Abstract: Provided are methods for analyzing and purifying degarelix or a pharmaceutically acceptable salt thereof containing at least one related impurity. Also provided are methods for analyzing and purifying degarelix or a pharmaceutically acceptable salt thereof containing compound A and/or compound D as an impurity. Further provided are degarelix or a pharmaceutically acceptable salt thereof prepared from and/or selected using the disclosed methods.

Abstract: The present invention relates to liquid pharmaceutical composition suitable for oral administration comprising clonidine or pharmaceutically acceptable salts thereof with at least one buffer and at least one preservative. The present invention also relates to process for preparing the said liquid pharmaceutical composition.

Abstract: Provided herein are methods of producing carbon-based compounds from the fermentation of cellulosic feedstocks. In certain embodiments, the cellulosic feedstock and/or source of the cellulosic feedstock is grass, guar gum, leaves, cattails, and/or phragmites.

Abstract: The invention provides a method for analyzing a protamine sample for the presence or amount of at least one nucleotidic impurity. The invention also provides a method for the quantitation of peptides in a sample of protamine comprising four major peptides and at least one related impurity.

Abstract: The present invention relates to liquid pharmaceutical composition suitable for oral administration comprising clonidine or pharmaceutically acceptable salts thereof with at least one buffer and at least one preservative. The present invention also relates to process for preparing the said liquid pharmaceutical composition.

Abstract: A coaxial connector locking bracket supports a connection between a coaxial connector and a corresponding mating connector. The locking bracket includes a locking member at one end configured to engage a coupling nut of the coaxial connector and an attachment at an opposite end configured to fix a location of the locking bracket relative to the coaxial connector. The fixed location of the locking bracket is to prevent the coupling nut from rotating about an axis of the coaxial connector. The locking bracket further includes a body connected between the locking member and the attachment.

Abstract: The invention provides a method for analyzing a protamine sample for the presence or amount of at least one nucleotidic impurity. The invention also provides a method for the quantitation of peptides in a sample of protamine comprising four major peptides and at least one related impurity.

Abstract: The invention provides a method for analyzing a protamine sample for the presence or amount of at least one nucleotidic impurity. The invention also provides a method for the quantitation of peptides in a sample of protamine comprising four major peptides and at least one related impurity.

Abstract: A coaxial connector locking bracket supports a connection between a coaxial connector and a corresponding mating connector. The locking bracket includes a locking member at one end configured to engage a coupling nut of the coaxial connector and an attachment at an opposite end configured to fix a location of the locking bracket relative to the coaxial connector. The fixed location of the locking bracket is to prevent the coupling nut from rotating about an axis of the coaxial connector. The locking bracket further includes a body connected between the locking member and the attachment.

Abstract: A system for enhancing a nucleic acid sample may include a one pump, a denaturing chamber; a microfluidic hydroxyapatite chromatography device configured for performing hydroxyapatite chromatography on the nucleic acid sample, a sample collector, and tubing connecting the pump with the denaturing chamber, the hydroxyapatite chromatography device and the sample collector such that the pump may be used to move the nucleic acid sample from the denaturing chamber to the hydroxyapatite chromatography device and then to the sample collector.

Abstract: The invention provides a method for analyzing a protamine sample for the presence or amount of at least one nucleotidic impurity. The invention also provides a method for the quantitation of peptides in a sample of protamine comprising four major peptides and at least one related impurity.

Abstract: A multi-pair cable having a double jacket, including an inner jacket and an outer jacket. The inner and outer jackets each including channels formed on an inner surface. The channeled double jacket of the cable reducing the occurrence of alien crosstalk between adjacent cables by reducing the overall dielectric constant of the cable and increasing the center-to-center distance between adjacent cables. The channeled double jacket of the cable still accommodating existing standard cable connectors.

Abstract: A multi-pair cable having a double jacket, including an inner jacket and an outer jacket. The inner and outer jackets each including channels formed on an inner surface. The channeled double jacket of the cable reducing the occurrence of alien crosstalk between adjacent cables by reducing the overall dielectric constant of the cable and increasing the center-to-center distance between adjacent cables. The channeled double jacket of the cable still accommodating existing standard cable connectors.

Abstract: A multi-pair cable having a double jacket, including an inner jacket and an outer jacket. The inner and outer jackets each including channels formed on an inner surface. The channeled double jacket of the cable reducing the occurrence of alien crosstalk between adjacent cables by reducing the overall dielectric constant of the cable and increasing the center-to-center distance between adjacent cables. The channeled double jacket of the cable still accommodating existing standard cable connectors.

Abstract: A multi-pair cable having a double jacket, including an inner jacket and an outer jacket. The inner and outer jackets each including channels formed on an inner surface. The channeled double jacket of the cable reducing the occurrence of alien crosstalk between adjacent cables by reducing the overall dielectric constant of the cable and increasing the center-to-center distance between adjacent cables. The channeled double jacket of the cable still accommodating existing standard cable connectors.

Abstract: The present invention relates to novel compositions containing the NK3 receptor antagonist talnetant which compositions have enhanced bioavailability. In addition, the invention relates to processes for the preparation and to uses of the compositions in therapy.

Abstract: An apparatus that couples automated injection with flow feedback to provide nanoliter accuracy in controlling microliter volumes. The apparatus comprises generally a source of hydraulic fluid pressure, a fluid isolator joined to the outlet of the hydraulic pressure source and a flow sensor to provide pressure-driven analyte metering. For operation generally and particularly in microfluidic systems the hydraulic pressure source is typically an electrokinetic (EK) pump that incorporates gasless electrodes. The apparatus is capable of metering sub-microliter volumes at flowrates of 1-100 ?L/min into microsystem load pressures of up to 1000-50 psi, respectively. Flowrates can be specified within 0.5 ?L/min and volumes as small as 80 nL can be metered.

Abstract: Disclosed is a water-dispersible solid composition of a sparingly water-soluble compound in a particulatable lipidic carrier, methods for the preparation and use of the same. The compositions of this intention provide improved solubility and dissolution characteristics and enhanced bioavailability of the sparingly soluble compound.

Abstract: The present invention provides a method for recovering a mismatch between a media gateway (MGW) and a media gateway controller (MGC). The MGC believes that a channel is idle and attempts to assign the channel in a bearer connection. The state information of the MGW indicates that the channel is busy. In response to a message indicating that the channel assignment failed from the MGW, the MGC sends a subtract message to the MGW to locate the termination and release that resource by returning the termination to an idle state. At this point the state of the channel has been resynchronized between the MGW and the MGC. The MGW then removes all endpoints associated with the context to release the resource from all contexts and bearer connections.

Abstract: A method for altering the surface properties of a particle bed. In application, the method pertains particularly to an electrokinetic pump configuration where nanoparticles are bonded to the surface of the stationary phase to alter the surface properties of the stationary phase including the surface area and/or the zeta potential and thus improve the efficiency and operating range of these pumps. By functionalizing the nanoparticles to change the zeta potential the electrokinetic pump is rendered capable of operating with working fluids having pH values that can range from 2-10 generally and acidic working fluids in particular. For applications in which the pump is intended to handle highly acidic solutions latex nanoparticles that are quaternary amine functionalized can be used.