Patents by Inventor Kai Sohn

Kai Sohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quantitative analysis of short double-stranded cell free DNA in liquid biopsy
    Publication number: 20250122578
    Abstract: Disclosed is a method for identifying a cfDNA derived biomarker for a physiological condition, disease or disorder comprising: a) isolating cfDNA from a sample of a subject known to be in the physiological condition or suffer from the disease or disorder; b) selecting short double-stranded cfDNA fragments; c) determining the nucleic acid sequences of said short double-stranded cfDNA fragments; d) comparing the nucleic acid sequences of said short double-stranded cfDNA fragments to a reference; and; e) based on said comparison in step d) identifying at least one cfDNA derived biomarker associated with the physiological condition, disease or disorder; a method for assessing a physiological condition, disease or disorder; a method for determining efficacy of treating a physiological condition, disease or disorder; use of a cfDNA derived biomarker in a sample for assessing a disease or disorder in a subject; and a device for detecting a cfDNA derived biomarker in a sample.
    Type: Application
    Filed: October 10, 2024
    Publication date: April 17, 2025
    Applicant: Fraunhofer-Gesellschaft zur Forderung der angewandten Forschung e.V.
    Inventors: Christina HARTWIG, Jan MULLER, Kai SOHN, Mirko SONNTAG
  • Method and device for nucleic acid based diagnostic approaches including the determination of a deviant condition, especially a health condition and/or a pathogenic condition of a sample
    Patent number: 10910088
    Abstract: The present invention relates to a method and a device for a nucleic acid based diagnostic approach including the determination of a deviant condition of a sample, wherein the deviant condition is preferably a health condition and/or a pathogenic condition.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: February 2, 2021
    Assignees: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER, UNIVERSITÄT STUTTGART, MEDIZINISCHE UNIVERSITÄT WIEN, UNIVERSITÄT WIEN
    Inventors: Kai Sohn, Silke Grumaz, Philip Stevens, Arndt Von Haeseler
  • METHOD AND DEVICE FOR NUCLEIC ACID BASED DIAGNOSTIC APPROACHES INCLUDING THE DETERMINATION OF A DEVIANT CONDITION, ESPECIALLY A HEALTH CONDITION AND/OR A PATHOGENIC CONDITION OF A SAMPLE
    Publication number: 20180307795
    Abstract: The present invention relates to a method and a device for a nucleic acid based diagnostic approach including the determination of a deviant condition of a sample, wherein the deviant condition is preferably a health condition and/or a pathogenic condition.
    Type: Application
    Filed: September 8, 2016
    Publication date: October 25, 2018
    Inventors: Kai SOHN, Silke GRUMAZ, Philip STEVENS, Arndt VON HAESELER
  • Electrophoretic Separation Method for Analyzing Gene Expression
    Publication number: 20080261209
    Abstract: The following invention relates to an improved method of quantitative or qualitative analysis of gene expression of a biological material.
    Type: Application
    Filed: September 30, 2005
    Publication date: October 23, 2008
    Inventors: Kai Sohn, Steffen Rupp
  • Hyphen-specific factors from
    Patent number: 7220574
    Abstract: The present invention relates to biochips, in particular nucleotide chips, which contain hyphen-specific proteins coding nucleotides, protein chips which contain hyphen-specific proteins, and antibody chips which contain antibodies directed against these hyphen-specific proteins, diagnostic compositions which contain these nucleotide, protein, or antibody chips, processes for the location and identification of substances which are therapeutically effective against diseases caused by types of Candida and processes for the diagnosis of a disease caused by Candida.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: May 22, 2007
    Assignee: Fraunhafer-Gasellschaft zur Forderung der Angewandten Forschung E.V.
    Inventors: Steffen Rupp, Franz-Josef Johannes, Kai Sohn
  • Hypha-specific factors from candida albicans
    Publication number: 20040014061
    Abstract: The present invention relates to biochips, in particular nucleotide chips, which contain hyphen-specific proteins coding nucleotides, protein chips which contain hyphen-specific proteins, and antibody chips which contain antibodies directed against these hyphen-specific proteins, diagnostic compositions which contain these nucleotide, protein, or antibody chips, processes for the location and identification of substances which are therapeutically effective against diseases caused by types of Candida and processes for the diagnosis of a disease caused by Candida.
    Type: Application
    Filed: July 2, 2003
    Publication date: January 22, 2004
    Inventors: Steffen Rupp, Franz-Josef Johannes, Kai Sohn