Patents by Inventor Kam H. Leung

Kam H. Leung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process of enriching adherent CD4.sub.+ T cells from monocyte depleted peripheral blood mononuclear cells with interleukin 2 and interleukin 4
    Patent number: 5374549
    Abstract: Peripheral blood mononuclear cells (PBMC) are treated to deplete monocytes and the remaining cells are cultured in a medium containing interleukin-2 (IL-2) and interleukin-4 (IL-4). Nonadherent cells are removed and discarded, and adherent cells are further cultured in a medium of IL-2 and IL-4 which expands the CD4+ T cells population of the PBMC. The expanded, enriched CD4+T cells can be placed in a pharmaceutically acceptable carrier and administered to a mammal with IL-2 to treat a tumor.
    Type: Grant
    Filed: January 31, 1991
    Date of Patent: December 20, 1994
    Assignee: Terumo Corporation
    Inventor: Kam H. Leung
  • Protection of natural killer cell cytolytic activity in peripheral blood mononuclear cells
    Patent number: 5198334
    Abstract: Leucinol, phenylalaninol and benzamide protect against loss of Natural Killer activity when Peripheral Blood Mononuclear Cells are treated with an ester of an amino acid or dipeptide or an amide of an amino acid prior to incubation with IL-2 to generate Lymphokine-Activated Killer activity.
    Type: Grant
    Filed: July 21, 1989
    Date of Patent: March 30, 1993
    Assignee: Terumo Corporation
    Inventor: Kam H. Leung
  • Process for preparing lymphokine activated killer cells
    Patent number: 4849329
    Abstract: There are disclosed an improved process for preparing lymphokine activated killer (LAK) cells from peripheral blood mononuclear cells, a composition consisting essentially of the LAK cells prepared from the disclosed process in a pharmaceutically acceptable carrier, and a method of treating cancer comprising administering the disclosed composition to a patient suffering from said cancer.
    Type: Grant
    Filed: April 20, 1987
    Date of Patent: July 18, 1989
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Kam H. Leung, John J. Rinehart