Patents by Inventor Kalyanam Nagabhushanam

Kalyanam Nagabhushanam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of standardized composition of arjunoglucoside from the bark of
    Patent number: 10479749
    Abstract: Disclosed is a novel process for the isolation of bioactive compounds from Terminalia arjuna. More specifically, the invention discloses a process for isolation and enrichment of bioactive compounds Arjunic acid, Arjunolic acid, Arjungenin, Arjunetin, Arjunoglucoside-I, Arjunoglucoside-II, and Catechin from the bark of Terminalia arjuna. The invention also discloses a composition standardized to contain 3% arjunoglucosides isolated from the bark of Terminalia arjuna.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: November 19, 2019
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Beena Bhat
  • Functional nutritional blend for thermo-metabolic performance
    Patent number: 10477886
    Abstract: The present invention discloses a functional nutritional blend comprising Gynostemma pentaphyllum extract, Coleus forskohlii extract, Zingiber officinale extract and Piperine (Bioperine®), for increasing metabolic efficiency and inhibition of adipogenesis.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: November 19, 2019
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Mitchell Chavez
  • MODULATION OF IMMUNE FUNCTION BY BACILLUS COAGULANS
    Publication number: 20190328798
    Abstract: The present invention discloses a composition comprising heat inactivated spores and/or comprising heat inactivated vegetative cells of probiotic bacteria Bacillus coagulans, and a process for preparing the same. The invention also discloses a method of modulating immune function in mammals by activating macrophages, using a composition comprising Bacillus coagulans in the form of live or heat inactivated spore and/or vegetative cells.
    Type: Application
    Filed: April 29, 2019
    Publication date: October 31, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Furqan Ali, Sivakumar Arumugam, Shaheen Majeed, Lakshmi Mundkur, Anurag Pande
  • COMPOSITIONS FOR WEIGHT LOSS
    Publication number: 20190328818
    Abstract: The present invention discloses a composition comprising extracts of Cyperus rotundus, standardized to contain 3-5% w/w total stilbenes, extracts of Garcinia sp., standardized to contain 20% w/w garcinol and extracts of Coleus forskohlii standardized to contain not less than 10% w/w forskolin for the therapeutic management of diet induced obesity and weight gain and related conditions like liver dysfunction, NASH, NAFLD, liver cirrhosis, hypercholesterolemia, hyperlipidemia, kidney dysfunction by bringing about a reduction in body weight, increasing lean body mass and by normalizing the levels of liver enzymes, kidney markers and circulating lipids.
    Type: Application
    Filed: April 29, 2019
    Publication date: October 31, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Lakshmi Mundkur, Sarang Bani, Anjali Pandey
  • COMPOSITIONS CONTAINING TETRAHYDROCURCUMINOIDS FOR IMPROVEMENT OF ORAL HEALTH AND HYGIENE
    Publication number: 20190321308
    Abstract: Disclosed, is a novel composition containing tetrahydrocurcuminoids for the improvement of oral, health and hygiene. More specifically, disclosed is a novel composition of tetrahydrocurcuminoids and its application in the therapeutic management of canker sore and gingivitis.
    Type: Application
    Filed: April 18, 2018
    Publication date: October 24, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Shaheen Majeed
  • SKIN CARE COMPOSITIONS AND THEIR APPLICATIONS
    Publication number: 20190298641
    Abstract: The present invention discloses a synergistic composition comprising 3-O-ethyl-ascorbic acid and tetrahydrocurcuminoids for use as a skin lightening agent. The invention also discloses a method of inhibiting melanin biosynthesis and tyrosinase activity in mammalian skin cells using a composition comprising 3-O-ethyl-ascorbic acid and tetrahydrocurcuminoids.
    Type: Application
    Filed: April 2, 2019
    Publication date: October 3, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Lakshmi Mundkur
  • HYPOLIPIDEMIC EFFECTS OF COMPOSITIONS COMPRISING BETA-GLUCOGALLIN
    Publication number: 20190290671
    Abstract: Disclosed are the hypolipidemic effects of a composition comprising at least 10% w/w or above of 1-O-galloyl-?-D-glucose (?-glucogallin). The composition is effective in reducing the circulating levels of total cholesterol, triglycerides, LDL, cholesterol:HDL ratio and increasing HDL levels. The invention also discloses a method for reducing absorption and bio-accessibility of lipids in mammals using the abovementioned composition.
    Type: Application
    Filed: March 22, 2019
    Publication date: September 26, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Lakshmi Mundkur, Shaheen Majeed, Anurag Pande
  • LIVER PROTECTANT COMPOSITIONS AND THERAPEUTIC APPLICATIONS
    Publication number: 20190290599
    Abstract: The invention pertains to a composition comprising Curcuminoids and Garcinol for hepatoprotection. Specifically, the invention discloses a composition comprising 95% Curcuminoids and 20% Garcinol for the therapeutic management of Non-alcoholic fatty liver disease (NAFLD) and associated conditions like steatosis, Non-alcoholic steatoheapatitis (NASH), fibrosis and cirrhosis of the liver.
    Type: Application
    Filed: March 21, 2019
    Publication date: September 26, 2019
    Inventors: MUHAMMED MAJEED, KALYANAM NAGABHUSHANAM, LAKSHMI MUNDKUR
  • Process for the preparation of enantiopure 3-amino tetrahydrofuran and its salts
    Patent number: 10421734
    Abstract: Disclosed is simple, novel, scalable and environment friendly process for the preparation of enantiopure 3-amino tetrahydrofuran and its salts.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: September 24, 2019
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Savita Ganjihal, Rajendran Ramanujam
  • Process for synthesis of Oroxylin A
    Patent number: 10407401
    Abstract: Disclosed is a novel, simple, scalable and environment friendly process for the synthesis of Oroxylin A from Baicalin. Baicalin is esterified to obtain a methyl ester which is further selectively methylated to provide Oroxylin A glucuronide methyl ester which on de-glycosylation results in the formation of Oroxylin A.
    Type: Grant
    Filed: August 4, 2018
    Date of Patent: September 10, 2019
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Rajendran Ramanujam, Hosahalli Prabhakara Hemantha
  • MICROBIAL BIOCONVERSION OF CURCUMINOIDS TO CALEBIN-A
    Publication number: 20190264295
    Abstract: The present invention discloses a novel endophytic fungi, Ovatospora brasiliensis MTCC 25236 for the bioconversion of curcuminoids to Calebin-A and a method for its isolation from the rhizomes of Curcuma sp. The invention also discloses a method for the bioconversion of curcuminoids to Calebin-A using an endophytic fungi Ovatospora brasiliensis MTCC 25236 and bacterial species, Acinetobacter johnsonii and Pseudomonas putida.
    Type: Application
    Filed: February 21, 2019
    Publication date: August 29, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Anju Majeed, Nooruddin Thajuddin, Sivakumar Arumugam, Krishnamurthy Kulithalai Viswanathan, Samuel Thomas Manoharan, Furqan Ali, John Adams Sebastian, Jamsheeda Moothedath, Muthuraman Gnanamani, Kirankumar Beede
  • Hepatoprotective potential of Calebin A
    Publication number: 20190209509
    Abstract: The invention discloses a novel use of Calebin A in the prevention of hepatocellular damage. More specifically, the invention discloses the use of Calebin A in mitigating hepatocellular damage in drug and alcohol induced liver toxicity. The invention further discloses a method for the management of hyperglycemia, associated with drug and alcohol induced liver damage by increasing glucose uptake using Calebin A or a composition comprising Calebin A.
    Type: Application
    Filed: January 3, 2019
    Publication date: July 11, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Lakshmi Mundkur
  • COMPOSITIONS CONTAINING THYMOHYDROQUINONE AND THEIR METHOD OF PREPARATION
    Publication number: 20190192447
    Abstract: Disclosed are compositions enriched with thymohydroquinone, further comprising of thymoquinone, hederagenin and/or ?-hederin formulated by blending the active molecules isolated from the seeds of Nigella sativa. Also disclosed are novel processes for the isolation of bioactive components thymohydroquinone, thymoquinone from the seeds of Nigella sativa. A process for the isolation ?-hederin and hederagenin from the spent material of Nigella sativa is also disclosed herein.
    Type: Application
    Filed: December 26, 2018
    Publication date: June 27, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Beena Bhat
  • COMPOSITIONS FOR THE MANAGEMENT OF HYPERGLYCEMIA AND RELATED CONDITIONS
    Publication number: 20190192448
    Abstract: Disclosed is a method for therapeutic management of hyperglycemia in mammals using compositions containing thymohydroquinone. More specifically, the invention discloses compositions containing thymohydroquinone for inhibiting the activity of the enzyme ?-glucosidase and increasing the cellular uptake of glucose by mammalian cells. The anti-oxidant, anti-inflammatory and anti-glycation effects of thymohydroquinone are also disclosed herein.
    Type: Application
    Filed: December 26, 2018
    Publication date: June 27, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Lakshmi Mundkur
  • Process for enhancing the viable counts of lactic acid bacteria and useful compositions thereof
    Patent number: 10323227
    Abstract: Disclosed herein is a composition containing turmeric starch for use as a prebiotic plant fiber. Also disclosed is a method to increase the viable counts of Bacillus coagulans MTCC 5856 by co-culturing with turmeric starch and the production of short chain fatty acids (SCFA) by Bacillus coagulans MTCC 5856 using turmeric starch.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: June 18, 2019
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali
  • FUNCTIONAL NUTRITIONAL BLEND FOR THERMO-METABOLIC PERFORMANCE
    Publication number: 20190174810
    Abstract: The present invention discloses a functional nutritional blend comprising Gynostemma penlaphyllum extract, Coleus forskohlii extract, Zingiber officinale extract and Piperine (Bioperine®), for increasing metabolic efficiency and inhibition of adipogenesis.
    Type: Application
    Filed: February 21, 2019
    Publication date: June 13, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Mitchell Chavez
  • Process for enhancing the viable counts of lactic acid bacteria and useful compositions thereof
    Patent number: 10293008
    Abstract: Disclosed herein is (i) a method related to the growth promotional activity of plant based fibers on Bacillus coagulans MTCC 5856; (ii) the combination of plant based fibers and Bacillus coagulans MTCC 5856 to inhibit Gram Negative pathogenic bacteria; and (iii) the production of short chain fatty acids (SCFA) by Bacillus coagulans MTCC 5856 using plant based fibers.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: May 21, 2019
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali
  • Functional nutritional blend for thermo-metabolic performance
    Patent number: 10258073
    Abstract: The present invention discloses a functional nutritional blend comprising Gynostemma pentaphyllum extract, Coleus forskohlii extract, Zingiber officinale extract and piperine, for increasing metabolic efficiency and inhibition of adipogenesis.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: April 16, 2019
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Mitchell Chavez
  • PCR primers and methods thereof for the identification of bacillus coagulans
    Patent number: 10260112
    Abstract: The present invention discloses novel oligonucleotide primer sequences BC1, BC2 and BC3 for the identification of Bacillus coagulans. The invention also discloses a PCR based method for the identification of Bacillus coagulants using the aforesaid primers, wherein positive amplification with primer sets BC1, BC2 and negative amplification with primer set BC3 confirms the presence of Bacillus coagulans.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: April 16, 2019
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali
  • ALCOHOLIC BEVERAGE COMPOSITION CONTAINING BACILLUS COAGULANS
    Publication number: 20190085277
    Abstract: A probiotic-alcoholic beverage composition comprising Bacillus coagulans is disclosed herein wherein the said spore or vegetative cell of Bacillus coagulans exhibited high recovery, tolerability, compatibility and viability of spores and vegetative cells after brewing. Methods for brewing an alcoholic beverage composition comprising Bacillus coagulans wherein said spore or bacterium is added during pre-fermentation, during fermentation and post fermentation stages are also disclosed.
    Type: Application
    Filed: September 20, 2018
    Publication date: March 21, 2019
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali, Shaheen Majeed, Kirankumar Beede