Abstract: A method of operating a computing device in support of improved accessibility includes displaying a user interface to an application on a display screen of the computing device, wherein the computing device includes an accessibility assistant that reads an audible description of an element of the user interface; initiating, on the computing device, a virtual assistant that conducts an audible conversation between a user and the virtual assistant through at least a microphone and a speaker associated with the computing device, wherein the virtual assistant is not integrated with an operating system of the computing device; inhibiting an ability of the accessibility assistant to read the audible description of the element of the user interface; and upon transition of the virtual assistant from an active state, enabling the ability of the accessibility assistant.

Abstract: A method of operating a computing device in support of improved accessibility includes displaying a user interface to an application on a display screen of the computing device, wherein the computing device includes an accessibility assistant that reads an audible description of an element of the user interface; initiating, on the computing device, a virtual assistant that conducts an audible conversation between a user and the virtual assistant through at least a microphone and a speaker associated with the computing device, wherein the virtual assistant is not integrated with an operating system of the computing device; inhibiting an ability of the accessibility assistant to read the audible description of the element of the user interface; and upon transition of the virtual assistant from an active state, enabling the ability of the accessibility assistant.

Abstract: The present invention provides a composition, a kit and the use thereof, as well as the method for detecting the cell proliferative abnormality in individuals or grading the disease degree in the individuals. The composition comprises nucleic acids for detecting the methylation level within at least one target region of a gene and the fragment thereof.

Abstract: A method of operating a computing device in support of improved accessibility includes displaying a user interface to an application on a display screen of the computing device, wherein the computing device includes an accessibility assistant that reads an audible description of an element of the user interface; initiating, on the computing device, a virtual assistant that conducts an audible conversation between a user and the virtual assistant through at least a microphone and a speaker associated with the computing device, wherein the virtual assistant is not integrated with an operating system of the computing device; inhibiting an ability of the accessibility assistant to read the audible description of the element of the user interface; and upon transition of the virtual assistant from an active state, enabling the ability of the accessibility assistant.

Abstract: The present invention provides a glycosylated CEA-specific single-chain antibody, and a chimeric antigen receptor (CAR) targeting a glycosylated CEA, which can be used in manufacture of an agent or a medicament for diagnosis or treatment of a tumor overexpressing glycosylated CEA.

Abstract: The present invention provides a composition, a kit and the use thereof, as well as the method for detecting the cell proliferative abnormality in individuals or grading the disease degree in the individuals. The composition comprises nucleic acids for detecting the methylation level within at least one target region of a gene and the fragment thereof.

Abstract: The present invention provides a glycosylated CEA-specific single-chain antibody, and a chimeric antigen receptor (CAR) targeting a glycosylated CEA, which can be used in manufacture of an agent or a medicament for diagnosis or treatment of a tumor overexpressing glycosylated CEA.