Abstract: A method for training an image segmentation model includes calling an encoder to perform feature extraction on a sample image and a scale image to obtain a sample image feature and a scale image feature. The method also includes performing a class activation graph calculation to obtain a sample class activation graph and a scale class activation graph. The method also includes calling a decoder to obtain a sample segmentation result of the sample image, and calling the decoder to obtain a scale segmentation result of the scale image. The method also includes calculating a class activation graph loss and calculating a scale loss. The method also includes training the decoder based on the class activation graph loss and the scale loss.

Abstract: An aqueous synthesis methodology for the preparation of silica nanoparticles (SNPs), core-shell SNPs having, for example, a size of 2 to 15 nm and narrow size-dispersion with size control below 1 nm, i.e. at the level of a single atomic layer. Different types of dyes, including near infrared (NIR) emitters, can be covalently encapsulated within and brightness can be enhanced via addition of extra silica shells. The surface may be functionalized with polyethylene glycol (PEG) groups and, optionally, specific surface ligands. This aqueous synthesis methodology also enables synthesis of 2 to 15 nm sized fluorescent core and core-shell aluminosilicate nanoparticles (ASNPs) which may also be surface functionalized. Encapsulation efficiency and brightness of highly negatively charged NIR fluorophores is enhanced relative to the corresponding SNPs without aluminum.

Abstract: Described herein is a multiplex platform that uses ultrasmall nanoparticles (e.g., C dots and C? dots) to graphically differentiate specific nerves (e.g., sensory nerves vs. motor nerves) for nerve transplants and other surgeries. Also described herein is a multiplex platform that uses ultrasmall nanoparticles (e.g., C dots and C? dots) to graphically differentiate between different types of lymph nodes and/or lymphatic pathways, e.g., to safely and effectively perform vascularized lymph node transplantation in the treatment of lymphedema. Also described herein is a multiplex platform that uses ultrasmall nanoparticles (e.g., C dots and C? dots) to graphically differentiate parathyroid tissue.

Abstract: Disclosed in the present invention is a compound as represented by formula (IA) or formula (IC) or a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof. The definition of each group in the formula is shown in the description for details. Further disclosed are a pharmaceutical composition containing the compound and the use thereof in the preparation of a drug for preventing and/or treating diseases or conditions related to HPK1 activity.

Abstract: A method for three-dimensional edge detection includes obtaining, for each of plural two-dimensional slices of a three-dimensional image, a two-dimensional object detection result and a two-dimensional edge detection result, stacking the two-dimensional object detection results into a three-dimensional object detection result, and stacking the two-dimensional edge detection results into a three-dimensional edge detection result. The method also includes performing encoding according to a feature map of the three-dimensional image, the three-dimensional object detection result, and the three-dimensional edge detection result, to obtain an encoding result, and performing decoding according to the encoding result, the three-dimensional object detection result, and the three-dimensional edge detection result, to obtain an optimized three-dimensional edge detection result of the three-dimensional image.

Abstract: Silica nanorings, methods of making silica nanorings, and uses of silica nanorings. The silica nanorings may be PEGylated. The silica nanorings may be surface functionalized, which may be surface selective functionalization, with one or more polyethylene glycol (PEG) group(s), one or more display group(s), one or more functional group(s), or a combination thereof. The silica nanorings may have a size of 5 to 20 nm. The silica nanorings may be made using micelles. The absence or presence of the micelles during PEGylation and/or functionalization allows for surface selective functionalization. The silica nanorings may be used in various diagnostic and/or treatment methods.

Abstract: In an image processing method, style conversion is performed on a sample image by using a generation network, to obtain a reference image. Style recognition is performed on the reference image by using an adversarial network, to determine a style loss between the reference image and the sample image. Image content recognition is performed on the reference image and the sample image, to determine a content loss between the reference image and the sample image. The generation network is trained based on the style loss and the content loss, to obtain a trained generation network.

Abstract: Disclosed are an aroyl substituted tricyclic compound, a preparation method therefor and use thereof. Specifically, the aroyl substituted tricyclic compound of the present invention has a structure of formula (C), and has, as a BTK inhibitor, the advantages of high activity, good selectivity and low toxic and side effects.

Abstract: An image processing method includes obtaining a sample image and a generative adversarial network (GAN), including a generation network and an adversarial network, and performing style conversion on the sample image, to obtain a reference image. The method further includes performing global style recognition on the reference image, to determine a global style loss between the reference image and the sample image, and performing image content recognition on the reference image and the sample image, to determine a content loss between the reference image and the sample image. The method also includes performing local style recognition on the reference image and the sample image, to determine a local style loss of the reference image and a local style loss of the sample image, training the generation network to obtain a trained generation network, and performing style conversion on a to-be-processed image by using the trained generation network.

Abstract: An aqueous synthesis methodology for the preparation of silica nanoparticles (SNPs), core-shell SNPs having, for example, a size of 2 to 15 nm and narrow size-dispersion with size control below 1 nm, i.e. at the level of a single atomic layer. Different types of dyes, including near infrared (NIR) emitters, can be covalently encapsulated within and brightness can be enhanced via addition of extra silica shells. The surface may be functionalized with polyethylene glycol (PEG) groups and, optionally, specific surface ligands. This aqueous synthesis methodology also enables synthesis of 2 to 15 nm sized fluorescent core and core-shell aluminosilicate nanoparticles (ASNPs) which may also be surface functionalized. Encapsulation efficiency and brightness of highly negatively charged NIR fluorophores is enhanced relative to the corresponding SNPs without aluminum.

Abstract: Embodiments of the disclosure disclose a text processing method and apparatus, and an electronic device. A specific embodiment of the method includes: obtaining text to be processed, determining target entity words in the text to be processed, thereby generating a target entity word set; determining a word explanation corresponding to the target entity word in the target entity word set based on the text to be processed, and obtaining related information corresponding to the word explanation; and pushing target information to present the text to be processed, and displaying the target entity word in the target entity word set in a preset display mode in the text to be processed, where the target information includes the target entity word set, the word explanation corresponding to the target entity word in the target entity word set, and the related information.

Abstract: Provided is a pyridino- or pyrimido-cyclic compound having an inhibitory effect on a KRAS gene mutation, or a pharmaceutically acceptable salt, a stereoisomer or a solvate thereof, wherein the structure of the compound is as shown in formula (AI) or (AII), and the definition of each group in the formula is detailed in the description. In addition, also disclosed are a pharmaceutical composition comprising the compound, and the use thereof in the preparation of a cancer drug.

Abstract: A tunneling system includes a bolter miner, a bolter-integrated transportation machine, a transfer machine, a self-moving tail and a belt conveyor. The bolter miner includes a rack, a cutting device, and a bolt support device. The bolt support device includes a lifting assembly, a work platform, a first drilling frame assembly and a stabilizing assembly. The lifting assembly is arranged between the rack and the work platform. The first drilling frame assembly and the stabilizing assembly are arranged on the work platform. The bolter-integrated transportation machine is arranged behind the bolter miner and configured to transfer coal rock cut and conveyed by the bolter miner. One end of the transfer machine is connected with the bolter-integrated transportation machine, and the other end of the transfer machine is lapped with the self-moving tail. The belt conveyor is arranged behind the self-moving tail.

Abstract: A multi-use monitoring system is disclosed, which comprises an electronic device, multiple sensor devices, multiple cameras, at least one wireless interface, and a remote electronic device. According to the present invention, the sensor devices are adopted for detecting multiple environmental parameters such as gas level, humidity and temperature, and the multiple cameras are controlled to acquire images from the poultry bred in a breeding environment. Therefore, after receiving the images and the environmental parameters from the electronic device, the remote electronic device can extract at least one poultry characteristic from the images, and then correlate the environmental parameters to the poultry characteristic(s). As a result, the remote electronic device can subsequently calculate an evaluation score according to the growth and/or health state of the poultry, such that the breeder can plan how to distribute the breeding resources for the poultry.

Abstract: A tunnel tunneling system includes a bolter miner, a bolter-integrated transportation machine, a transfer machine, a self-moving tail and a belt conveyor. The bolter miner includes a rack, a cutting device, a drilling device and a control device. The cutting device is arranged on the rack and is swingable in an up-down direction, and has a lowest swing angle and a highest swing angle. The drilling device is arranged on the rack, and includes a drilling rig and a sensor. The drilling rig is configured to drill a tunnel floor and/or a tunnel roof, and the sensor is configured to monitor a set parameter of the drilling rig and generate a monitoring data signal when the drilling rig is drilling. The control device is configured to receive and analyze the monitoring data signal.

Abstract: Methods of semiconductor processing may include contacting a substrate with a first slurry and a first platen. The substrate may include silicon oxide defining one or more features, a liner extending across the silicon oxide and within the one or more features, and a copper-containing layer deposited on the liner and extending within the one or more features. The first slurry and the first platen may remove a first portion of the copper-containing layer. The methods may include contacting the substrate with a second slurry and a second platen, which may remove at least a portion of the liner. The methods may include contacting the substrate with a third slurry and a third platen, which may remove a second portion of the copper-containing layer. The methods may include contacting the substrate with a fourth slurry and a fourth platen, which may remove at least a portion of the silicon oxide.

Abstract: A CT image generation method and apparatus, a computer device, and a computer-readable storage medium are presented. The method includes obtaining a first X-ray image and a second X-ray image, the first X-ray image and the second X-ray image being X-ray images acquired for a target object from two orthogonal viewing angles; calling a generator to perform three-dimensional reconstruction on the first X-ray image and the second X-ray image, to obtain a three-dimensional model of the target object; and obtaining a CT image of the target object according to the three-dimensional model of the target object.

Abstract: A tunneling and anchoring machine (100) and a tunneling system, the tunneling and anchoring machine (100) comprising a rack (1), a cutting device (2), a drilling device (3) and a control device; the cutting device (2) has a lowest swing angle (B) and a highest swing angle (a); the drilling device (3) comprises a drilling machine (31) and a sensor, the sensor is electrically connected to the drilling machine (31), the drilling machine (31) is suitable for drilling a roadway floor and/or a roadway roof, and the sensor is suitable for, when the drilling machine (31) is drilling, monitoring a set parameter of the drilling machine (31) and generating a monitoring data signal; the sensor is electrically connected to the control device, and the control device is suitable for receiving and analyzing the monitoring data signal; when the drilling machine (31) drills a first thickness of the roadway floor, if the monitoring data signal is greater than a first threshold, the control device is suitable for adjusting the l

Abstract: A bolter miner includes a rack, a cutting device and a bolt support device. The cutting device is configured for a cutting operation and is arranged on the rack to swing up and down. The bolt support device includes a lifting assembly, a work platform, a first drilling frame assembly and a stabilization assembly. The lifting assembly is arranged between the rack and the work platform and is configured to lift the work platform. The first drilling frame assembly and the stabilization assembly are arranged on the work platform. The first drilling frame assembly has a bolt support position and an avoidance position. The work platform can extend and retract to switch the bolt support position and the avoidance position of the first drilling frame assembly. The stabilization assembly can be supported between the cutting device and a tunnel roof, so as to enhance the stability of the first drilling frame assembly during a bolt support operation.

Abstract: A method, computer system, and computer program product are provided for dynamic power saving for wireless access points. It is determined that a wireless client has not requested to connect to a first access point for a first threshold duration of time. Power is disabled to one or more front-end modules of a plurality of front-end modules associated with the first access point except for one designated front-end module that remains powered. Monitoring is performed for an incoming request to connect to the first access point. Power is restored to the one or more front-end modules of the plurality of front-end modules.