Patents by Inventor Kai Long
Kai Long has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250051362Abstract: A substituted fused heterocyclic compound, and a preparation method therefor and the use thereof. Provided is a compound having the structure of formula (I) or a pharmaceutically acceptable salt thereof. The compound or the pharmaceutically acceptable salt thereof can be used as an ATR inhibitor, which has a high activity.Type: ApplicationFiled: December 19, 2022Publication date: February 13, 2025Inventor: Kai Long
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Patent number: 12221575Abstract: A method for preparing a ZnSe quantum dot, a ZnSe quantum dot, a ZnSe structure and a display device are provided. The method includes preparing a first zinc precursor solution, a second zinc precursor solution, a first selenium precursor solution, and a second selenium precursor solution with a lower reaction activity than the first selenium precursor solution, adding the first selenium precursor solution to the second zinc precursor solution to form an intermediate of the ZnSe quantum dot, performing the following operation at least once to form the ZnSe quantum dot: sequentially adding the first zinc precursor solution and the second selenium precursor solution to the intermediate of the ZnSe quantum dot and making the first zinc precursor solution, the second selenium precursor solution, and the intermediate of the ZnSe quantum dot react.Type: GrantFiled: December 25, 2020Date of Patent: February 11, 2025Assignee: BOE TECHNOLOGY GROUP CO., LTD.Inventors: Haizheng Zhong, Zhiwei Long, Gaoling Yang, Kai Gu, Yang Liu, Zhuo Chen
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Publication number: 20230082273Abstract: Provided is a bispecific recombinant protein, comprising a high affinity tumor-targeting arm and a low affinity fusion protein blocking the interaction of CD47 with SIRP?. The antibody corresponding to the high affinity tumor-targeting arm does not bind to CD47, and its binding affinity to the target antigen on the tumor cell is at least 6 times as great as the binding affinity of monomer fusion protein homodimer, corresponding to the low affinity fusion protein blocking the interaction of CD47 with SIRP?, to a CD47 on the tumor cell, wherein the low affinity fusion protein blocking the interaction of CD47 with SIRP? comprises a SIRP? extracellular truncation. Also provided are nucleic acid molecules encoding recombinant proteins and the use of the recombinant proteins and nucleic acid molecules in the manufacture of a medicament for treating tumors.Type: ApplicationFiled: October 27, 2022Publication date: March 16, 2023Inventors: Liping SONG, Xiaotian CUI, Jian WANG, Haixiang WU, Jiana JIA, Yi FAN, Ganliang ZHANG, Tao LI, Hong XU, Yisha SHE, Kai LONG
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Patent number: 11518810Abstract: Provided is a bispecific recombinant protein, comprising a high affinity tumor-targeting arm and a low affinity fusion protein blocking the interaction of CD47 with SIRP?. The antibody corresponding to the high affinity tumor-targeting arm does not bind to CD47, and its binding affinity to the target antigen on the tumor cell is at least 6 times as great as the binding affinity of monomer fusion protein homodimer corresponding to the low affinity fusion protein blocking the interaction of CD47 with SIRP?, to a CD47 on the tumor cell, wherein the low affinity fusion protein blocking the interaction of CD47 with SIRP? comprises a SIRP? extracellular truncation. Also provided are nucleic acid molecules encoding recombinant proteins and the use of the recombinant proteins and nucleic acid molecules in the manufacture of a medicament for treating tumors.Type: GrantFiled: May 8, 2018Date of Patent: December 6, 2022Assignee: SHANGHAI JMT-BIO TECHNOLOGY CO., LTD.Inventors: Liping Song, Xiaotian Cui, Jian Wang, Haixiang Wu, Jiana Jia, Yi Fan, Ganliang Zhang, Tao Li, Hong Xu, Yisha She, Kai Long
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Patent number: 11354223Abstract: A test script is divided into tests having a sequential order within the test script. An analysis tree of the tests can be generated. Each unique path through the analysis tree includes a subset of the tests as sequentially ordered within the test script. A maximally parallel subset of the unique paths that covers all the tests and according to which the tests are successfully executable is identified. Each test appears in only one unique path of the maximally parallel subset.Type: GrantFiled: March 4, 2020Date of Patent: June 7, 2022Assignee: MICRO FOCUS LLCInventors: Jun-Chen Peng, Xiang Gao, Kai Long, Ruixiang Chen, Lingli Wu
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Patent number: 11345047Abstract: An automated grasping apparatus for precise and clean assembly of a large-aperture optical element includes a reconfigurable end effector, a manipulating robot arm, a computer control unit, a task management software and process database system, a code scanning recognizer, and an electrical auxiliary support system. During an assembling operation, a code of the optical element is scanned by the code scanning recognizer, wherein a suitable process for the optical element is retrieved automatically. The configuration of the end effector is adjusted according to an instruction flow that precision grasping and stable suction of the optical element are achieved by manipulating the end effector. The robot arm is moved to place the optical element at a designated station, and the robot arm carries the end effector to return to an original position after the assembly operation is completed.Type: GrantFiled: December 7, 2017Date of Patent: May 31, 2022Inventors: Hui Wang, Kai Long, Zheng Zhang, Bing Zhao, Tianye Liu, Mengjiya Tian
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Publication number: 20210362352Abstract: An automated grasping apparatus for precise and clean assembly of a large-aperture optical element includes a reconfigurable end effector, a manipulating robot arm, a computer control unit, a task management software and process database system, a code scanning recognizer, and an electrical auxiliary support system. During an assembling operation, a code of the optical element is scanned by the code scanning recognizer, wherein a suitable process for the optical element is retrieved automatically. The configuration of the end effector is adjusted according to an instruction flow that precision grasping and stable suction of the optical element are achieved by manipulating the end effector. The robot arm is moved to place the optical element at a designated station, and the robot arm carries the end effector to return to an original position after the assembly operation is completed.Type: ApplicationFiled: December 7, 2017Publication date: November 25, 2021Inventors: Hui WANG, Kai LONG, Zheng ZHANG, Bing ZHAO, Tianye LIU, Mengjiya TIAN
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Publication number: 20210279166Abstract: A test script is divided into tests having a sequential order within the test script. An analysis tree of the tests can be generated. Each unique path through the analysis tree includes a subset of the tests as sequentially ordered within the test script. A maximally parallel subset of the unique paths that covers all the tests and according to which the tests are successfully executable is identified. Each test appears in only one unique path of the maximally parallel subset.Type: ApplicationFiled: March 4, 2020Publication date: September 9, 2021Inventors: Jun-Chen Peng, Xiang Gao, Kai Long, Ruixiang Chen, Lingli Wu
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Publication number: 20200237030Abstract: The present invention provides a bra cup structure, which includes: two cup sections, each of which comprises: a cup body, which has an outside surface and an inside surface, the cup body including a C-shaped padding section, the C-shaped padding section having a thickness that is gradually increased from an edge of the C-shaped padding section toward a central portion so that the inside surface shows a raised C-shaped area; an outer covering layer, which is set on and covers the outside surface of the cup body; and an inner lining layer, which is set on and covers the inside surface of the cup body, the inner lining layer having a skin contact surface. The C-shaped padding section helps push inwardly the breasts for concentrating toward the middle and pushing up the breasts.Type: ApplicationFiled: October 21, 2019Publication date: July 30, 2020Inventor: KAI-LONG CHENG
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Publication number: 20200157223Abstract: Provided is a bispecific recombinant protein, comprising a high affinity tumor-targeting arm and a low affinity fusion protein blocking the interaction of CD47 with SIRP?. The antibody corresponding to the high affinity tumor-targeting arm does not bind to CD47, and its binding affinity to the target antigen on the tumor cell is at least 6 times as great as the binding affinity of monomer fusion protein homodimer corresponding to the low affinity fusion protein blocking the interaction of CD47 with SIRP?, to a CD47 on the tumor cell, wherein the low affinity fusion protein blocking the interaction of CD47 with SIRP? comprises a SIRP? extracellular truncation. Also provided are nucleic acid molecules encoding recombinant proteins and the use of the recombinant proteins and nucleic acid molecules in the manufacture of a medicament for treating tumors.Type: ApplicationFiled: May 8, 2018Publication date: May 21, 2020Applicant: SHANGHAI JMT-BIO TECHNOLOGY CO., LTDInventors: Liping SONG, Xiaotian CUI, Jian WANG, Haixiang WU, Jiana JIA, Yi FAN, Ganliang ZHANG, Tao LI, Hong XU, Yisha SHE, Kai LONG
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Patent number: 9866015Abstract: A discharge circuit applied in a motherboard includes a platform controller hub (PCH), a first electronic switch, a second electronic switch, and first capacitor. A control terminal of the first electronic switch is coupled to a standby pin of the PCH. A second terminal of the first electronic switch is coupled to the standby power. A control terminal of the second electronic switch is coupled to the second terminal of the first electronic switch. A second terminal of the second electronic switch is coupled to a first power source through a resistor coupled with a capacitor in parallel. The standby pin of the PCH outputs a digital low signal, to control the first electronic switch is turned off rapidly, and the second electronic switch is turned on. A voltage of the first power source is discharged through the resistor rapidly.Type: GrantFiled: April 20, 2015Date of Patent: January 9, 2018Assignees: HONG FU JIN PRECISION INDUSTRY (WuHan) CO., LTD., HON HAI PRECISION INDUSTRY CO., LTD.Inventors: Kai-Long Huang, Chun-Sheng Chen
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Patent number: 9815841Abstract: The present invention relates to novel compounds that inhibit LRRK2 kinase activity, processes for their preparation, to compositions containing them and to their use in the treatment of or prevention of diseases characterized by LRRK2 kinase activity, for example Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis (ALS).Type: GrantFiled: January 28, 2015Date of Patent: November 14, 2017Assignee: GlaxoSmithKline Intellectual Property Development LimitedInventors: Xiao Ding, Qian Liu, Kai Long, Yingxia Sang, Luigi Piero Stasi, Zehong Wan, Qiongfeng Xu, Colin Michael Edge
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Patent number: 9740651Abstract: An electronic device includes a motherboard that includes a south bridge, a universal serial bus (USB) 3.0 connector, and a ground module. The south bridge is connected to the USB3.0 connector for transporting USB3.0 signals and USB2.0 signals. The grounded module is connected to the south bridge and the USB3.0 connector. The south bridge is used for controlling the ground module to work. The USB2.0 signals transmit between the south bridge and the USB3.0 connector flow into the ground, while the ground module is working.Type: GrantFiled: July 6, 2015Date of Patent: August 22, 2017Assignees: HONG FU JIN PRECISION INDUSTRY (WuHan) CO., LTD., HON HAI PRECISION INDUSTRY CO., LTD.Inventors: Kai-Long Huang, Chun-Sheng Chen
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Publication number: 20170022204Abstract: The present invention relates to novel compounds that inhibit LRRK2 kinase activity, processes for their preparation, to compositions containing them and to their use in the treatment of or prevention of diseases characterized by LRRK2 kinase activity, for example Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis (ALS).Type: ApplicationFiled: January 28, 2015Publication date: January 26, 2017Inventors: Xiao DING, Qian LIU, Kai LONG, Yingxia SANG, Luigi Piero STASI, Zehong WAN, Qiongfeng XU, Colin Michael EDGE
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Publication number: 20160342551Abstract: An electronic device includes a motherboard that includes a south bridge, a universal serial bus (USB) 3.0 connector, and a ground module. The south bridge is connected to the USB3.0 connector for transporting USB3.0 signals and USB2.0 signals. The grounded module is connected to the south bridge and the USB3.0 connector. The south bridge is used for controlling the ground module to work. The USB2.0 signals transmit between the south bridge and the USB3.0 connector flow into the ground, while the ground module is working.Type: ApplicationFiled: July 6, 2015Publication date: November 24, 2016Inventors: KAI-LONG HUANG, CHUN-SHENG CHEN
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Patent number: 9478919Abstract: A detection device detects the integrity of a connection between respective connectors of two devices. The detection device includes a control chip, an electronic switch, and an alarm member. The control chip is connected to the alarm member through the electronic switch. When the detection device works, the control chip is connected to the detection pin of the first connector. When the first connector is properly connected to the second connector, the detection pin outputs a first signal to the control chip causing the electronic switch to be off. When the first connector is connected with the second connector improperly, the detection pin outputs a second signal and the control chip turns on the electronic switch, sounding an alarm.Type: GrantFiled: May 19, 2015Date of Patent: October 25, 2016Assignees: HONG FU JIN PRECISION INDUSTRY (WuHan) CO., LTD., HON HAI PRECISION INDUSTRY CO., LTD.Inventors: Kai-Long Huang, Chun-Sheng Chen
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Publication number: 20160308310Abstract: A detection device detects the integrity of a connection between respective connectors of two devices. The detection device includes a control chip, an electronic switch, and an alarm member. The control chip is connected to the alarm member through the electronic switch. When the detection device works, the control chip is connected to the detection pin of the first connector. When the first connector is properly connected to the second connector, the detection pin outputs a first signal to the control chip causing the electronic switch to be off. When the first connector is connected with the second connector improperly, the detection pin outputs a second signal and the control chip turns on the electronic switch, sounding an alarm.Type: ApplicationFiled: May 19, 2015Publication date: October 20, 2016Inventors: KAI-LONG HUANG, CHUN-SHENG CHEN
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Publication number: 20160274652Abstract: A detecting circuit for detecting a signal wire includes a first port, a second port, a control chipset, a transistor, and a LED. The first port is connected to the second port via the signal wire. The first port includes a first display mark bit pin which is configured to connect to ground when a signal wire connects the first port and the second port well. The control chipset includes a control pin and a detecting pin connected to the first display mark bit pin. The transistor is coupled to the control pin and a power source. The LED is connected to a power source via the transistor. The control pin actives the transistor and thereby active the LED, in event the detecting pin detects that the first display mark bit pin is not connected to ground.Type: ApplicationFiled: May 26, 2015Publication date: September 22, 2016Inventors: KAI-LONG HUANG, CHUN-SHENG CHEN
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Publication number: 20160211661Abstract: A discharge circuit applied in a motherboard includes a platform controller hub (PCH), a first electronic switch, a second electronic switch, and first capacitor. A control terminal of the first electronic switch is coupled to a standby pin of the PCH. A second terminal of the first electronic switch is coupled to the standby power. A control terminal of the second electronic switch is coupled to the second terminal of the first electronic switch. A second terminal of the second electronic switch is coupled to a first power source through a resistor coupled with a capacitor in parallel. The standby pin of the PCH outputs a digital low signal, to control the first electronic switch is turned off rapidly, and the second electronic switch is turned on. A voltage of the first power source is discharged through the resistor rapidly.Type: ApplicationFiled: April 20, 2015Publication date: July 21, 2016Inventors: KAI-LONG HUANG, CHUN-SHENG CHEN
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Publication number: 20160072917Abstract: A distributed computing system is disclosed. The system includes a host computer and a plurality of mobile computing devices in communication with the host computer via a communication network. The host computer splits a computing task into a multiple independent calculations and assigns the independent calculations to the mobile computing devices. The mobile computing devices execute the independent calculations and transmit results of the independent calculations to the host computer. The host computer obtains an end result of the computing task by combining the results of the plurality of independent calculations. A distributed computing method is also disclosed.Type: ApplicationFiled: October 28, 2014Publication date: March 10, 2016Inventors: KAI-LONG HUANG, CHUN-SHENG CHEN