Patents by Inventor Kai Zwingenberger

Kai Zwingenberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lactam derivatives as immunomodulating agents
    Patent number: 6500845
    Abstract: The invention relates to the use of certain lactam derivatives corresponding to the formula I as pharmaceutical compounds with immunomodulatory activity, to new lactam derivatives, and to processes for preparing these derivatives.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 31, 2002
    Assignee: Gruenenthal GmbH
    Inventors: Horst Boehlke, Michael Finkam, Oswald Zimmer, Johannes Schneider, Stephan Wnendt, Kai Zwingenberger
  • Acylated n-hydroxy methyl thalidomide prodrugs with immunomodulator action
    Patent number: 6417197
    Abstract: Thalidomide prodrugs of the formula I: in which R is —CHR1—NHR2 or —(CH2)nCOOH; R1 is H or C1-4 alkyl; R2 is H, C1-3 alkyl, C(O)—CH2—NHR3 or an amino-protective group, R3 is H or an amino-protective group, and n is an integer from 2 to 4, in the form of their free bases or of salts with physiologically acceptable acids, as well as a process for preparation of such prodrugs and the use of such prodrugs as an active drug substance.
    Type: Grant
    Filed: December 14, 1998
    Date of Patent: July 9, 2002
    Assignee: Gruenenthal GmbH
    Inventors: Johannes Schneider, Werner Winter, Stephan Wnendt, Kai Zwingenberger, Kurt Eger, Michaela Akermann
  • Compounds analogous to thalidomide from the class comprising piperidine-2,6-diones
    Patent number: 6110941
    Abstract: Compounds analogous to thalidomide from the class comprising piperidine-2,6-diones are described, as are a method of preparing them and their use in drugs.
    Type: Grant
    Filed: January 29, 1998
    Date of Patent: August 29, 2000
    Assignee: Gruenenthal GmbH
    Inventors: Oswald Zimmer, Werner Winter, Stephan Wnendt, Kai Zwingenberger, Kurt Eger, Uwe Teubert
  • Substituted 2, 4-imidazolidinedione compounds as pharmaceutical active ingredients
    Patent number: 6004963
    Abstract: A substituted 2,4-imidazolidinedione compound corresponding to the formula I ##STR1## a process for production thereof and the use of these compounds in a pharmaceutical preparation are described. Substituents R1, R2, R3 and R4 have the same meaning as defined in the specification.
    Type: Grant
    Filed: October 25, 1996
    Date of Patent: December 21, 1999
    Assignee: Gruenenthal GmbH
    Inventors: Oswald Zimmer, Hoerst Boehlke, Stephan Wnendt, Cornelia Geist, Kai Zwingenberger