Abstract: The invention relates to a method for determining the temporal phase of acute kidney injury, comprising obtaining a test sample from a subject and measuring the expression level of at least one biomarker selected from the group comprising Chac1, Birc5 and Angptl7. The invention also relates to a method for determining the early early phase, the late early phase, the severity and/or timing of acute kidney injury via analysis of the biomarkers Chac1, Birc5 and/or Angptl7, in addition to a test kit for carrying out said methods and antibodies directed against Chac1, Birc5 or Angptl7.

Abstract: The invention relates to a method for determining the temporal phase of acute kidney injury, comprising obtaining a test sample from a subject and measuring the expression level of at least one biomarker selected from the group comprising Chac1, Birc5 and Angpt17. The invention also relates to a method for determining the early early phase, the late early phase, the severity and/or timing of acute kidney injury via analysis of the biomarkers Chac1, Birc5 and/or Angptl7, in addition to a test kit for carrying out said methods and antibodies directed against Chac1, Birc5 or Angptl7.

Abstract: The invention is directed to compositions comprising two or more compounds selected from the group consisting of stem cell factor, cytokine like factor-1, CXCL14, FRAS1, neuropeptide Y, Semaphorin 3C, Cyr 61, USAG-1, IGF-BP2, WNT 6, WNT 9B, SHH, BMP-7, kit ligand, SOSTDC1, semaphorin 4D, NME3, laminin gamma 2, laminin alpha 5, laminin gamma 1, collagen triple helix repeat containing 1, nephronectin, collagen XVIII and laminin alpha 1, and methods of using the compositions to modulate the growth of embryonic or adult kidney tissue or to treat kidney damage in a mammal. The invention is also related to a kit for treating kidney damage.