Patents by Inventor Kamil Lotfali

Kamil Lotfali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of detecting a pathogen using a virus
    Patent number: 6436652
    Abstract: A bacteriophage linked to an enzyme can replace an antibody in a system for detecting the presence of a bacteria in a sample. Specifically Brucella abortus (a pathogen which causes brucellosis in cattle) can be detected using Brucella bacteriophage for the virus, urease for the enzyme linked to the bacteriophage, m-maleimidobenzoyl-N-hydrosysuccimide ester as a coupling reagent, sera from mice immunized with Brucella bacteriophage for a detector antibody, urease conjugated to anti-mouse sheep antibody for an indicator, and urea with bromcresol purple as the substrate. The materials can be used in indirect (sandwich) or direct enzyme-linked viral assays (ELVirA).
    Type: Grant
    Filed: August 18, 1999
    Date of Patent: August 20, 2002
    Assignee: Her Majesty the Queen in right of Canada, as represented by the Minister of National Defence of Her Majesty's Canadian Government
    Inventors: John W. Cherwonogrodzky, Kamil Lotfali
  • Method of detecting a pathogen using a virus
    Patent number: 6355445
    Abstract: A bacteriophage linked to an enzyme can replace an antibody in a system for detecting the presence of a bacteria in a sample. Specifically Brucella abortus (a pathogen which causes brucellosis in cattle) can be detected using Brucella bacteriophage for the virus, urease for the enzyme linked to the bacteriophage, m-maleimidobenzoyl-N-hydrosysuccimide ester as a coupling reagent, sera from mice immunized with Brucella bacteriophage for a detector antibody, urease conjugated to anti-mouse sheep antibody for an indicator, and urea with bromcresol purple as the substrate. The materials can be used in indirect (sandwich) or direct enzyme-linked viral assays (ELVirA).
    Type: Grant
    Filed: August 11, 1995
    Date of Patent: March 12, 2002
    Assignee: Her Majesty the Queen in right of Canada, as represented by the Minister of National Defence
    Inventors: John W. Cherwonogrodzky, Kamil Lotfali
  • METHOD OF DETECTING A PATHOGEN USING A VIRUS
    Publication number: 20010055780
    Abstract: A bacteriophage linked to an enzyme can replace an antibody in a system for detecting the presence of a bacteria in a sample. Specifically Brucella abortus (a pathogen which causes brucellosis in cattle) can be detected using Brucella bacteriophage for the virus, urease for the enzyme linked to the bacteriophage, m-maleimidobenzoyl-N-hydrosysuccimide ester as a coupling reagent, sera from mice immunized with Brucella bacteriophage for a detector antibody, urease conjugated to anti-mouse sheep antibody for an indicator, and urea with bromcresol purple as the substrate. The materials can be used in indirect (sandwich) or direct enzyme-linked viral assays (ELVirA).
    Type: Application
    Filed: August 11, 1995
    Publication date: December 27, 2001
    Inventors: JOHN W. CHERWONOGRODZKY, KAMIL LOTFALI