Patents by Inventor Kai Fan Cheng

Kai Fan Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220372022
    Abstract: Synthesis of O-benzotriazole and O-imidazole synthons are described. Uses of synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the synthons and uses of azapeptides and other peptidomimetics are also described.
    Type: Application
    Filed: July 8, 2022
    Publication date: November 24, 2022
    Inventors: Yousef Al-Abed, Kai Fan Cheng
  • Patent number: 11414405
    Abstract: Synthesis of O-benzotriazole and O-imidazole synthons are described. Uses of synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the synthons and uses of azapeptides and other peptidomimetics are also described.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: August 16, 2022
    Assignee: THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
    Inventors: Yousef Al-Abed, Kai Fan Cheng
  • Publication number: 20210130331
    Abstract: Synthesis of O-benzotriazole and O-imidazole synthons are described. Uses of synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the synthons and uses of azapeptides and other peptidomimetics are also described.
    Type: Application
    Filed: January 7, 2021
    Publication date: May 6, 2021
    Applicant: THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
    Inventors: Yousef Al-Abed, Kai Fan Cheng
  • Patent number: 10919882
    Abstract: Synthesis of O-benzotriazole and O-imidazole synthons are described. Uses of synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the synthons and uses of azapeptides and other peptidomimetics are also described.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: February 16, 2021
    Assignee: THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
    Inventors: Yousef Al-Abed, Kai Fan Cheng
  • Publication number: 20200354344
    Abstract: Synthesis of O-benzotriazole and O-imidazole synthons are described. Uses of synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the synthons and uses of azapeptides and other peptidomimetics are also described.
    Type: Application
    Filed: May 8, 2020
    Publication date: November 12, 2020
    Applicant: THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
    Inventors: Yousef Al-Abed, Kai Fan Cheng
  • Patent number: 9457013
    Abstract: Methods are provided for treating pathologies associated with hypoxia with an MIF inhibitor. Methods are also provided for treating a subject having, or at risk for pulmonary hypertension, with an MIF inhibitor. Methods are also provided for reating a subject having, or at risk from, a CNS disorder associated with hypoxia, with an MIF inhibitor. Methods are also provided of treating severe chronic lung disease, hypoxia-induced right ventricular hypertrophy or hypoxia-induced pulmonary vascular remodeling with an MIF inhibitor. Methods of diagnosing a subject with pulmonary hypertension are also provided.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: October 4, 2016
    Assignee: The Feinstein Institute for Medical Research
    Inventors: Edmund Miller, Yousef Al-Abed, Yinzhong Zhang, Kai Fan Cheng
  • Publication number: 20140242091
    Abstract: Methods are provided for treating pathologies associated with hypoxia with an MIF inhibitor. Methods are also provided for treating a subject having, or at risk for pulmonary hypertension, with an MIF inhibitor. Methods are also provided for reating a subject having, or at risk from, a CNS disorder associated with hypoxia, with an MIF inhibitor. Methods are also provided of treating severe chronic lung disease, hypoxia-induced right ventricular hypertrophy or hypoxia-induced pulmonary vascular remodeling with an MIF inhibitor. Methods of diagnosing a subject with pulmonary hypertension are also provided.
    Type: Application
    Filed: May 13, 2014
    Publication date: August 28, 2014
    Applicant: The Feinstein Institute For Medical Research
    Inventors: Edmund Miller, Yousef Al-Abed, Yinzhong Zhang, Kai Fan Cheng
  • Patent number: 8741299
    Abstract: Methods are provided for treating pathologies associated with hypoxia with an MIF inhibitor. Methods are also provided for treating a subject having, or at risk for pulmonary hypertension, with an MIF inhibitor. Methods are also provided for treating a subject having, or at risk from, a CNS disorder associated with hypoxia, with an MIF inhibitor. Methods are also provided of treating severe chronic lung disease, hypoxia-induced right ventricular hypertrophy or hypoxia-induced pulmonary vascular remodeling with an MIF inhibitor. Methods of diagnosing a subject with pulmonary hypertension are also provided.
    Type: Grant
    Filed: June 20, 2012
    Date of Patent: June 3, 2014
    Assignee: The Feinstein Institute for Medical Research
    Inventors: Edmund Miller, Yousef Al-Abed, Yinzhong Zhang, Kai Fan Cheng
  • Publication number: 20130004506
    Abstract: Methods are provided for treating pathologies associated with hypoxia with an MIF inhibitor. Methods are also provided for treating a subject having, or at risk for pulmonary hypertension, with an MIF inhibitor. Methods are also provided for treating a subject having, or at risk from, a CNS disorder associated with hypoxia, with an MIF inhibitor. Methods are also provided of treating severe chronic lung disease, hypoxia-induced right ventricular hypertrophy or hypoxia-induced pulmonary vascular remodeling with an MIF inhibitor. Methods of diagnosing a subject with pulmonary hypertension are also provided.
    Type: Application
    Filed: June 20, 2012
    Publication date: January 3, 2013
    Inventors: Edmund Miller, Yousef Al-Abed, Yinzhong Zhang, Kai Fan Cheng