Patents by Inventor Kai Ling
Kai Ling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250092356Abstract: The present invention relates to a cell differentiation medium composition, a high secretion insulin-producing cells and a preparation method thereof. The high secretion insulin-producing cells obtained by using the cell differentiation medium composition to induce stem cell differentiated under specific conditions can secrete a large amount of insulin in a short time, and when the high-secreting insulin-producing cells are transplanted into the human body, they are not easy to be swallowed by macrophages, which can improve the survival rate of the insulin-producing cells and prolong the time of insulin secretion thereby.Type: ApplicationFiled: December 1, 2024Publication date: March 20, 2025Inventors: Ruei-Yue Liang, Kai-Ling Zhang, Ming-Hsi Chuang, Po-Cheng Lin, Chun-Hung Chen, Pei-Syuan Chao
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Patent number: 12249292Abstract: A display device and a projector are provided. The display device includes a pixel light-emitting panel and multiple color conversion panels. The pixel light-emitting panel includes an N1 number of light-emitting pixel units distributed in an array, and the light-emitting pixel units are driven to emit light through a driver. A first color conversion panel includes an N2 number of first color pixels and an N3 number of first transparent pixels. The first color pixels and the first transparent pixels are disposed relative to the light-emitting pixel units. A second color conversion panel includes an N4 number of second color pixels and an N5 number of second transparent pixels. The second color pixels and the second transparent pixels are disposed relative to the light-emitting pixel units. The lights generated by at least part of the light-emitting pixel units sequentially pass through the first color pixels and the second transparent pixels to achieve the color conversion.Type: GrantFiled: December 15, 2022Date of Patent: March 11, 2025Assignee: Industrial Technology Research InstituteInventors: Hui-Tang Shen, Wei-Hung Kuo, Kai-Ling Liang, Chun-I Wu, Yu-Hsiang Chang
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Patent number: 12204248Abstract: In semiconductor manufacturing, deionized (DI) water or another process fluid is flowed through a nonmetallic pipe and onto a semiconductor wafer. Static electric charge is discharged from the DI water or other process fluid flowing through the nonmetallic pipe via an electrically conductive material disposed on an outside of the nonmetallic pipe. The electrically conductive material disposed on the outside of the nonmetallic pipe is electrically grounded. The nonmetallic pipe may comprise fluoropolymer (PFA) based tubing. In some embodiments, the nonmetallic pipe includes: a PFA-NE pipe connected with a chamber or housing containing the wafer, and a second pipe connected with the PFA-NE pipe by a pipe connector, in which the second pipe is more electrically insulating than the PFA-NE pipe.Type: GrantFiled: August 24, 2021Date of Patent: January 21, 2025Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD.Inventors: Yu-Ling Tseng, Kai-Lun Tseng, Yuan-Yen Lo, Pei-Kao Li, Cheng Yu Wu
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Patent number: 12195754Abstract: The present invention relates to a cell differentiation medium composition, a high secretion insulin-producing cells and a preparation method thereof. The high secretion insulin-producing cells obtained by using the cell differentiation medium composition to induce stem cell differentiated under specific conditions can secrete a large amount of insulin in a short time, and when the high-secreting insulin-producing cells are transplanted into the human body, they are not easy to be swallowed by macrophages, which can improve the survival rate of the insulin-producing cells and prolong the time of insulin secretion thereby.Type: GrantFiled: April 20, 2021Date of Patent: January 14, 2025Assignee: Gwo Xi Stem Cell Applied Technology Co., Ltd.Inventors: Ruei-Yue Liang, Kai-Ling Zhang, Ming-Hsi Chuang, Po-Cheng Lin, Chun-Hung Chen, Pei-Syuan Chao
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Patent number: 12114460Abstract: The present disclosure provides an outdoor electronic device including a shell, electronic assemblies, a rod body and a blower fan. The electronic assemblies are arranged in the shell. The rod body is of a hollow structure and includes a first end and a second end which are reversely arranged; and the first end is connected to the shell. At least one part of the blower fan is arranged on the rod body and includes an air inlet port and an air outlet port. The air inlet port extends to a position close to the electronic assemblies in the shell. The air outlet port is positioned in the rod body and is closer to the second end than the air inlet port.Type: GrantFiled: August 7, 2023Date of Patent: October 8, 2024Assignee: PEGATRON CORPORATIONInventors: Kai-Ling Lin, Chin-Chien Chang, Chia-Chieh Hu
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Publication number: 20240240144Abstract: This disclosure relates to methods and systems for generating T cell precursors from hematopoietic stem and progenitor cells (HSPCs) in vitro. This disclosure discloses that—besides activation of the Notch signaling pathway—activation of tumor necrosis factor receptor 2 (TNFR2) present on the HSPCs is crucial to maximize the generation of T cell precursors. Hence, this disclosure relates to methods and systems, such as artificial thymic organoid systems, wherein agonists for TNFR2, such as transmembrane tumor necrosis factor (tmTNF), are used to maximally generate T cell precursors. The latter T cell precursors are useful for immune reconstitution due to transplantation or immunodeficiency disorders and may be used to generate off-the-shelf chimeric antigen receptor T cells or T cell receptor engineered T cells for immunotherapeutic purposes.Type: ApplicationFiled: May 20, 2022Publication date: July 18, 2024Inventors: Kai Ling Liang, Tom Taghon
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Publication number: 20240206108Abstract: The present disclosure provides an outdoor electronic device including a shell, electronic assemblies, a rod body and a blower fan. The electronic assemblies are arranged in the shell. The rod body is of a hollow structure and includes a first end and a second end which are reversely arranged; and the first end is connected to the shell. At least one part of the blower fan is arranged on the rod body and includes an air inlet port and an air outlet port. The air inlet port extends to a position close to the electronic assemblies in the shell. The air outlet port is positioned in the rod body and is closer to the second end than the air inlet port.Type: ApplicationFiled: August 7, 2023Publication date: June 20, 2024Inventors: Kai-Ling LIN, Chin-Chien CHANG, Chia-Chieh HU
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Publication number: 20240145641Abstract: A color conversion panel and a display device are provided. The color conversion panel includes an opaque substrate and a sapphire substrate. The opaque substrate includes a plurality of first pixel openings, a plurality of second pixel openings and a plurality of third pixel openings. The first pixel openings are filled with red quantum dot material, and the second pixel openings are filled with green quantum dot material. The sapphire substrate is on the opaque substrate. A first surface of the sapphire substrate that faces the opaque substrate has a plurality of first arc surfaces corresponding to the first pixel openings, a plurality of second arc surfaces corresponding to the second pixel openings, and a plurality of third arc surfaces corresponding to the third pixel openings.Type: ApplicationFiled: December 15, 2022Publication date: May 2, 2024Applicant: Industrial Technology Research InstituteInventors: Kai-Ling Liang, Wei-Hung Kuo, Hui-Tang Shen, Chun-I Wu, Suh-Fang Lin
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Patent number: 11970825Abstract: The present invention discloses a structurally stable garden bridge comprising at least one pedestal structure, the pedestal structure comprising at least one elevated pedestal and at least one grounding base; at least one scaffold structure, the scaffold structure comprising at least one elevated side frame and at least one grounding side frame; wherein one end of the elevated pedestal is connected to one grounding base, the other end of the elevated pedestal is connected to another grounding base, forming the pedestal structure; wherein the elevated side frame is connected to one grounding side frame at one end and to another grounding side frame at the other end of the elevated side frame, forming the scaffold structure, the scaffold structure being fixedly attachable to the pedestal structure.Type: GrantFiled: October 12, 2023Date of Patent: April 30, 2024Assignee: BEST CART, INCInventor: Kai Ling
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Publication number: 20240124844Abstract: The present disclosure provides a method for preparing a composition including mesenchymal stem cells, extracellular vesicles produced by the mesenchymal stem cells, and growth factors, the composition prepared by the method, and use of the composition for treating arthritis. The composition of the present disclosure achieves the effect of treating arthritis through various efficacy experiments.Type: ApplicationFiled: October 4, 2023Publication date: April 18, 2024Inventors: Chia-Hsin Lee, Po-Cheng Lin, Yong-Cheng Kao, Ming-Hsi Chuang, Chun-Hung Chen, Chao-Liang Chang, Kai-Ling Zhang
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Publication number: 20240127767Abstract: A display device and a projector are provided. The display device includes a pixel light-emitting panel and multiple color conversion panels. The pixel light-emitting panel includes an N1 number of light-emitting pixel units distributed in an array, and the light-emitting pixel units are driven to emit light through a driver. A first color conversion panel includes an N2 number of first color pixels and an N3 number of first transparent pixels. The first color pixels and the first transparent pixels are disposed relative to the light-emitting pixel units. A second color conversion panel includes an N4 number of second color pixels and an N5 number of second transparent pixels. The second color pixels and the second transparent pixels are disposed relative to the light-emitting pixel units. The lights generated by at least part of the light-emitting pixel units sequentially pass through the first color pixels and the second transparent pixels to achieve the color conversion.Type: ApplicationFiled: December 15, 2022Publication date: April 18, 2024Applicant: Industrial Technology Research InstituteInventors: Hui-Tang Shen, Wei-Hung Kuo, Kai-Ling Liang, Chun-I Wu, Yu-Hsiang Chang
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Publication number: 20240115616Abstract: The present disclosure provides a method for treating liver cirrhosis by using a composition including mesenchymal stem cells, extracellular vesicles produced by the mesenchymal stem cells, and growth factors. The composition of the present disclosure achieves the effect of treating liver cirrhosis through various efficacy experiments.Type: ApplicationFiled: October 4, 2023Publication date: April 11, 2024Inventors: Po-Cheng Lin, Pi-Chun Huang, Zih-Han Hong, Ming-Hsi Chuang, Yi-Chun Lin, Chia-Hsin Lee, Chun-Hung Chen, Chao-Liang Chang, Kai-Ling Zhang
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Publication number: 20240117314Abstract: The present invention relates to a method for preparing a modified stem cell, including the following steps: a cell culture step: culturing stem cells in a first culture medium of a culture dish at a predetermined cell density, and removing the first culture medium after a first culture time to obtain a first cell intermediate; an activity stimulation step: preserving the first cell intermediate in a freezing container having a cell cryopreservation solution, and performing a constant temperature stimulation treatment or a variable temperature stimulation treatment for at least more than 1 day; and a product collection step: after completing the activity stimulation step, placing the freezing container in an environment at a thawing temperature for thawing, and then removing the cell cryopreservation solution to obtain the modified stem cell. The modified stem cell can release at least one or more of IL-4, IL-5, IL-13, G-CSF, Fractalkine, and EGF.Type: ApplicationFiled: October 3, 2023Publication date: April 11, 2024Inventors: Ruei-Yue Liang, Chia-Hsin Lee, Kai-Ling Zhang, Po-Cheng Lin, Ming-Hsi Chuang, Yu-Chen Tsai, Peggy Leh Jiunn Wong
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Publication number: 20240119283Abstract: A method of performing automatic tuning on a deep learning model includes: utilizing an instruction-based learned cost model to estimate a first type of operational performance metrics based on a tuned configuration of layer fusion and tensor tiling; utilizing statistical data gathered during a compilation process of the deep learning model to determine a second type of operational performance metrics based on the tuned configuration of layer fusion and tensor tiling; performing an auto-tuning process to obtain a plurality of optimal configurations based on the first type of operational performance metrics and the second type of operational performance metrics; and configure the deep learning model according to one of the plurality of optimal configurations.Type: ApplicationFiled: October 6, 2023Publication date: April 11, 2024Applicant: MEDIATEK INC.Inventors: Jui-Yang Hsu, Cheng-Sheng Chan, Jen-Chieh Tsai, Huai-Ting Li, Bo-Yu Kuo, Yen-Hao Chen, Kai-Ling Huang, Ping-Yuan Tseng, Tao Tu, Sheng-Je Hung
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Publication number: 20240075071Abstract: Disclosed in the present invention is an optimized cell transplant. The optimized cell transplant is formed by performing gene induction and modification on a mesenchymal stem cell in the form of a small molecule and protein composition. The expression levels of CD200 gene, Galectin-9 gene and VISTA gene can be increased synchronously after cell culture. Vector virus infection and plasmid transfection are not required in the cell preparation process, so that high biological safety and great clinical application value of cells are achieved.Type: ApplicationFiled: November 23, 2022Publication date: March 7, 2024Inventors: Ruei-Yue Liang, Kai-Ling Zhang, Ming-Hsi Chuang, Po-Cheng Lin, Peggy Leh Jiunn Wong, Chia-Hsin Lee
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Publication number: 20230233613Abstract: The present invention provides a pharmaceutical composition for treating chronic stroke, involving injection via brain into the cranium of a patient having chronic stroke for six months or more; the pharmaceutical composition is a suspension at least comprising TS stem cells, an active synergistic component and a growth factor, wherein the expression level of CD34 and CD45 of the TS stem cells is 10% or less, and the expression level of CD90 and CD105 is 90% or more; the active synergistic component is an extracellular vesicle; the growth factor is at least one selected from the group consisting of HGF, G-CSF, Fractalkine, IP-10, EGF, IL-1?, IL-1?, IL-4, IL-5, IL-13, IFN?, TGF? and sCD40L. The present invention overcomes the limitations of previous cell therapy and provides a cell-based preparation that is clinically safe and therapeutically effective for chronic cerebral stroke.Type: ApplicationFiled: October 11, 2022Publication date: July 27, 2023Inventors: Po-Cheng Lin, Pi-Chun Huang, Chia-Hsin Lee, Ming-Hsi Chuang, Chun-Hung Chen, Chao-Liang Chang, Kai-Ling Zhang, Yi-Chun Lin, Yu-Chen Tsai, Peggy Leh Jiunn Wong, Ruei-Yue Liang
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Publication number: 20230201266Abstract: The present disclosure provides a method for treating arthritis by using a stem cell preparation. The stem cell preparation of the present disclosure can effectively delay cartilage degeneration caused by arthritis, and it is confirmed by whole blood analysis and blood biochemical analysis that the stem cell preparation in the form of three-dimensional stem cell spheres provides a safe treatment for arthritis. The present disclosure also provides a method for preparing the stem cell preparation.Type: ApplicationFiled: September 9, 2021Publication date: June 29, 2023Inventors: Feng-Huei Lin, Che-Yung Kuan, Yu-Ying Lin, Ching-Yun Chen, Zhi-Yu Chen, I-Hsuan Yang, Ming-Hsi Chuang, Po-Cheng Lin, Chia-Hsin Lee, Kai-Ling Zhang, Pei-Syuan Chao, Wan-Sin Syu, Chun-Hung Chen, Ting-Ju Wang
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Patent number: 11591027Abstract: A body structure for a vehicle includes an A-pillar and a side sill, wherein the A-pillar includes a vertical front pillar; a front roof pillar extending from an upper end of the vertical front pillar toward an upper rear side thereof; a first reinforcing plate provided in the vertical front pillar and extending in the same direction with the vertical front pillar; and a second reinforcing plate provided in the front roof pillar extending in the same direction with the front roof pillar. The side sill is connected to a lower end of the vertical front pillar and extending along a horizontal direction. The first reinforcing plate is formed to cover a front door hinge mounting portion in the A-pillar and a connection portion of the vertical front pillar and the side sill. An uncoupled portion is formed between the second reinforcing plate and the first reinforcing plate.Type: GrantFiled: November 1, 2021Date of Patent: February 28, 2023Assignee: HONDA MOTOR CO., LTD.Inventors: Kiyohiko Matsuoka, Jianli Yu, Kai Ling
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Publication number: 20230013188Abstract: Structures and related techniques for singulating GaN-on-Si wafers are disclosed. In one aspect, a semiconductor wafer includes a silicon layer, and a gallium nitride (GaN) layer disposed on the silicon layer and defining a plurality of trenches that each extend to the silicon layer. In another aspect, the GaN layer includes one or more gallium nitride layers of different compositions. In yet another aspect, the wafer includes a plurality of dielectric layers disposed on the GaN layer. In yet another aspect, each of the plurality of trenches has a depth that is equal to a sum of a thickness of the GaN layer and a thickness of the plurality of the dielectric layers.Type: ApplicationFiled: July 13, 2022Publication date: January 19, 2023Applicant: Navitas Semiconductor LimitedInventors: George Chu, Nick Fichtenbaum, Kai-Ling Chiu, Daniel M. Kinzer, Maher Hamdan, Pil Sung Park
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Publication number: 20220135140Abstract: A body structure for a vehicle includes an A-pillar and a side sill, wherein the A-pillar includes a vertical front pillar; a front roof pillar extending from an upper end of the vertical front pillar toward an upper rear side thereof; a first reinforcing plate provided in the vertical front pillar and extending in the same direction with the vertical front pillar; and a second reinforcing plate provided in the front roof pillar extending in the same direction with the front roof pillar. The side sill is connected to a lower end of the vertical front pillar and extending along a horizontal direction. The first reinforcing plate is formed to cover a front door hinge mounting portion in the A-pillar and a connection portion of the vertical front pillar and the side sill. An uncoupled portion is formed between the second reinforcing plate and the first reinforcing plate.Type: ApplicationFiled: November 1, 2021Publication date: May 5, 2022Inventors: Kiyohiko Matsuoka, Jianli Yu, Kai Ling