Patents by Inventor Kairat Madin

Kairat Madin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR OBTAINING IMMUNOGLOBULIN ENCODING NUCLEIC ACID
    Publication number: 20170107550
    Abstract: The current invention is directed to a method for obtaining a nucleic acid encoding an immunoglobulin variable domain from a single cell comprising the following steps: performing a first polymerase chain reaction with three to six 5?-primer and one 3?-primer, performing with the product of the first polymerase chain reaction a second polymerase chain reaction with thirteen to sixteen 5?-primer and one 3?-primer, whereby the distance of the binding locations of the primer employed in the second polymerase chain reaction is reduced compared to the first polymerase chain reaction.
    Type: Application
    Filed: June 21, 2016
    Publication date: April 20, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Hans-Willi Krell, Alexander Lifke, Valeria Lifke, Kairat Madin, Christian Weilke
  • Method for obtaining immunoglobulin encoding nucleic acid
    Patent number: 9399670
    Abstract: The current invention is directed to a method for obtaining a nucleic acid encoding an immunoglobulin variable domain from a single cell comprising the following steps: —performing a first polymerase chain reaction with three to six 5?-primer and one 3?-primer, performing with the product of the first polymerase chain reaction a second polymerase chain reaction with thirteen to sixteen 5?-primer and one 3?-primer, whereby the distance of the binding locations of the primer employed in the second polymerase chain reaction is reduced compared to the first polymerase chain reaction.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: July 26, 2016
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Hans-Willi Krell, Alexander Lifke, Valeria Lifke, Kairat Madin, Christian Weilke
  • METHOD FOR OBTAINING FAB FRAGMENTS FROM SINGLE ANTIBODY PRODUCING CELLS BY MULTIPLEXED CPR IN COMBINATION WITH TaqMan PROBES
    Publication number: 20150024434
    Abstract: Herein is reported a method for a multiplex one tube real-time reverse-transcriptase gene-specific polymerase chain reaction for the amplification and quantification of cognate IgG heavy and light chains encoding nucleic acids (human IgG isotype) from a single cell.
    Type: Application
    Filed: September 20, 2012
    Publication date: January 22, 2015
    Inventors: Hans-Willi Krell, Alexander Lifke, Valeria Lifke, Kairat Madin, Christian Weilke
  • METHOD FOR OBTAINING IMMUNOGLOBULIN ENCODING NUCLEIC ACID
    Publication number: 20110306094
    Abstract: The current invention is directed to a method for obtaining a nucleic acid encoding an immunoglobulin variable domain from a single cell comprising the following steps:—performing a first polymerase chain reaction with three to six 5?-primer and one 3?-primer, performing with the product of the first polymerase chain reaction a second polymerase chain reaction with thirteen to sixteen 5?-primer and one 3?-primer, whereby the distance of the binding locations of the primer employed in the second polymerase chain reaction is reduced compared to the first polymerase chain reaction.
    Type: Application
    Filed: February 18, 2010
    Publication date: December 15, 2011
    Inventors: Hans-Willi Krell, Alexander Lifke, Valeria Lifke, Kairat Madin, Christian Weilke