Patents by Inventor Kah Tiong Kuan

Kah Tiong Kuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MITOMYCIN C PRODRUG LIPOSOME FORMULATIONS AND USES THEREOF
    Publication number: 20200079785
    Abstract: The present invention provides MMC prodrug compounds and liposomal MMC prodrugs and compositions thereof for the treatment of cancer. The compositions include liposomes containing a phosphatidylcholine lipid, a sterol, a PEG-lipid and a MMC prodrug. The present invention also provides liposomal compositions for the treatment of cancer comprising administering to a patient in need thereof a liposome, wherein the liposome comprises: a phosphatidylcholine lipid; a sterol; a PEG-lipid and a MMC prodrug or a pharmaceutically-acceptable salt thereof.
    Type: Application
    Filed: November 8, 2017
    Publication date: March 12, 2020
    Applicant: Mallinckrodt LLC
    Inventors: William McGHEE, Michelle SCHMIDT, Margaret GRAPPERHAUS, Kah Tiong KUAN
  • Remote Assembly of Targeted Nanoparticles Using H-Phosphonate -ENE/-YNE Hydrophosphonylation Reactions
    Publication number: 20160060280
    Abstract: The present invention provides phosphonate compounds and methods of preparing the phosphonate compounds so as to allow, for example, increased capability to modify nanoparticles for targeted drug delivery applications.
    Type: Application
    Filed: November 12, 2015
    Publication date: March 3, 2016
    Inventors: Thomas E. Rogers, Kah Tiong Kuan
  • Remote assembly of targeted nanoparticles using H-phosphate ENE/-YNE hydrophosphonylation reactions
    Patent number: 9216225
    Abstract: The present invention provides phosphonate compounds and methods of preparing the phosphonate compounds so as to allow, for example, increased capability to modify nanoparticles for targeted drug delivery applications.
    Type: Grant
    Filed: August 30, 2012
    Date of Patent: December 22, 2015
    Assignee: MALLINCKRODT LLC
    Inventors: Thomas E. Rogers, Kah Tiong Kuan
  • Remote Assembly of Targeted Nanoparticles using H-Phosphate ENE/-YNE Hydrophosphonylation Reactions
    Publication number: 20130066098
    Abstract: The present invention provides phosphonate compounds and methods of preparing the phosphonate compounds so as to allow, for example, increased capability to modify nanoparticles for targeted drug delivery applications.
    Type: Application
    Filed: August 30, 2012
    Publication date: March 14, 2013
    Applicant: Mallinckrodt LLC
    Inventors: Thomas E. Rogers, Kah Tiong Kuan