Patents by Inventor Kan Lam

Kan Lam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7470437
    Abstract: Methods of treating conditions with a metal-containing material are disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: December 30, 2008
    Assignee: Nucryst Pharmaceuticals Corp.
    Inventors: Robert E. Burrell, John B. Wright, Kan Lam, Antony G. Naylor, Peter H. Moxham, Scott H. Gillis, Paul Schechter
  • Patent number: 7078060
    Abstract: Solutions and aerosols of metal-containing compounds are disclosed. Methods of preparing and using the solutions and aerosols, particularly in the treatment of a subject having a condition, are also disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.
    Type: Grant
    Filed: February 12, 2003
    Date of Patent: July 18, 2006
    Assignee: Nucryst Pharmaceuticals Corp.
    Inventors: Robert E. Burrell, John B. Wright, Kan Lam, Hua Qing Yin, Antony G. Naylor, Peter H. Moxham, Scott H. Gillis, Paul Schechter
  • Patent number: 7001617
    Abstract: The invention relates to a method to induce apoptosis and to inhibit matrix metalloproteinases in a disease condition in a human or animal by contacting hyperplastic tissue, tumor tissue, or a cancerous lesion with one or more antimicrobial metals, preferably formed with atomic disorder, and preferably in a nanocrystalline form. In another aspect of the invention, there is provided a method of preventing excessive release of matrix metalloproteinases from an inflammatory cell in a disease condition in a human or an animal by contacting the cell with a therapeutically effective amount of a noble metal in a crystalline form characterized by atomic disorder, or with a solution derived therefrom to provide a modulatory effect on one or more matrix metalloproteinases, wherein the one or more noble metals is formed with atomic disorder, and preferably in a nanocrystalline form.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: February 21, 2006
    Assignee: Nueryst Pharmaceuticals Corp.
    Inventors: Robert Edward Burrell, John Barrymore Wright, Kan Lam
  • Publication number: 20050129624
    Abstract: Methods of treating conditions with a metal-containing material are disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.
    Type: Application
    Filed: November 10, 2004
    Publication date: June 16, 2005
    Applicant: Nucryst Pharmaceuticals Corp.
    Inventors: Robert Burrell, Scott Gillis, Paul Schechter, Antony Naylor, Peter Moxham, John Wright, Kan Lam
  • Publication number: 20040191329
    Abstract: Compositions and methods of metal-containing materials of metal-containing materials are disclosed. The metal-containing material can be, for example, an antimicrobial material, an anti-biofilm material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, anti-proliferative, MMP modulating material, an atomically disordered, crystalline material, and/or a nanocrystalline material. In certain embodiments, the metal-containing material is an atomically disordered, nanocrystalline silver-containing material.
    Type: Application
    Filed: October 22, 2003
    Publication date: September 30, 2004
    Inventors: Robert E. Burrell, John B. Wright, Kan Lam, Hua Qing Yin, Antony G. Naylor, Peter H. Moxham, Scott H. Gillis, Paul Schechter, James Alexander Robert Stiles
  • Patent number: 6692773
    Abstract: The invention relates to the use of one or more noble metals selected from silver, gold, platinum, and palladium but most preferably silver, in a nanocrystalline form, for the treatment of a hyperproliferative skin disorder or disease such as psoriasis. Among the noble metals, silver is preferred for such treatment. The nanocrystalline noble metal of choice may be used in the form of a nanocrystalline coating of one or more noble metals, a nanocrystalline powder of one or more noble metals, or a solution containing dissolved species from a nanocrystalline powder or coating of one or more noble metals.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: February 17, 2004
    Assignee: Nucryst Pharmaceuticals Corp.
    Inventors: Robert Edward Burrell, John Barrymore Wright, Kan Lam
  • Publication number: 20030206966
    Abstract: Methods of inducing apoptosis and modulating metalloproteinases, particularly with metal-containing compounds, are disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.
    Type: Application
    Filed: October 22, 2002
    Publication date: November 6, 2003
    Inventors: Robert E. Burrell, Scott H. Gillis, Paul Schechter, John B. Wright, Kan Lam
  • Publication number: 20030203046
    Abstract: Solutions and aerosols of metal-containing compounds are disclosed. Methods of preparing and using the solutions and aerosols, particularly in the treatment of a subject having a condition, are also disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.
    Type: Application
    Filed: February 12, 2003
    Publication date: October 30, 2003
    Inventors: Robert E. Burrell, Scott H. Gillis, Paul Schechter, John B. Wright, Kan Lam, Hua Qing Yin, Antony G. Naylor, Peter H. Moxham
  • Publication number: 20030194444
    Abstract: Methods of treating skin and integument conditions, particularly with metal-containing compounds, are disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.
    Type: Application
    Filed: October 22, 2002
    Publication date: October 16, 2003
    Inventors: Robert E. Burrell, Scott H. Gillis, Paul Schechter, John B. Wright, Kan Lam, Hua Qing Yin
  • Publication number: 20030185901
    Abstract: Methods of treating conditions with a metal-containing material are disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.
    Type: Application
    Filed: October 22, 2002
    Publication date: October 2, 2003
    Inventors: Robert E. Burrell, Scott H. Gillis, Paul Schechter, Antony G. Naylor, Peter H. Moxham, John B. Wright, Kan Lam
  • Publication number: 20030180379
    Abstract: Solutions and aerosols of metal-containing compounds are disclosed. Methods of preparing and using the solutions and aerosols, particularly in the treatment of a subject having a condition, are also disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.
    Type: Application
    Filed: October 22, 2002
    Publication date: September 25, 2003
    Inventors: Robert E. Burrell, Scott H. Gillis, Paul Schechter, John B. Wright, Kan Lam, Hua Qing Yin, Antony G. Naylor, Peter H. Moxham
  • Publication number: 20030170314
    Abstract: Compositions of metal-containing compounds are disclosed. Methods of preparing and using the compositions, particularly in the treatment of a subject having a condition, are also disclosed. The metal-containing material can be, for example, an antimicrobial material, an antibacterial material, an anti-inflammatory material, an anti-fungal material, an anti-viral material, an anti-cancer material, a pro-apoptosis material, and/or an MMP modulating material. In certain embodiments, the metal-containing material is an atomically disordered, silver-containing material.
    Type: Application
    Filed: October 22, 2002
    Publication date: September 11, 2003
    Inventors: Robert E. Burrell, Scott H. Gillis, Paul Schechter, John B. Wright, Kan Lam, Hua Qing Yin, Antony G. Naylor, Peter H. Moxham
  • Publication number: 20030072810
    Abstract: The invention relates to a method to induce apoptosis and to inhibit matrix metalloproteinases in a disease condition in a human or animal by contacting hyperplastic tissue, tumor tissue, or a cancerous lesion with one or more antimicrobial metals, preferably formed with atomic disorder, and preferably in a nanocrystalline form. In another aspect of the invention, there is provided a method of preventing excessive release of matrix metalloproteinases from an inflammatory cell in a disease condition in a human or an animal by contacting the cell with a therapeutically effective amount of a noble metal in a crystalline form characterized by atomic disorder, or with a solution derived therefrom to provide a modulatory effect on one or more matrix metalloproteinases, wherein the one or more noble metals is formed with atomic disorder, and preferably in a nanocrystalline form.
    Type: Application
    Filed: May 30, 2002
    Publication date: April 17, 2003
    Inventors: Robert Edward Burrell, John Barrymore Wright, Kan Lam
  • Publication number: 20030021854
    Abstract: The invention relates to a method to induce apoptosis and to inhibit matrix metalloproteinases in a disease condition in a human or animal by contacting hyperplastic tissue, tumor tissue, or a cancerous lesion with one or more antimicrobial metals, preferably formed with atomic disorder, and preferably in a nanocrystalline form. The nanocrystalline antimicrobial metal of choice may be used in the form of a nanocrystalline coating of one or more antimicrobial metals, a nanocrystalline powder of one or more antimicrobial metals, or a solution containing dissolved species from a nanocrystalline powder or coating of one or more antimicrobial metals.
    Type: Application
    Filed: April 23, 2002
    Publication date: January 30, 2003
    Inventors: Robert Edward Burrell, John Barrymore Wright, Kan Lam
  • Publication number: 20020051824
    Abstract: The invention relates to the use of one or more noble metals selected from silver, gold, platinum, and palladium but most preferably silver, in a nanocrystalline form, for the treatment of a hyperproliferative skin disorder or disease such as psoriasis. Among the noble metals, silver is preferred for such treatment. The nanocrystalline noble metal of choice may be used in the form of a nanocrystalline coating of one or more noble metals, a nanocrystalline powder of one or more noble metals, or a solution containing dissolved species from a nanocrystalline powder or coating of one or more noble metals.
    Type: Application
    Filed: July 27, 2001
    Publication date: May 2, 2002
    Inventors: Robert Edward Burrell, John Barrymore Wright, Kan Lam