Patents by Inventor Kailash CHADHA

Kailash CHADHA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kit for immunological detection of TNF-alpha, sTNFR1 and IL-8 in prostate cancer
    Patent number: 10393746
    Abstract: The disclosure provides methods of using biomarkers to improve diagnosis of forms of prostate. The method includes testing a biological sample from an individual for a interleukin-8 (IL-8), Tumor necrosis factor alpha (TNF-?) and soluble tumor necrosis factor-? receptor 1 (sTNFR1), and may further include testing for prostate serum antigen (PSA). Use of these markers in combination provides tests that are more sensitive and specific than PSA in differentiating benign versus malignant prostate disease and/or localized CaP versus metastatic CaP and show that the specificity and sensitivity of a PSA-based CaP diagnosis can be significantly enhanced by measuring IL-8, TNF-? and sTNFR1.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: August 27, 2019
    Assignee: Health Research, Inc.
    Inventors: Kailash Chadha, Willie Underwood, Austin Miller
  • BIOMARKERS FOR PROSTATE CANCER
    Publication number: 20180275130
    Abstract: The disclosure provides methods of using biomarkers to improve diagnosis of forms of prostate. The method includes testing a biological sample from an individual for a interleukin-8 (IL-8), Tumor necrosis factor alpha (TNF-?) and soluble tumor necrosis factor-? receptor 1 (sTNFR1), and may further include testing for prostate serum antigen (PSA). Use of these markers in combination provides tests that are more sensitive and specific than PSA in differentiating benign versus malignant prostate disease and/or localized CaP versus metastatic CaP and show that the specificity and sensitivity of a PSA-based CaP diagnosis can be significantly enhanced by measuring IL-8, TNF-? and sTNFR1.
    Type: Application
    Filed: May 30, 2018
    Publication date: September 27, 2018
    Inventors: Kailash CHADHA, Willie UNDERWOOD, Austin MILLER
  • Biomarkers for prostate cancer comprising interleukin-8 (IL-8), tumor necrosis factor alpha and soluble tumor necrosis factor-alpha receptor 1
    Patent number: 9995748
    Abstract: The disclosure provides methods of using biomarkers to improve diagnosis of forms of prostate. The method includes testing a biological sample from an individual for a interleukin-8 (IL-8), Tumor necrosis factor alpha (TNF-a) and soluble tumor necrosis factor-? receptor 1 (sTNFR1), and may further include testing for prostate serum antigen (PSA). Use of these markers in combination provides tests that are more sensitive and specific than PSA in differentiating benign versus malignant prostate disease and/or localized CaP versus metastatic CaP and show that the specificity and sensitivity of a PSA-based CaP diagnosis can be significantly enhanced by measuring IL-8, TNF-a and sTNFR1.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: June 12, 2018
    Assignee: Health Research, Inc.
    Inventors: Kailash Chadha, Willie Underwood, Austin Miller
  • BIOMARKERS FOR PROSTATE CANCER
    Publication number: 20160202260
    Abstract: The disclosure provides methods of using biomarkers to improve diagnosis of forms of prostate. The method includes testing a biological sample from an individual for a interleukin-8 (IL-8), Tumor necrosis factor alpha (TNF-a) and soluble tumor necrosis factor-? receptor 1 (sTNFR1), and may further include testing for prostate serum antigen (PSA). Use of these markers in combination provides tests that are more sensitive and specific than PSA in differentiating benign versus malignant prostate disease and/or localized CaP versus metastatic CaP and show that the specificity and sensitivity of a PSA-based CaP diagnosis can be significantly enhanced by measuring IL-8, TNF-a and sTNFR1.
    Type: Application
    Filed: August 12, 2014
    Publication date: July 14, 2016
    Inventors: Kailash CHADHA, Willie UNDERWOOD, Austin MILLER