor Kagan Kerman

Kagan Kerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120073987
    Abstract: An electrochemical method of identifying the presence of a target protein in a sample is provided. The method comprises providing a redox probe modified to include a detector that is suitable to bind to the target protein, and exposing the sample to the detector-modified redox probe. A change in the electrochemical signal produced by the redox probe as compared to a control signal is indicative of the presence of the target protein.
    Type: Application
    Filed: June 8, 2010
    Publication date: March 29, 2012
    Inventors: Heinz-Bernhard Kraatz, Kagan Kerman
  • Publication number: 20110218114
    Abstract: A nucleotide triphosphate (NTP) participates in a phosphorylation reaction, wherein a phosphate group is transferred from the NTP to a substrate by a kinase. Provision in a kinase reaction of a NTP whose gamma phosphate is conjugated to an electroactive label results in the transfer of the gamma phosphate-electroactive label conjugate from the NTP to the substrate. The electroactive label is an organic moiety such as a quinone or a nitroheterocycle, or is a metallocene such as a ferrocene or a cobaltocene. Upon transfer of the gamma phosphate-electroactive label conjugate to an electrode-bound substrate by a kinase, the phosphorylation event is detected electrochemically by cyclic voltammetry. Phosphorylation can also be detected by mass spectrometry of a substrate carrying the electroactive label-conjugated gamma phosphate.
    Type: Application
    Filed: September 26, 2008
    Publication date: September 8, 2011
    Inventors: Heinz-Bernhard Kraatz, Kagan Kerman, Haifeng Song
  • Publication number: 20090159458
    Abstract: [Problems] A highly sensitive and accurate determination of a test substance is achieved without the need of complicated procedures. [Means for solving the Problems] The presence or absence or the concentration of a test substance 3 can be determined by gathering around the surface of a working electrode 1 metal microparticles 5 in an amount corresponding to the amount of the test substance 3 contained in a test solution, oxidizing the metal microparticles 5 electrochemically, measuring the value of a current produced by electrochemically reducing the oxidized metal, and determining the presence or absence or the concentration of the substance 3 based on the current value. It is preferred that the electrochemical oxidation of the metal microparticles 5 be conducted while maintaining the potential of the working electrode 1 at a value equal to a potential employed for the electrochemical oxidization of the metal microparticles 5.
    Type: Application
    Filed: March 29, 2007
    Publication date: June 25, 2009
    Applicants: Bio Device Technology Ltd., Japan Advanced Institute of Science and Technology
    Inventors: Eiichi Tamiya, Naoki Nagatani, Teruko Yuhi, Kagan Kerman, Koutarou Idegami, Miyuki Chikae