Patents by Inventor Kahoko Umeda

Kahoko Umeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small chemical compound which promotes induction of differentiation of stem cells into insulin-producing cells and method for inducing differentiation of stem cells into insulin-producing cells using said small chemical compound
    Patent number: 9617517
    Abstract: A purpose of the present invention is to provide a small chemical compound which especially promotes induction of the differentiation of ES cells into insulin-producing cells. Another purpose of the present invention is to provide: a method for inducing the differentiation of ES cells into insulin-producing cells using the compound; and an agent for promoting induction of the differentiation into insulin-producing cells. Another purpose of the present invention is to provide the thus-induced insulin-producing cells. Provided are: an agent for promoting induction of the differentiation of stem cells derived from a mammal into insulin-producing cells, which contains a compound that is selected from the group consisting of dopamine metabolism inhibitors, serotonin metabolism inhibitors, acetylchotine, acetylcholine degrading enzyme inhibitors and acetylcholine receptor activators; and a method for inducing differentiation using the agent for promoting induction of differentiation.
    Type: Grant
    Filed: May 1, 2012
    Date of Patent: April 11, 2017
    Assignees: NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY, KYOTO UNIVERSITY
    Inventors: Shoen Kume, Daisuke Sakano, Nobuaki Shiraki, Kahoko Umeda, Taiji Yamazoe, Kazuhiko Kume, Motonari Uesugi
  • SMALL CHEMICAL COMPOUND WHICH PROMOTES INDUCTION OF DIFFERENTIATION OF STEM CELLS INTO INSULIN-PRODUCING CELLS AND METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO INSULIN-PRODUCING CELLS USING SAID SMALL CHEMICAL COMPOUND
    Publication number: 20140256043
    Abstract: A purpose of the present invention is to provide a small chemical compound which especially promotes induction of the differentiation of ES cells into insulin-producing cells. Another purpose of the present invention is to provide: a method for inducing the differentiation of ES cells into insulin-producing cells using the compound; and an agent for promoting induction of the differentiation into insulin-producing cells. Another purpose of the present invention is to provide the thus-induced insulin-producing cells. Provided are: an agent for promoting induction of the differentiation of stem cells derived from a mammal into insulin-producing cells, which contains a compound that is selected from the group consisting of dopamine metabolism inhibitors, serotonin metabolism inhibitors, acetylchotine, acetylcholine degrading enzyme inhibitors and acetylcholine receptor activators; and a method for inducing differentiation using the agent for promoting induction of differentiation.
    Type: Application
    Filed: May 1, 2012
    Publication date: September 11, 2014
    Applicants: Kyoto University, National University Corporation Kumamoto University
    Inventors: Shoen Kume, Daisuke Sakano, Nobuaki Shiraki, Kahoko Umeda, Taiji Yamazoe, Kazuhiko Kume, Motonari Uesugi
  • Method for induction of differentiation of ES cell
    Patent number: 8309353
    Abstract: It is an object of the present invention to establish a system for reliably differentiating an ES cell into a hepatic cell. The present invention provides a method for inducing the differentiation of an ES cell into a hepatic cell, which comprises, in the presence of an M15 cell, culturing a mammal-derived ES cell in the presence of activin and bFGF, and then culturing the ES cell in the presence of dexamethasone, HGF, and oncostatin M.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: November 13, 2012
    Assignee: Kumamoto University
    Inventors: Shoen Kume, Nobuaki Shiraki, Kahoko Umeda, Kazuhiko Kume
  • METHOD FOR INDUCTION OF DIFFERENTIATION OF ES CELL
    Publication number: 20120058491
    Abstract: It is an object of the present invention to establish a system for reliably differentiating an ES cell into a hepatic cell. The present invention provides a method for inducing the differentiation of an ES cell into a hepatic cell, which comprises, in the presence of an M15 cell, culturing a mammal-derived ES cell in the presence of activin and bFGF, and then culturing the ES cell in the presence of dexamethasone, HGF, and oncostatin M.
    Type: Application
    Filed: May 30, 2008
    Publication date: March 8, 2012
    Applicant: KUMAMOTO UNIVERSITY
    Inventors: Shoen Kume, Nobuaki Shiraki, Kahoko Umeda, Kazuhiko Kume
  • Polypeptide having cellobiohydrolase activity
    Patent number: 6566113
    Abstract: Polypeptides having the amino acid sequence represented by SEQ ID NO:1 or derived therefrom by at least one of deletion, addition, insertion or substitution of one or more amino acids in the above sequence and showing a cellobiohydrolase activity.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: May 20, 2003
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Masanori Takayama, Kahoko Umeda, Nobuto Koyama, Kiyozo Asada, Ikunoshin Kato