Patents by Inventor Kali Satya Bhujanga Rao ADIBHATLA

Kali Satya Bhujanga Rao ADIBHATLA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of pomalidomide and its purification
    Patent number: 11111228
    Abstract: The present invention is related to an improved process for the preparation of Pomalidomide with higher yields and high purity. Particularly the present invention relates to form A preparation of Pomalidomide and its purification. wherein the present process doesn't involve use of dioxane solvent and avoids higher temperatures.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: September 7, 2021
    Assignee: Natco Pharma Limited
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Dharmendher Ragidi, Uma Naresh Babu Kotra, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Modified process for the preparation of Ceritinib and amorphous form of Ceritinib
    Patent number: 10604505
    Abstract: The present invention is related to an improved process for the preparation of Ceritinib with high yield and high purity. The present process is cost effective and feasible in large scale production also. The present invention also related to a stable amorphous form of Ceritinib and its preparation. The present invention also relates to a process for the preparation of Crystalline form A of Ceritinib.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: March 31, 2020
    Assignee: Natco Pharma Limited
    Inventors: Durga Prasad Konakanchi, Subba Rao Pula, Muni Bhaskar Pallooru, Radha Rani Samatham, Ramakrishna Pilli, Lakshmana Viswa Venkata Pavan Kumar Maddula, Sandeep Karnam, Pulla Reddy Muddasani, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Pharmaceutical compositions comprising phenylaminopyrimidine derivative
    Patent number: 10383872
    Abstract: An oral pharmaceutical formulation containing an effective amount of NRC-AN-019 including its pharmaceutically acceptable salts and polymorphs thereof, by dispersing in a polymer system in a final state of subdivision to enhance oral bioavailability. It also relates to processes for the preparation of such compositions and using those compositions for the treatment of Chronic Myeloid Leukemia and other tumors such as head and neck cancer, prostate cancer and the like.
    Type: Grant
    Filed: January 30, 2016
    Date of Patent: August 20, 2019
    Assignee: NATCO PHARMA LTD
    Inventors: Durga Maheswari Parvataneni, Mitrabhanu Mohanty, Venkata Satyanarayana Appadwedula, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • PROCESS FOR THE PREPARATION OF POMALIDOMIDE AND ITS PURIFICATION
    Publication number: 20190233389
    Abstract: The present invention is related to an improved process for the preparation of Pomalidomide with higher yields and high purity. Particularly the present invention relates to form A preparation of Pomalidomide and its purification, wherein the present process doesn't involve use of dioxane solvent and avoids higher temperatures.
    Type: Application
    Filed: August 22, 2016
    Publication date: August 1, 2019
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Dharmendher Ragidi, Uma Naresh Babu Kotra, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Pharmaceutical compositions comprising phenylaminopyrimidine derivative
    Patent number: 10350209
    Abstract: An oral pharmaceutical formulation containing an effective amount of NRC-AN-019 including its pharmaceutically acceptable salts and polymorphs thereof, by dispersing in a polymer system in a final state of subdivision to enhance oral bioavailability. It also relates to processes for the preparation of such compositions and using those compositions for the treatment of Chronic Myeloid Leukemia and other tumors such as head and neck cancer, prostate cancer and the like.
    Type: Grant
    Filed: January 30, 2016
    Date of Patent: July 16, 2019
    Assignee: NATCO PHARMA LTD
    Inventors: Durga Maheswari Parvataneni, Mitrabhanu Mohanty, Venkata Satyanarayana Appadwedula, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • PHARMACEUTICAL COMPOSITIONS COMPRISING PHENYLAMINOPYRIMIDINE DERIVATIVE
    Publication number: 20190015412
    Abstract: An oral pharmaceutical formulation containing an effective amount of NRC-AN-019 including its pharmaceutically acceptable salts and polymorphs thereof, by dispersing in a polymer system in a final state of subdivision to enhance oral bioavailability. It also relates to processes for the preparation of such compositions and using those compositions for the treatment of Chronic Myeloid Leukemia and other tumors such as head and neck cancer, prostate cancer and the like.
    Type: Application
    Filed: January 30, 2016
    Publication date: January 17, 2019
    Inventors: Durga Maheswari PARVATANENI, Mitrabhanu MOHANTY, Venkata Satyanarayana APPADWEDULA, Kali Satya Bhujanga Rao ADIBHATLA, Venkaiah Chowdary NANNAPANENI
  • 7-(morpholinyl)-2-(N-piperazinyl) methyl thieno [2, 3-C] pyridine derivatives as anticancer drugs
    Patent number: 10106554
    Abstract: The present invention relates to novel series of substituted 7-(morpholinyl)-2-(N-piperazinyl)-methyl thieno [2, 3-c] pyridines of the following structure of formula I. Where in R1, R2, R3 and R4 are defined.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: October 23, 2018
    Assignee: NATCO PHARMA LIMITED
    Inventors: Durga Prasad Konakanchi, Subba Rao Pula, Rama Krishna Pilli, Lakshmana Viswa Venkata Pavan Kumar Maddula, Srinivasa Krishna Murthy Konduri, Janaki Rama Rao Ravi, Naga Vasanta Srinivasu Vuppalapati, Sandeep Kumar Thoota, Pulla Reddy Muddasani, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • 1H-1,8-naphthyridin-2-ones as anti proliferative compounds
    Patent number: 10047088
    Abstract: The present invention relates to novel antiproliferative 1H-1, 8-naphthyridin-2-ones of the general formula (I) or pharmaceutically acceptable salts thereof: In which the variable groups are as defined herein, and their preparation and use in therapeutic treatment of disorders related to inhibition of tyrosine kinases in warm blooded animals. The compounds can overcome imatinib induced drug resistance.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: August 14, 2018
    Assignee: NATCO PHARMA LIMITED
    Inventors: Amala Kompella, Venugopala Krishna Gampa, Srinivasulu Ganganamoni, Balakrishna Reddy Sirigireddy, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Anhydrous lenalidomide form-I
    Patent number: 10040778
    Abstract: Anhydrous polymorphic form-I of anti cancer drug, Lenalidomide whose chemical name is 3-(4-amino-1-oxo-1,3-dihydro-isoindole-2-yl)-piperidine-2,6-dione, is disclosed. Alternate methods for making anhydrous polymorphic form-I of Lenalidomide are also disclosed.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: August 7, 2018
    Assignee: NATCO PHARMA LIMITED
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Kotayya Babu Sikha, Chandrasekar Kandaswamy, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • 1H-1,8-NAPHTHYRIDIN-2-ONES AS ANTI PROLIFERATIVE COMPOUNDS
    Publication number: 20170349588
    Abstract: The present invention relates to novel antiproliferative 1H-1, 8-naphthyridin-2-ones of the general formula (I) or pharmaceutically acceptable salts thereof: In which the variable groups are as defined herein, and their preparation and use in therapeutic treatment of disorders related to inhibition of tyrosine kinases in warm blooded animals. The compounds can overcome imatinib induced drug resistance.
    Type: Application
    Filed: August 18, 2017
    Publication date: December 7, 2017
    Inventors: Amala KOMPELLA, Venugopala Krishna GAMPA, Srinivasulu GANGANAMONI, Balakrishna Reddy SIRIGIREDDY, Kali Satya Bhujanga Rao ADIBHATLA, Venkaiah Chowdary NANNAPANENI
  • 7-(MORPHOLINYL)-2-(N-PIPERAZINYL) METHYL THIENO [2, 3-C] PYRIDINE DERIVATIVES AS ANTICANCER DRUGS
    Publication number: 20170320891
    Abstract: The present invention relates to novel series of substituted 7-(morpholinyl)-2-(N-piperazinyl)-methyl thieno [2, 3-c] pyridines of the following structure of formula I. Where in R1, R2, R3 and R4 are defined.
    Type: Application
    Filed: December 11, 2014
    Publication date: November 9, 2017
    Inventors: Durga Prasad KONAKANCHI, Subba Rao PULA, Rama Krishna PILLI, Lakshmana Viswa Venkata Pavan Kumar MADDULA, Srinivasa Krishna Murthy KONDURI, Janaki Rama Rao RAVI, Naga Vasanta Srinivasu VUPPALAPATI, Sandeep Kumar THOOTA, Pulla Reddy MUDDASANI, Kali Satya Bhujanga Rao ADIBHATLA, Venkaiah Chowdary NANNAPANENI
  • 1H-1,8-naphthyridin-2ones as anti proliferative compounds
    Patent number: 9765072
    Abstract: The present invention relates to novel antiproliferative 1H-1, 8-naphthyridin-2-ones of the general formula (I) or pharmaceutically acceptable salts thereof: In which the variable groups are as defined herein, and their preparation and use in therapeutic treatment of disorders related to inhibition of tyrosine kinases in warm blooded animals. The compounds can overcome imatinib induced drug resistance.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: September 19, 2017
    Assignee: NATCO PHARMA LIMITED
    Inventors: Amala Kompella, Venugopala Krishna Gampa, Srinivasulu Ganganamoni, Balakrishna Reddy Sirigireddy, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Imatinib mesylate oral pharmaceutical composition and process for preparation thereof
    Patent number: 9750700
    Abstract: The invention relates to an oral pharmaceutical composition comprising, greater than 80% of Imatinib, by weight based on the total weight of the composition and the process for preparation thereof.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: September 5, 2017
    Assignee: Natco Pharma Limited
    Inventors: Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • 1H-1,8-NAPHTHYRIDIN-2ONES AS ANTI PROLIFERATIVE COMPOUNDS
    Publication number: 20170114057
    Abstract: The present invention relates to novel antiproliferative 1H-1,8-naphthyridin-2-ones of the general formula (I) or pharmaceutically acceptable salts thereof: In which the variable groups are as defined herein, and their preparation and use in therapeutic treatment of disorders related to inhibition of tyrosine kinases in warm blooded animals. The compounds can overcome imatinib induced drug resistance.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 27, 2017
    Inventors: Amala KOMPELLA, Venugopala Krishna GAMPA, Srinivasulu GANGANAMONI, Balakrishna Reddy SIRIGIREDDY, Kali Satya Bhujanga Rao ADIBHATLA, Venkaiah Chowdary NANNAPANENI
  • Fermentation process for the production of rapamycin
    Patent number: 9365880
    Abstract: The present invention provides a novel method for producing rapamycin by submerged fermentation which comprises cultivating Streptomyces hygroscopicus (CBS 773.72) and mutants thereof. The present invention provides a high yielding mutant culture MTCC5681 from Streptomyces hygroscopicus CBS 773.72. This culture is capable of producing rapamycin more efficiently than the cultures Streptomyces hygroscopicus from sources like ATCC, NRRL etc which have been reported so far.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: June 14, 2016
    Assignee: Natco Pharma Limited
    Inventors: Baby Rani Polavarapu, Suneel Kumar Battula, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • ANHYDROUS LENALIDOMIDE FORM-I
    Publication number: 20150353525
    Abstract: Anhydrous polymorphic form-I of anti cancer drug, Lenalidomide whose chemical name is 3-(4-amino-1-oxo-1,3-dihydro-isoindole-2-yl)-piperidine-2,6-dione, is disclosed. Alternate methods for making anhydrous polymorphic form-I of Lenalidomide are also disclosed.
    Type: Application
    Filed: July 8, 2015
    Publication date: December 10, 2015
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Kotayya Babu Sikha, Chandrasekar Kandaswamy, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Anhydrous lenalidomide form-I
    Patent number: 9108945
    Abstract: Anhydrous polymorphic form-I of anti cancer drug, Lenalidomide whose chemical name is 3-(4-amino-1-oxo-1,3-dihydro-isoindole-2-yl)-piperidine-2,6-dione, is disclosed. Alternate methods for making anhydrous polymorphic form-I of Lenalidomide are also disclosed.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: August 18, 2015
    Assignee: Natco Pharma Limited
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Kotayya Babu Sikha, Chandrasekar Kandaswamy, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • FERMENTATION PROCESS FOR THE PRODUCTION OF RAPAMYCIN
    Publication number: 20150079642
    Abstract: The present invention provides a novel method for producing rapamycin by submerged fermentation which comprises cultivating Streptomyces hygroscopicus (CBS 773.72) and mutants thereof. The present invention provides a high yielding mutant culture MTCC5681 from Streptomyces hygroscopicus CBS 773.72. This culture is capable of producing rapamycin more efficiently than the cultures Streptomyces hygroscopicus from sources like ATCC, NRRL etc which have been reported so far.
    Type: Application
    Filed: April 12, 2012
    Publication date: March 19, 2015
    Applicant: Natco Pharma Limited
    Inventors: Baby Rani Polavarapu, Suneel Kumar Battula, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • Anhydrous lenalidomide form-I
    Patent number: 8877932
    Abstract: Anhydrous polymorphic form-I of anti cancer drug, Lenalidomide whose chemical name is 3-(4-amino-1-oxo-1, 3-dihydro-isoindole-2-yl)-piperidine-2,6-dione, is disclosed. Alternate methods for making anhydrous polymorphic form-I of Lenalidomide are also disclosed.
    Type: Grant
    Filed: March 8, 2010
    Date of Patent: November 4, 2014
    Assignee: Natco Pharma Limited
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Kotayya Babu Sikha, Chandrasekar Kandaswamy, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni
  • ANHYDROUS LENALIDOMIDE FORM-I
    Publication number: 20140121245
    Abstract: Anhydrous polymorphic form-I of anti cancer drug, Lenalidomide whose chemical name is 3-(4-amino-1-oxo-1,3-dihydro-isoindole-2-yl)-piperidine-2,6-dione, is disclosed. Alternate methods for making anhydrous polymorphic form-I of Lenalidomide are also disclosed.
    Type: Application
    Filed: January 9, 2014
    Publication date: May 1, 2014
    Applicant: Natco Pharma Limited
    Inventors: Durga Prasad Konakanchi, Buchappa Gongalla, Kotayya Babu Sikha, Chandrasekar Kandaswamy, Kali Satya Bhujanga Rao Adibhatla, Venkaiah Chowdary Nannapaneni