Abstract: A natural absorbent excipient having multifunction developed by a twin-screw hot melt extrusion process is disclosed. The present invention discloses a natural excipient composition comprising: (a) natural coconut husk and/or coir pith powder from the husk of coconut, the fruit of Cocos nucifera; and (b) at least one polyol compound consisting of glycerol, sorbitol, polyethene glycol (PEG), propylene glycol (PG), and combinations thereof, wherein the weight ratio of (a) to (b) is in the range of 1:1-6:4.

Abstract: Pharmaceutical and nutraceutical composition in the form of oral dispersible films (ODFs) using twin-screw hot melt extrusion was described. In the present disclosure, there is provided an oral dispersible film composition comprising: (a) maltodextrin; and (b) hydroxypropyl cellulose, wherein the weight ratio of maltodextrin to hydroxypropyl cellulose is in the range of 1:1-3:1. The prepared films of pharmaceutical and nutraceutical composition are uniform in film thickness, have excellent physical attributes and can be directly packed after cutting.