Patents by Inventor Kalman G. Buki

Kalman G. Buki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for inhibition of retroviral replication
    Patent number: 6316495
    Abstract: A method for inhibition of retroviral replication by manipulation of enzyme adenosine diphosphoribosyl transferase which endogenously inhibits retroviral reverse transcriptase. The method is useful for prevention and treatment of retroviral infections, including HIV. The inhibition of the viral replication is achieved by administration to a mammal susceptible to or infected with a retrovirus drugs which specifically inhibit poly-ADP-ribosylation of adenosine diphosphoribosyl transferase.
    Type: Grant
    Filed: January 8, 1999
    Date of Patent: November 13, 2001
    Assignee: Octamer, Inc.
    Inventors: Ernest Kun, Kalman G. Buki
  • Method of treating malignant tumors with ketone thyroxine analogues having no significant hormonal activity
    Patent number: 5922775
    Abstract: The present invention provides methods for treating cancer, particularly malignant tumors, with ketone thyroxine analogues having no significant hormonal activity. A ketone thyroxine analogue is administered to an afflicted mammal in an amount effective to cause depression or regression of malignant tumor growth or to treat cancer. Particularly preferred ketone thyroxine analogues are those capable of causing about 35 percent or more inhibition of initial velocity of microtubule protein assembly in vitro.
    Type: Grant
    Filed: October 23, 1997
    Date of Patent: July 13, 1999
    Assignee: Octamer, Inc.
    Inventors: Ernestt Kun, Jerome Mendeleyev, Kalman G. Buki