Patents by Inventor Kai-Hang Su

Kai-Hang Su has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REAL-TIME, SINGLE-STEP BIOASSAY USING NANOPLASMONIC RESONATOR WITH ULTRA-HIGH SENSITIVITY
    Publication number: 20150276610
    Abstract: A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes.
    Type: Application
    Filed: February 7, 2014
    Publication date: October 1, 2015
    Applicant: The Regents of the University of California
    Inventors: Xiang ZHANG, Jonathan A. ELLMAN, Fanqing Frank CHEN, Kai-Hang SU, Qi-Huo WEI, Cheng SUN
  • Real-time, single-step bioassay using nanoplasmonic resonator with ultra-high sensitivity
    Patent number: 8685743
    Abstract: A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: April 1, 2014
    Assignee: The Regents of the University of California
    Inventors: Xiang Zhang, Jonathan A. Ellman, Fanqing Frank Chen, Kai-Hang Su, Qi-Huo Wei, Cheng Sun
  • Time resolved single-step protease activity quantification using nanoplasmonic resonator (NPR) sensor
    Publication number: 20110058164
    Abstract: A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes.
    Type: Application
    Filed: April 30, 2010
    Publication date: March 10, 2011
    Applicant: The Regents of the University of California
    Inventors: Xiang Zhang, Jonathan A. Ellman, Fanqing Frank Chen, Cheng Sun, Kai-Hang Su, Qi-Huo Wei