Patents by Inventor Kam-Meng Wong

Kam-Meng Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and compositions for inhibiting tumorigenesis
    Publication number: 20050112707
    Abstract: The present invention relates to compounds, small interfering RNAs and compositions and methods of inhibiting tumorigenesis using agents that inhibit the sonic hedgehog and GLI signaling pathway, including agents that inhibit GLI expression, synthesis and/or function. The present invention also relates to particular biomarkers that can be used in the diagnosis and prognosis of cancer. Methods of treating cancer, including glioblastomas, medulloblastomas, basal cell carcinomas, prostate cancer and small cell and non-small cell lung cancer are also provided using small organic compounds, siRNAs and blocking antibodies that inhibit or block the SHH/GLI pathway.
    Type: Application
    Filed: August 31, 2004
    Publication date: May 26, 2005
    Inventors: Ariel Altaba, Pilar Sanchez, William Rom, Kam-Meng Wong