Patents by Inventor Kaijing Yan

Kaijing Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230390353
    Abstract: The present invention provides a pharmaceutical composition for treating myocardial ischemia, comprising Salvia Miltiorrhiza medicinal material 250-700 parts by weight, Radix Notoginseng medicinal material 50-150 parts by weight, Borneolum Syntheticum 3-9 parts by weight, and ranolazine 25-100 parts by weight. According to a further aspect of the present invention, there is provided a use of a pharmaceutical composition for preparation of a medicine for prevention and/or treatment of myocardial ischemia.
    Type: Application
    Filed: September 5, 2022
    Publication date: December 7, 2023
    Inventors: He SUN, Kaijing YAN, Xiaohui MA, Shunnan ZHANG, Yi HE, Haoshu XIONG, Yongfeng ZHENG, Xinxin LI, Hongbo ZHANG, Yanmei LI, Jing WANG, Tiantian WEN, Zhipeng HUO, Lijun FAN, Wei SUN, Jianchun WANG, Nan CAI, Rui YANG, Jingjing ZHANG
  • Publication number: 20230201293
    Abstract: The present invention relates to an application of a traditional Chinese medicine composition and formulation thereof in the preparation of medicaments for preventing and/or treating novel coronavirus pneumonia.
    Type: Application
    Filed: April 28, 2021
    Publication date: June 29, 2023
    Inventors: He SUN, Xuefeng SU, Zhiyong ZHONG, Anni LI, Xijun YAN, Naifeng WU, Kaijing YAN
  • Publication number: 20220151984
    Abstract: A pharmaceutical composition is prepared from the following raw materials (in parts by weight): silybin (8.75-60), phospholipid (15-65), a Pu'er tea extract (25-200), and vitamin E (6.25-40). The composition has the effect of treating non-alcoholic fatty liver diseases.
    Type: Application
    Filed: January 28, 2022
    Publication date: May 19, 2022
    Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: He SUN, Xijun YAN, Naifeng WU, Kaijing YAN, Yonghong ZHU, Shunnan ZHANG, Xiaolin BAI, Xiaohui MA, Yi HE, Ting LI, Lei LI
  • Patent number: 11318112
    Abstract: A pharmaceutical composition is prepared from the following raw materials (in parts by weight): silybin (8.75-60), phospholipid (15-65), a Pu'er tea extract (25-200), and vitamin E (6.25-40). The composition has the effect of treating non-alcoholic fatty liver diseases.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: May 3, 2022
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: He Sun, Xijun Yan, Naifeng Wu, Kaijing Yan, Yonghong Zhu, Shunnan Zhang, Xiaolin Bai, Xiaohui Ma, Yi He, Ting Li, Lei Li
  • Patent number: 11013694
    Abstract: The present invention relates to a preparation method for a traditional Chinese medicine drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, the present invention relates to a micro drop pill preparation method with high drug-loading capacity, simple preparation process and high production rate and a micro drop pill prepared by using the method. Specially, The drop pill preparation method used comprises the following steps: (1) material melting step: heat melting a medicine and a drop pill matrix to obtain a molten medicine liquid; (2) dropping step: delivering the molten medicine liquid to a dripper, and acquiring medicine drops of the molten medicine liquid by means of vibration dropping; and, (3) condensation step: cooling the medicine drops with a cooling gas to obtain micro drop pills.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: May 25, 2021
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Xiaobing Sun, Shunnan Zhang, Zhengliang Ye, Hai'ou Dong, Hongbo Zhang, Wensheng Zhang, Lihong Zhou, Chenming Li, Cong Chen, Xiaofeng Liu, Shiqing Wang, Changsheng Rong, Yongfeng Zheng, Lijun Fan
  • Patent number: 10918575
    Abstract: An intelligent dripping pill machine for continuous liquid solidification comprises: a feeding device (1), a material combining device (2), a homogenizing device (3), a dripping device (4) and a de-oiling device (5) sequentially connected via a transmission channel. The intelligent dripping pill machine removes, via high-speed centrifugation, a cooling liquid attached to dripping pills, and each component device is connected compactly, thereby achieving a continuous manufacturing operation, and reducing an occupied space of the devices as a whole while ensuring the yield of the dripping pills.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: February 16, 2021
    Assignee: Tasly Pharmaceutical Group Co., LTD.
    Inventors: Kaijing Yan, Xiaobing Sun, Changsheng Rong, Xuefei Cai, Liang Wang
  • Patent number: 10813840
    Abstract: An intelligent continuous manufacturing method via liquid cooling of dripping pills comprises the following steps: (1) feeding: weighing and transferring multiple materials respectively; (2) material combining: performing staged heating on the materials transferred in step (1), and mixing the same to obtain a material mixture, wherein an RSD of an effective ingredient in the material mixture ?5%; (3) homogenizing: pressurizing the material mixture obtained in step (2), and increasing the temperature, so as to obtain a homogenized material having the RSD of the effective ingredient in the material mixture ?5%; (4) dripping: performing vibration dripping on the homogenized material obtained in step (3) to obtain dripping pills, delivering the dripping pills into a cooling liquid to be cooled and then transferred; and (5) de-oiling: removing the cooling liquid on surfaces of the dripping pills obtained in step (4) via tilting centrifugation.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: October 27, 2020
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Kaijing Yan, Xiaobing Sun, Changsheng Rong, Xuefei Cai, Liang Wang
  • Patent number: 10507197
    Abstract: Disclosed is a pharmaceutical composition containing silibinin, which is prepared from the following bulk drugs by weight ratio: 8.75-60 parts of silibinin, 15-65 parts of phospholipid, and 25-200 parts of Pu'er tea extract. The drug has the function of treating non-alcoholic fatty liver.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: December 17, 2019
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Naifeng Wu, Xijun Yan, He Sun, Kaijing Yan, Yonghong Zhu, Shunnan Zhang, Xiaolin Bai, Yi He, Xiaohui Ma, Ting Li, Lei Li
  • Publication number: 20190274962
    Abstract: The present invention relates to a preparation method for a traditional Chinese medicine drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, the present invention relates to a micro drop pill preparation method with high drug-loading capacity, simple preparation process and high production rate and a micro drop pill prepared by using the method. Specially, The drop pill preparation method used comprises the following steps: (1) material melting step: heat melting a medicine and a drop pill matrix to obtain a molten medicine liquid; (2) dropping step: delivering the molten medicine liquid to a dripper, and acquiring medicine drops of the molten medicine liquid by means of vibration dropping; and, (3) condensation step: cooling the medicine drops with a cooling gas to obtain micro drop pills.
    Type: Application
    Filed: May 24, 2019
    Publication date: September 12, 2019
    Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Xiaobing Sun, Shunnan Zhang, Zhengliang Ye, Hai'ou Dong, Hongbo Zhang, Wensheng Zhang, Lihong Zhou, Chenming Li, Cong Chen, Xiaofeng Liu, Shiqing Wang, Changsheng Rong, Yongfeng Zheng, Lijun Fan
  • Patent number: 10376490
    Abstract: A pharmaceutical composition for treating non-alcoholic fatty liver diseases consists of a silybin-phospholipid complex preparation and Pu'er tea/tea product according to a weight ratio of 0.5-2.5:0.3-10, wherein the silybin-phospholipid complex capsule preparation and the Pu'er teat/tea product are separately packaged.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: August 13, 2019
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Naifeng Wu, Xijun Yan, He Sun, Kaijing Yan, Yonghong Zhu, Shunnan Zhang, Xiaolin Bai, Yi He, Xiaohui Ma, Ting Li
  • Patent number: 10376491
    Abstract: Disclosed are a pharmaceutical composition for treating non-alcoholic fatty liver and a method for preparing same. The composition is prepared from the following hulk drugs by weight ratio: 8.75-60 parts of silibinin, 15-65 parts of phospholipid, 25-200 parts of Pu'er tea extract, and 5-50 parts of radix puerariae extract.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: August 13, 2019
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, He Sun, Kaijing Yan, Yonghong Zhu, Xiaohui Ma, Shunnan Zhang, Changwen Li, Xiaolin Bai, Ting Li, Lei Li, Yi He
  • Patent number: 10307396
    Abstract: A pharmaceutical composition. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 8.75-60 parts of silybin, 15-65 parts of phospholipid, 25-200 parts of a Pu'er tea extract, 6.25-40 parts of vitamin E, and 8.3-60 parts of L-carnitine. The composition can be used for treating non-alcoholic fatty liver diseases.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: June 4, 2019
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: He Sun, Xijun Yan, Naifeng Wu, Kaijing Yan, Yonghong Zhu, Shunnan Zhang, Xiaolin Bai, Xiaohui Ma, Yi He, Ting Li, Lei Li
  • Patent number: 10307395
    Abstract: A pharmaceutical composition for treating non-alcoholic fatty liver diseases. The pharmaceutical composition is prepared from 8.75-60 parts by weight of silybin, 15-65 parts by weight of phospholipid, 25-150 parts by weight of a Pu'er tea extract, and 10.425-60 parts by weight of L-carnitine.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: June 4, 2019
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: He Sun, Xijun Yan, Naifeng Wu, Kaijing Yan, Yonghong Zhu, Shunnan Zhang, Xiaolin Bai, Xiaohui Ma, Yi He, Ting Li, Lei Li
  • Publication number: 20180263851
    Abstract: An intelligent dripping pill machine for continuous liquid solidification comprises: a feeding device (1), a material combining device (2), a homogenizing device (3), a dripping device (4) and a de-oiling device (5) sequentially connected via a transmission channel. The intelligent dripping pill machine removes, via high-speed centrifugation, a cooling liquid attached to dripping pills, and each component device is connected compactly, thereby achieving a continuous manufacturing operation, and reducing an occupied space of the devices as a whole while ensuring the yield of the dripping pills.
    Type: Application
    Filed: September 14, 2016
    Publication date: September 20, 2018
    Inventors: Kaijing YAN, Xiaobing SUN, Changsheng RONG, Xuefei CAI, Liang WANG
  • Publication number: 20180256450
    Abstract: An intelligent continuous manufacturing method via liquid cooling of dripping pills comprises the following steps:(1) feeding: weighing and transferring multiple materials respectively; (2) material combining: performing staged heating on the materials transferred in step (1), and mixing the same to obtain a material mixture, wherein an RSD of an effective ingredient in the material mixture ?5%; (3) homogenizing: pressurizing the material mixture obtained in step (2), and increasing the temperature, so as to obtain a homogenized material having the RSD of the effective ingredient in the material mixture ?5%; (4) dripping: performing vibration dripping on the homogenized material obtained in step (3) to obtain dripping pills, delivering the dripping pills into a cooling liquid to be cooled and then transferred; and (5) de-oiling: removing the cooling liquid on surfaces of the dripping pills obtained in step (4) via tilting centrifugation.
    Type: Application
    Filed: September 14, 2016
    Publication date: September 13, 2018
    Inventors: Kaijing YAN, Xiaobing SUN, Changsheng RONG, Xuefei CAI, Liang WANG
  • Patent number: 9999630
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: June 19, 2018
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong
  • Patent number: 9987320
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: June 5, 2018
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong, Yongfeng Zheng, Lijun Fan
  • Publication number: 20180104215
    Abstract: A pharmaceutical composition for treating non-alcoholic fatty liver diseases. The pharmaceutical composition is prepared from 8.75-60 parts by weight of silybin, 15-65 parts by weight of phospholipid, 25-150 parts by weight of a Pu'er tea extract, and 10.425-60 parts by weight of L-carnitine.
    Type: Application
    Filed: March 22, 2016
    Publication date: April 19, 2018
    Inventors: He SUN, Xijun YAN, Naifeng WU, Kaijing YAN, Yonghong ZHU, Shunnan ZHANG, Xiaolin BAI, Xiaohui MA, Yi HE, Ting LI, Lei LI
  • Patent number: RE49035
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: April 19, 2022
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong
  • Patent number: RE49050
    Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: April 26, 2022
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Kaijing Yan, Zhengliang Ye, Shunnan Zhang, Lihong Zhou, Wensheng Zhang, Hai'ou Dong, Yongfeng Zheng, Lijun Fan