Patents by Inventor Kamil Paruch

Kamil Paruch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Publication number: 20070054925
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: March 31, 2006
    Publication date: March 8, 2007
    Inventors: Timothy Guzi, Kamil Paruch, Michael Dwyer, Ronald Doll, Viyyoor Girijavallabhan, Alan Mallams, Carmen Alvarez, Kartik Keertikar, Jocelyn Rivera, Tin-Yau Chan, Vincent Madison, Thierry Fischmann, Lawrence Dillard, Vinh Tran, Zhen He, Ray James, Haengsoon Park, Vidyadhar Paradkar, Douglas Hobbs
  • Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Publication number: 20070054906
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: March 31, 2006
    Publication date: March 8, 2007
    Inventors: Timothy Guzi, Kamil Paruch, Michael Dwyer, Ronald Doll, Viyyoor Girijavallabhan, Alan Mallams, Carmen Alvarez, Kartik Keertikar, Jocelyn Rivera, Tin-Yau Chan, Vincent Madison, Thierry Fischmann, Lawrence Dillard, Vinh Tran, Zhen He, Ray James, Haengsoon Park, Vidyadhar Paradkar, Douglas Hobbs
  • Imidazopyrazines as cyclin dependent kinase inhibitors
    Patent number: 7186740
    Abstract: In its many embodiments, the present invention provides a novel class of imidazo[1,2-a] pyrazine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: March 6, 2007
    Assignee: Schering Corporation
    Inventors: Kamil Paruch, Timothy J. Guzi, Michael P. Dwyer, Ronald J. Doll, Viyyoor M. Girijavallabhan
  • Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Publication number: 20070037824
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: September 3, 2003
    Publication date: February 15, 2007
    Inventors: Timothy Guzi, Kamil Paruch, Michael Dwyer, Ronald Doll, Viyyoor Girijavallabhan, Alan Mallams, Carmen Alvarez, Kartik Keertikar, Jocelyn Rivera, Tin-Yau Chan, Vincent Madison, Thierry Fischmann, Lawrence Dillard, Vinh Tran, Zhen He, Ray James, Haengsoon Park, Vidyadhar Paradkar, Douglas Hobbs
  • Pyrazolotriazines as kinase inhibitors
    Publication number: 20070032495
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]triazine compounds as inhibitors of kinases such as, for example, cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the kinases using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: October 12, 2006
    Publication date: February 8, 2007
    Inventors: Timothy Guzi, Kamil Paruch
  • Pyrazolotriazines as kinase inhibitors
    Patent number: 7166602
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]triazine compounds as inhibitors of kinases such as, for example, cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the kinases using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: January 19, 2006
    Date of Patent: January 23, 2007
    Assignee: Schering Corporation
    Inventors: Timothy J. Guzi, Kamil Paruch
  • Pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Patent number: 7161003
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: January 9, 2007
    Assignees: Schering Corporation, Pharmacopeia Drug Discovery, Inc.
    Inventors: Timothy J. Guzi, Kamil Paruch, Michael P. Dwyer, Ronald J. Doll, Viyyoor M. Girijavallabhan, Alan Mallams, Carmen S. Alvarez, Kartik M. Keertikar, Jocelyn Rivera, Tin-Yau Chan, Vincent Madison, Thierry O. Fischmann, Lawrence W. Dillard, Vinh D. Tran, Zhen Min He, Ray Anthony James, Haengsoon Park, Vidyadhar M. Paradkar, Douglas Walsh Hobbs
  • Pyrazolopyridines as cyclin dependent kinase inhibitors
    Patent number: 7151104
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyridine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: September 17, 2003
    Date of Patent: December 19, 2006
    Assignee: Schering Corporation
    Inventors: Michael P. Dwyer, Timothy J. Guzi, Kamil Paruch, Ronald J. Doll, Kartik M. Keertikar, Viyyoor M. Girijavallabhan
  • 17 ?-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Patent number: 7138396
    Abstract: There are disclosed compounds of the formula (I): prodrugs thereof, or pharmaceutically acceptable salts of the compounds or of said prodrugs which are useful as inhibitors of Type 3 17?-Hydroxysteroid Dehydrogenase. Also disclosed are pharmaceutical compositions containing said compounds and their use for the treatment or prevention of androgen dependent diseases.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: November 21, 2006
    Assignee: Schering Corporation
    Inventors: Timothy J. Guzi, Kamil Paruch, Alan K. Mallams, Jocelyn D. Rivera, Ronald J. Doll, Viyyoor M. Girijavallabhan, Jonathan A. Pachter, Yi-Tsung Liu, Anil K. Saksena
  • Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Publication number: 20060235025
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: March 31, 2006
    Publication date: October 19, 2006
    Inventors: Timothy Guzi, Kamil Paruch, Michael Dwyer, Ronald Doll, Viyyoor Girijavallabhan, Lawrence Dillard, Vinh Tran, Zhen He, Ray James, Haengsoon Park
  • Pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Patent number: 7119200
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: February 11, 2004
    Date of Patent: October 10, 2006
    Assignees: Schering Corporation, Pharmacopeia Drug Discovery, Inc.
    Inventors: Timothy J. Guzi, Kamil Paruch, Michael P. Dwyer, Ronald J. Doll, Viyyoor M. Girijavallabhan, Alan Mallams, Carmen S. Alvarez, Kartik M. Keertikar, Jocelyn Rivera, Tin-Yau Chan, Vincent Madison, Thierry O. Fischmann, Lawrence W. Dillard, Vinh D. Tran, Zhen Min He, Ray Anthony James, Haengsoon Park, Vidyadhar M. Hobbs, Douglas Walsh Hobbs
  • Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Publication number: 20060178371
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: March 31, 2006
    Publication date: August 10, 2006
    Inventors: Timothy Guzi, Kamil Paruch, Michael Dwyer, Ronald Doll, Viyyoor Girijavallabhan, Carmen Alvarez, Tin-Yau Chan, Chad Knutson, Vincent Madison, Thierry Fischmann, Lawrence Dillard, Vinh Tran, Zhen He, Ray James, Haengsoon Park
  • Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Publication number: 20060173017
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: March 31, 2006
    Publication date: August 3, 2006
    Inventors: Timothy Guzi, Kamil Paruch, Michael Dwyer, Ronald Doll, Viyyoor Girijavallabhan, Chad Knutson, Brian McKittrick, Lawrence Dillard, Vinh Tran, Zhen Min He, Ray James, Haengsoon Park
  • Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Publication number: 20060173016
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: March 31, 2006
    Publication date: August 3, 2006
    Inventors: Timothy Guzi, Kamil Paruch, Michael Dwyer, Ronald Doll, Viyyoor Girijavallabhan, Lawrence Dillard, Vinh Tran, Zhen He, Ray James, Haengsoon Park
  • Pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Patent number: 7084271
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: August 1, 2006
    Assignees: Schering Corporation, Pharmacopeia Drug Discovery, Inc.
    Inventors: Timothy J. Guzi, Kamil Paruch, Michael P. Dwyer, Ronald J. Doll, Viyyoor M. Girijavallabhan, Chad Knutson, Brian McKittrick, Lawrence W. Dillard, Vinh D. Tran, Zhen Min He, Ray Anthony James, Haengsoon Park
  • Pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Patent number: 7078525
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: July 18, 2006
    Assignees: Schering Corporation, Pharmacopeia Drug Discovery, Inc.
    Inventors: Timothy J. Guzi, Kamil Paruch, Michael P. Dwyer, Ronald J. Doll, Viyyoor M. Girijavallabhan, Lawrence W. Dillard, Vinh D. Tran, Zhen Min He, Ray Anthony James, Haengsoon Park
  • 17?-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Patent number: 7074795
    Abstract: In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17 ?-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with type 3 17 ?-hydroxysteroid dehydrogenase using such compounds or pharmaceutical compositions. In one embodiment, the present invention discloses a compound having the general structure shown in Formula I: wherein the various moieties are as defined herein.
    Type: Grant
    Filed: November 14, 2003
    Date of Patent: July 11, 2006
    Assignee: Schering Corporation
    Inventors: Kamil Paruch, Timothy J. Guzi
  • Pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Patent number: 7074924
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: July 11, 2006
    Assignees: Schering Corporation, Pharmacopeia Drug Discovery, Inc.
    Inventors: Timothy J. Guzi, Kamil Paruch, Michael P. Dwyer, Ronald J. Doll, Viyyoor M. Girijavallabhan, Lawrence W. Dillard, Vinh D. Tran, Zhen Min He, Ray Anthony James, Haengsoon Park
  • 17Beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Publication number: 20060148816
    Abstract: In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17?-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with type 3 17?-hydroxysteroid dehydrogenase using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: February 24, 2006
    Publication date: July 6, 2006
    Inventors: Kamil Paruch, Timothy Guzi
  • Pyrazolopyrimidines as cyclin dependent kinase inhibitors
    Patent number: 7067661
    Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: June 27, 2006
    Assignees: Schering Corporation, Pharmacopeia Drug Discovery, Inc.
    Inventors: Timothy J. Guzi, Kamil Paruch, Michael P. Dwyer, Ronald J. Doll, Viyyoor M. Girijavallabhan, Carmen S. Alvarez, Tin-Yau Chan, Chad Knutson, Vincent Madison, Thierry O. Fischmann, Lawrence W. Dillard, Vinh D. Tran, Zhen Min He, Ray Anthony James, Haengsoon Park