Patents by Inventor Kaiyuan Yang
Kaiyuan Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7803319Abstract: A diagnostic test kit for detecting an analyte residing in a test sample is provided. The kit employs a lateral flow device that contains a membrane. A metering channel is formed in the membrane that is capable of delivering a controlled volume of the test sample to a detection zone upon initiation of the assay. Such a metering channel is particularly effective for embodiments in which the test sample has a relatively low volume, such as less than about 100 microliters, in some embodiments less than about 25 microliters, and in some embodiments, less than about 10 microliters. For example, whole blood drops obtained from patients with a lancet from low-pain areas (due to reduced nerve endings than finger), such as the forearm, thigh, or other alternate sites, may have a volume of from about 0.1 to about 5 microliters. Despite their low volume, the present inventors have discovered that the blood drops may still be accurately analyzed for the presence of an analyte using lateral flow detection techniques.Type: GrantFiled: April 29, 2005Date of Patent: September 28, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Kaiyuan Yang, Ning Wei, Shawn Ray Feaster
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Patent number: 7790471Abstract: A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. A sample membrane is utilized having a collection region and a detection region, the collection region having a known saturation volume for the intended test sample. A barrier is defined between the collection region and the detection region. The collection region is saturated with the test sample having a volume of less than about 100 microliters so that a known volume of the test sample is contained in the collection region. The barrier is removed from between the collection region and detection region of the membrane and a diluent is supplied to the collection region of the membrane to facilitate flow of the test sample from the collection region to the detection region of the membrane.Type: GrantFiled: October 5, 2007Date of Patent: September 7, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: James M. Takeuchi, Xuedong Song, Kaiyuan Yang, Ning Wei, Shawn R. Feaster
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Patent number: 7754197Abstract: A method for reducing odor is provided. The method comprises forming a coordination complex between a transition metal and a polydentate compound, and contacting the coordinated complex with an odorous compound. The transition metal provides one or more active sites for capturing the odorous compound. In some embodiments, the polydentate compound may be a polyalkylimine, such as polyethyleneimine, polypropyleneimine, or a dendrimer thereof.Type: GrantFiled: October 16, 2003Date of Patent: July 13, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Bin Wu, Kevin P. McGrath, Jaeho Kim, Bao Trong Kim, Sharon Linda Greene, Yanbin Huang, Kaiyuan Yang
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Publication number: 20100159599Abstract: Various modifications to a porous substrate, such as employed in lateral flow assay devices, to regulate or modify the flow rate and/or flow path pattern of a fluid through the porous substrate is described. The lateral flow assay device has a porous substrate matrix in fluid communication with a flow-rate control zone having a number of flow-rate control devices arranged as features in or on a substrate surface or laminates thereof in a body. The flow-rate control devices may include: a density gradient, porosity gradient, ion affinity gradient, micro-channels, and combinations thereof.Type: ApplicationFiled: December 18, 2008Publication date: June 24, 2010Inventors: Xuedong Song, Shawn R. Feaster, James M. Takeuchi, Kaiyuan Yang
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Publication number: 20100120644Abstract: There is provided a color change composition that remains stable in a single phase and that contains an indicator that produces an observable color change after a period of time to show that sufficient cleaning has been done or to indicate the thoroughness of the cleaning. This use indicating color change is useful for, for example, in soap for teaching children to wash their hands for a sufficient period of time. This composition may be added to many different base materials to indicate time of use or as a way to introduce enjoyment to the activity.Type: ApplicationFiled: January 22, 2010Publication date: May 13, 2010Applicant: KIMBERLY-CLARK WORLDWIDE, INC.Inventors: John Gavin MacDonald, Yanbin Huang, Kaiyuan Yang, Jaeho Kim, Ning Wei
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Patent number: 7713252Abstract: A therapeutic article includes a skin contact layer having a plurality of fibers forming a plurality of point-bearing surfaces configured for wear against a user's skin; a personal care composition disposed proximate the fibers; an external layer attached to the skin contact layer; and an intermediate layer interposed between the skin contact layer and the external layer, the intermediate layer being configured to activate the personal care composition, the external layer being configured to direct the activated personal care composition through the skin contact layer to treat the user.Type: GrantFiled: December 14, 2005Date of Patent: May 11, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Sharon L. Greene, Kaiyuan Yang, Shu-Ping Yang, Ning Wei, Jai Kyung, Jeffrey E. Fish
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Patent number: 7651989Abstract: There is provided a color change composition that remains stable in a single phase and that contains an indicator that produces an observable color change after a period of time to show that sufficient cleaning has been done or to indicate the thoroughness of the cleaning. This use indicating color change is useful for, for example, in soap for teaching children to wash their hands for a sufficient period of time. This composition may be added to many different base materials to indicate time of use or as a way to introduce enjoyment to the activity.Type: GrantFiled: August 29, 2003Date of Patent: January 26, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: John Gavin MacDonald, Yanbin Huang, Kaiyuan Yang, Jaeho Kim, Ning Wei
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Publication number: 20100015658Abstract: A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection region and a collection region. A blood sample meter is provided having a first end for absorption of a blood sample, a filtering section adjacent to the first end that filters red blood cell components from the blood sample, and a storage section adjacent to the filtering section that receives plasma or serum from the filtering section. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed in fluid communication with the collection region of the membrane. The plasma or serum is transferred from the storage section of the sample meter to the collection region of the membrane for subsequent migration to the detection region.Type: ApplicationFiled: September 30, 2009Publication date: January 21, 2010Applicant: KIMBERLY-CLARK WORLDWIDE, INCInventors: Kaiyuan Yang, Shawn R. Feaster, Ning Wei, Rosann M. Kaylor, Chibueze O. Chidebelu-Eze
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Patent number: 7618810Abstract: A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection region and a collection region. A blood sample meter is provided having a first end for absorption of a blood sample, a filtering section adjacent to the first end that filters red blood cell components from the blood sample, and a storage section adjacent to the filtering section that receives plasma or serum from the filtering section. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed in fluid communication with the collection region of the membrane. The plasma or serum is transferred from the storage section of the sample meter to the collection region of the membrane for subsequent migration to the detection region.Type: GrantFiled: December 14, 2005Date of Patent: November 17, 2009Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Kaiyuan Yang, Shawn R. Feaster, Ning Wei, Rosann M. Kaylor, Chibueze O. Chidebelu-Eze
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Patent number: 7552501Abstract: A finger cover, such as a finger wipe that can fit onto a human finger, is provided with an improved seam structure. The cover includes a pocket member having an open end for the insertion of a finger. The pocket member is formed by a first panel attached to a second panel along a flush outwardly facing circumferential edge seam. The seam is less than about 1 millimeter (mm) in width and about 1 mm in height. Additional reinforcing weld points may be provided at various locations along the seam.Type: GrantFiled: April 29, 2005Date of Patent: June 30, 2009Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Kaiyuan Yang, Jeffrey E. Fish, Shawn R. Feaster
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Patent number: 7549188Abstract: An oral cleaning device that can fit onto a human finger is provided. The oral cleaning device, or dental wipe, is at least partially made from an elastomeric material, such as an elastomeric nonwoven, so that the wipe can more aptly fit onto a finger. Furthermore, the wipe, in some instances, can possess a barrier that is liquid-impervious, but vapor-permeable so that the finger of a user is more comfortable during cleaning. Various additives can be applied to the wipe to aid in the cleaning process.Type: GrantFiled: October 18, 2005Date of Patent: June 23, 2009Inventors: Jason P. McDevitt, Michael S. Brunner, Jark C. Lau, Jaeho Kim, Kaiyuan Yang
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Publication number: 20090149925Abstract: A warming product (e.g., mask, glove, sock, etc.) configured to provide heat to the body part of a user is provided. The warming product contains a thermochromic composition that undergoes a color change at a certain temperature. The color change may signal to a user that the warming product is hot, thus providing an indication that the desired treatment is still functioning. Likewise, the color change may signal that the product is cool, thus providing an indication that the treatment is complete.Type: ApplicationFiled: December 5, 2007Publication date: June 11, 2009Applicant: KIMBERLY-CLARK WORLDWIDE, INC.Inventors: J. Gavin MacDonald, Kaiyuan Yang, Kelly D. Arehart
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Publication number: 20090149772Abstract: A cooling product (e.g., mask, glove, sock, etc.) configured to provide a cooling effect to the body part of a user is provided. The cooling product contains a thermochromic composition that undergoes a color change at a certain temperature. The color change may signal to a user that the cooling product is cold, thus providing an indication that the desired treatment is still functioning. Likewise, the color change may signal that the product is warm, thus providing an indication that the treatment is complete.Type: ApplicationFiled: December 5, 2007Publication date: June 11, 2009Applicant: KIMBERLY-CLARK WORLDWIDE, INC.Inventors: J. Gavin MacDonald, Kaiyuan Yang, Kelly D. Arehart
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Publication number: 20090124925Abstract: A technique for identifying a vein in a patient is disclosed. The technique involves the application of a thermochromic ink to a venous area on the skin of a patient (e.g., human or animal). The thermochromic ink comprises thermosensitive color-changing microcapsules that contain a proton-accepting chromogen and a desensitizer. The desensitizer possesses a melting point above which the chromogen is capable of becoming protonated, thereby resulting in a color change. Thereafter, the venous area is observed for the color change.Type: ApplicationFiled: November 13, 2007Publication date: May 14, 2009Applicant: KIMBERLY-CLARK WORLDWIDE, INC.Inventors: J. Gavin MacDonald, Kaiyuan Yang, Jaeho Kim, JungMo Kim
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Patent number: 7469427Abstract: A protective glove is provided made substantially from a laminate material. The laminate material includes a plurality of elastic strands. A first nonwoven web is attached to the plurality of elastic strands so that in a relaxed state of the elastic strands and the first nonwoven web at least one wrinkle is formed in the first nonwoven web. A second nonwoven web is also provided and is attached to the plurality of elastic strands so that in a relaxed state of the elastic strands and the second nonwoven web at least one wrinkle is formed in the second nonwoven web. The elastic strands, first nonwoven web and second nonwoven web form a laminate that is stretchable and permeable to liquid. A method of manufacture of a protective glove is also provided.Type: GrantFiled: June 30, 2005Date of Patent: December 30, 2008Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Kaiyuan Yang, Jeffrey E. Fish, Jason A. Baker, Oomman P. Thomas, Martin Shamis
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Publication number: 20080266117Abstract: Embodiments of the invention provide a sensor for detecting the presence of fluid in an absorbent article. The sensor may include a fluid activated battery. Fluid received in the absorbent article may connect electrodes of the fluid activated battery and cause a voltage to be generated between battery electrodes. The voltage generated between the electrodes may provide power to the sensor circuit. In one embodiment, the fluid activated battery may be configured to detect the presence of fluid in the absorbent article and the presence and/or amount of particular substances in the received fluid.Type: ApplicationFiled: April 30, 2007Publication date: October 30, 2008Inventors: Xuedong Song, James Matthew Takeuchi, Kaiyuan Yang, Shawn Jeffery Sullivan, Sridhar Ranganathan
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Patent number: 7390674Abstract: There is provided a lateral flow assay device for detecting the presence or quantity of an analyte residing in a test sample where the lateral flow assay device has a porous membrane in communication with a wicking pad. The porous membrane has a detection zone which has a chromophore configured to chemically react with an analyte or a secondary trigger or a reaction product from the analyte and a trigger generating reagent(s), to generate a visually detectible signal. Additional chrmophore zones may be located downstream from the first chrmophore zone to generate signals of varying color. Scavenging zones may be included between chromophore zones to attenuate the signal by reacting with the analyte without generating a visually detectable signal.Type: GrantFiled: March 14, 2005Date of Patent: June 24, 2008Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Shawn Ray Feaster, Kaiyuan Yang
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Publication number: 20080145272Abstract: A lateral flow assay device includes a housing, and a test strip disposed within the housing having a membrane with a detection region and a collection region. A sample meter includes a first end for absorption of a test sample, and a storage section that receives and stores at least a component of the test sample. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed adjacent the collection region of the membrane. The test sample component is transferable from the storagesection to the collection region for subsequent migration to the detection region. An activatable isolation mechanism is provided within the housing and is disposed so as to isolate portions of the sample meter storage section upon activation thereof such that a defined length of the storage section is presented to the collection region of the membrane.Type: ApplicationFiled: December 15, 2006Publication date: June 19, 2008Inventors: Shawn R. Feaster, Kaiyuan Yang, Ning Wei, Chibueze O. Chidebelu-Eze, James M. Takeuchi, Rosann M. Kaylor, Enrico L. DiGiammarino, Jeffrey E. Fish
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Publication number: 20080120761Abstract: Disclosed herein are thermal moderating donnable elastic articles suitable for a variety of uses. The thermal moderating donnable elastic articles include at least one thermal moderating elastic laminate material, the laminate including at least one polymeric elastic layer and at least one extensible fibrous layer, and the extensible fibrous layer including at least one thermal regulating additive. Such thermal moderating donnable elastic articles are useful for use in protective wear products, health care and medical care products, gloves, compressive bandages and comfort-providing wraps, and the like, and are capable of moderating temperature or providing temperature change sensation to the wearer's body part enveloped by the thermal moderating donnable elastic article. Also disclosed herein are thermal moderating elastic laminate materials having one or more thermally conductive additive materials.Type: ApplicationFiled: August 31, 2006Publication date: May 29, 2008Inventors: Kaiyuan Yang, Jason Alan Baker, Jeffrey E. Fish, Martin Shamis
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Publication number: 20080026484Abstract: A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. A sample membrane is utilized having a collection region and a detection region, the collection region having a known saturation volume for the intended test sample. A barrier is defined between the collection region and the detection region. The collection region is saturated with the test sample having a volume of less than about 100 microliters so that a known volume of the test sample is contained in the collection region. The barrier is removed from between the collection region and detection region of the membrane and a diluent is supplied to the collection region of the membrane to facilitate flow of the test sample from the collection region to the detection region of the membrane.Type: ApplicationFiled: October 5, 2007Publication date: January 31, 2008Inventors: James Takeuchi, Xuedong Song, Kaiyuan Yang, Ning Wei, Shawn Feaster