Patents by Inventor Kamal Azzaoui

Kamal Azzaoui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indol-alanine derivatives as selective S1P4-agonists
    Patent number: 7754896
    Abstract: The present invention relates to agonists of the S1P4 receptor, which are selective for the S1P4 receptor over one or more of the S1P1, S1P2, S1P3 or S1P5 receptors of at least 10 fold, in particular new indol-alanine derivatives of structure I, process for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them wherein R1 is phenyl or naphthyl, wherein phenyl is substituted by one or two of halogen, C1-6alkyl, C1-6alkoxy or phenylC1-6alkyl; and R2 is hydrogen or C1-6alkyl; in free or salt form.
    Type: Grant
    Filed: January 20, 2005
    Date of Patent: July 13, 2010
    Assignee: Novartis AG
    Inventors: Kamal Azzaoui, Rochdi Bouhelal, Peter Buehlmayer, Danilo Guerini, Manuel Koller
  • Indol-Alanine Derivatives as Selective S1P4-Agonists
    Publication number: 20090023797
    Abstract: The present invention relates to agonists of the S1P4 receptor, which are selective for the S1P4 receptor over one or more of the S1P1, S1P2, S1P3 or S1P5 receptors of at least 10 fold, in particular new indol-alanine derivatives of structure 1, process for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them wherein R1 is phenyl or naphthyl, wherein phenyl is substituted by one or two of halogen, C1-6alkyl, C1-6alkoxy or phenylC1-6alkyl; and R2 is hydrogen or C1-6alkyl; in free or salt form.
    Type: Application
    Filed: January 20, 2005
    Publication date: January 22, 2009
    Inventors: Kamal Azzaoui, Rochdi Bouhelal, Peter Buehlmayer, Danilo Guerini, Manuel Koller