Patents by Inventor Kaixi ZHANG

Kaixi ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Beta-peptido sugar-copolymer
    Patent number: 11970576
    Abstract: There is provided a ?-peptido sugar-copolymer having the structure of formula (I) as defined herein, or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, or a salt thereof, or a mixture of the same. There is provided a process to make the ?-peptido sugar-copolymer as defined herein. There are further provided medical applications of the ?-peptido sugar-copolymer as defined herein. In a preferred embodiment, a block-like copolymer poly(amido-D-glucose)-block-poly-?-(L)-homolysine (PDGu-b-PBLK) synthesized via anionic ring-opening polymerization (ROP) demonstrates an antimicrobial efficacy, an enhanced selectivity towards different bacteria, biocompatibility vs. mammalian cells and spontaneous assembly.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: April 30, 2024
    Assignee: NANYANG TECHNOLOGICAL UNIVERSITY
    Inventors: Bee Eng Mary Chan, Yu Du, Rubi Zamudio Vazquez, Kaixi Zhang, Zhangyong Si, Yuguang Mu, Hongwei Duan
  • BETA-PEPTIDO SUGAR-COPOLYMER
    Publication number: 20220332892
    Abstract: There is provided a ?-peptido sugar-copolymer having the structure of formula (I) as defined herein, or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, or a salt thereof, or a mixture of the same. There is provided a process to make the ?-peptido sugar-copolymer as defined herein. There are further provided medical applications of the ?-peptido sugar-copolymer as defined herein. In a preferred embodiment, a block-like copolymer poly(amido-D-glucose)-block-poly-?-(L)-homolysine (PDGu-b-PBLK) synthesized via anionic ring-opening polymerization (ROP) demonstrates an antimicrobial efficacy, an enhanced selectivity towards different bacteria, biocompatibility vs. mammalian cells and spontaneous assembly.
    Type: Application
    Filed: January 12, 2018
    Publication date: October 20, 2022
    Inventors: Bee Eng Mary CHAN, Yu DU, Rubi ZAMUDIO VAZQUEZ, Kaixi ZHANG, Zhangyong SI, Yuguang MU, Hongwei DUAN