Patents by Inventor Kaija Maher

Kaija Maher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Typing of human enteroviruses
    Patent number: 7435539
    Abstract: The present invention discloses a method for detecting the presence of an enterovirus in a clinical sample. The invention additionally discloses a method for typing an enterovirus in a clinical sample. Both methods employ a set of primer oligonucleotides for reverse transcription and amplification that hybridize to conserved regions of the enterovirus genome, and that provide amplicons that include significant portions of the VP1 region that are characteristic of the various serotypes. In the typing method, the invention further provides a database consisting of nucleotide sequences from prototypical enteroviral serotypes, which is used to type the clinical sample by comparing the sequence of its amplicon with each prototypical sequence in the database. The invention additionally provides mixtures of primer oligonucleotides, and a kit for use in conducting the typing method that includes a mixture of the primer oligonucleotides.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: October 14, 2008
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Steven Oberste, Kaija Maher, David R. Kilpatrick, Mark A. Pallansch
  • Typing of human enteroviruses
    Publication number: 20050123908
    Abstract: The present invention discloses a method for detecting the presence of an enterovirus in a clinical sample. The invention additionally discloses a method for typing an enterovirus in a clinical sample. Both methods employ a set of primer oligonucleotides for reverse transcription and amplification that hybridize to conserved regions of the enterovirus genome, and that provide amplicons that include significant portions of the VP1 region that are characteristic of the various serotypes. In the typing method, the invention further provides a database consisting of nucleotide sequences from prototypical enteroviral serotypes, which is used to type the clinical sample by comparing the sequence of its amplicon with each prototypical sequence in the database.
    Type: Application
    Filed: January 25, 2005
    Publication date: June 9, 2005
    Inventors: Steven Oberste, Kaija Maher, David Kilpatrick, Mark Pallansch
  • Typing of human enteroviruses
    Patent number: 6846621
    Abstract: The present invention discloses a method for detecting the presence of an enterovirus in a clinical sample. The invention additionally discloses a method for typing an enterovirus in a clinical sample. Both methods employ a set of primer oligonucleotides for reverse transcription and amplification that hybridize to conserved regions of the enterovirus genome, and that provide amplicons that include significant portions of the VP1 region that are characteristic of the various serotypes. In the typing method, the invention further provides a database consisting of nucleotide sequences from prototypical enteroviral serotypes, which is used to type the clinical sample by comparing the sequence of its amplicon with each prototypical sequence in the database. The invention additionally provides mixtures of primer oligonucleotides, and a kit for use in conducting the typing method that includes a mixture of the primer oligonucleotides.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: January 25, 2005
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Steven Oberste, Kaija Maher, David R. Kilpatrick, Mark A. Pallansch