Abstract: Devices and methods for preventing knee sprain injuries. To protect the knee joint from knee sprain injuries, the device comprises a sensing part configured to sense data associated with knee motion; an analyzing part configured to analyze the knee motion data to determine a knee articulation; and a stimulating part configured to stimulate one or more lower limb muscles to initiate an earlier muscle reaction than would naturally occur in response to the determined knee joint articulation. The determined knee joint articulation may include knee joint articulation or a particular type of articulation such as a knee sprain movement associated with knee sprain. The methods involve sensing data associated with knee joint motion, analyzing the data to determine a knee joint articulation; and stimulating one or more lower limb muscles to initiate an early muscle reaction within the determined knee joint articulation.

Abstract: An irrigation solution containing about 15-50 mM ascorbic acid and/or a pharmaceutically acceptable salt thereof, and electrolytes, and their uses in a surgery, a surgical manipulation, a medical process or in promoting the healing of a tendon or ligament injury in a subject.

Abstract: Devices and methods for preventing ankle sprain injuries. To protect the ankle joint from acute ankle supination or inversion sprain injuries, the device comprises a sensing part configured to sense data of an ankle motion; an analyzing part configured to analyze the data to judge whether the motion is a sprain motion; and a stimulating part configured to stimulate one or more lower limb muscles against the motion in light of a result of the analyzing. The method also involves sensing data of an ankle motion; analyzing the data to judge whether the motion is a sprain motion; and stimulating one or more lower limb muscles against the motion if the motion is a sprain motion.

Abstract: Devices and methods for preventing ankle sprain injuries. To protect the ankle joint from acute ankle supination or inversion sprain injuries, the device comprises a sensing part configured to sense data of an ankle motion; an analyzing part configured to analyze the data to judge whether the motion is a sprain motion; and a stimulating part configured to stimulate one or more lower limb muscles against the motion in light of a result of the analyzing. The method also involves sensing data of an ankle motion; analyzing the data to judge whether the motion is a sprain motion; and stimulating one or more lower limb muscles against the motion if the motion is a sprain motion.

Abstract: An organic extract of a Chinese herbal medicine Geum Japonicum thunb var. has been identified that displayed potent stimulatory effects on rapid agiogenesis (<24 h), myogenesis and blocking fibrosis in traumatized skeletal muscles. The extract has displayed potent dual effects on angiogenesis and myogenesis in damaged skeletal muscles leading to complete skeletal muscle healing in rabbit and rat animal models. The extract of the present invention can be developed into an effective therapeutic drug for the treatment of skeletal muscle trauma, soft tissue healing including burn, skin wound and operation cut, and bone fracture and defect healings.