Patents by Inventor Kanaka Pattabiraman

Kanaka Pattabiraman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase
    Patent number: 9169224
    Abstract: Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: October 27, 2015
    Assignee: Janssen Pharmaceutica NV
    Inventors: Richard Apodaca, J. Guy Breitenbucher, Kanaka Pattabiraman, Mark Seierstad, Wei Xiao
  • PIPERAZINYL AND PIPERIDINYL UREAS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE
    Publication number: 20130331396
    Abstract: Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
    Type: Application
    Filed: August 13, 2013
    Publication date: December 12, 2013
    Applicant: Janssen Pharmaceutica NV
    Inventors: Richard Apodaca, J. Guy Breitenbucher, Kanaka Pattabiraman, mark Seierstad, Wei Xiao
  • Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase
    Patent number: 8530476
    Abstract: Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: September 10, 2013
    Assignee: Janssen Pharmaceutica NV
    Inventors: Richard Apodaca, J. Guy Breitenbucher, Kanaka Pattabiraman, Mark Seierstad, Wei Xiao
  • Derivatives of urea and related diamines, methods for their manufacture, and uses therefor
    Patent number: 8324396
    Abstract: The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders related to the function of the calcium sensing receptor. The invention also relates to processes for making such compounds and to intermediates useful in these processes.
    Type: Grant
    Filed: July 10, 2008
    Date of Patent: December 4, 2012
    Assignee: Amgen Inc.
    Inventors: Pierre Deprez, Christopher Fotsch, Paul Harrington, Sarah Lively, Kanaka Pattabiraman, David St. Jean, Taoues Temal-Laib
  • PIPERAZINYL AND PIPERIDINYL UREAS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE
    Publication number: 20100004261
    Abstract: Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
    Type: Application
    Filed: September 11, 2009
    Publication date: January 7, 2010
    Inventors: Richard Apodaca, J. Guy Breitenbucher, Kanaka Pattabiraman, Mak Seierstad, Wei Xiao
  • Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase
    Patent number: 7598249
    Abstract: Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
    Type: Grant
    Filed: December 29, 2005
    Date of Patent: October 6, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Richard Apodaca, J. Guy Breitenbucher, Kanaka Pattabiraman, Mark Seierstad, Wei Xiao
  • N-heteroarylpiperazinyl ureas as modulators of fatty acid amide hydrolase
    Patent number: 7541359
    Abstract: Certain N-heteroarylpiperazinyl urea compounds of Formula (I), as defined in the specification, are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: June 2, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Richard Apodaca, J. Guy Breitenbucher, Kanaka Pattabiraman, Mark Seierstad, Wei Xiao
  • Derivatives of urea and related diamines, methods for their manufacture, and uses therefor
    Publication number: 20090054463
    Abstract: The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders related to the function of the calcium sensing receptor. The invention also relates to processes for making such compounds and to intermediates useful in these processes.
    Type: Application
    Filed: July 10, 2008
    Publication date: February 26, 2009
    Inventors: Pierre Deprez, Christopher Fotsch, Paul Harrington, Sarah Lively, Kanaka Pattabiraman, David St. Jean, Taoues Temal-Laib
  • Guanidinium transport reagents and conjugates
    Patent number: 7169814
    Abstract: Transport reagents and conjugates of therapeutic agents linked to transport reagents are described. In particular, the transport reagents have a plurality of guanidinium moieties that are either contiguous or spaced along a backbone, but are sufficiently removed from the backbone via tethers, to allow their interaction with a cell or tissue surface, leading to uptake of the therapeutic agent.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: January 30, 2007
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Cellgate, Inc.
    Inventors: Jonathan B. Rothbard, Paul A. Wender, Kanaka Pattabiraman, Erin T. Pelkey, Theodore C. Jessop
  • N-heteroarylpiperazinyl ureas as modulators of fatty acid amide hydrolase
    Publication number: 20070004741
    Abstract: Certain N-heteroarylpiperazinyl urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
    Type: Application
    Filed: June 28, 2006
    Publication date: January 4, 2007
    Inventors: Richard Apodaca, J. Breitenbucher, Kanaka Pattabiraman, Mark Seierstad, Wei Xiao
  • Bi-directional synthesis of oligoguanidine transport agents
    Publication number: 20060264608
    Abstract: Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ?-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.
    Type: Application
    Filed: March 14, 2006
    Publication date: November 23, 2006
    Inventors: Paul Wender, Christopher VanDeusen, Kanaka Pattabiraman, Erin Pelkey, Theodore Jessop
  • Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase
    Publication number: 20060173184
    Abstract: Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).
    Type: Application
    Filed: December 29, 2005
    Publication date: August 3, 2006
    Inventors: Richard Apodaca, J. Breitenbucher, Kanaka Pattabiraman, Mark Seierstad, Wei Xiao
  • Bi-directional synthesis of oligoguanidine transport agents
    Patent number: 7067698
    Abstract: Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ?-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: June 27, 2006
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Paul A. Wender, Christopher L. VanDeusen, Kanaka Pattabiraman, Erin T. Pelkey, Theodore C. Jessop
  • Guanidinium transport reagents and conjugates
    Publication number: 20040161405
    Abstract: Transport reagents and conjugates of therapeutic agents linked to transport reagents are described. In particular, the transport reagents have a plurality of guanidinium moieties that are either contiguous or spaced along a backbone, but are sufficiently removed from the backbone via tethers, to allow their interaction with a cell or tissue surface, leading to uptake of the therapeutic agent.
    Type: Application
    Filed: December 11, 2002
    Publication date: August 19, 2004
    Inventors: Jonathan B. Rothbard, Paul A. Wender, Kanaka Pattabiraman, Erin T. Pelkey, Theodore C. Jessop
  • Guanidinium transport reagents and conjugates
    Publication number: 20030185788
    Abstract: Transport reagents and conjugates of therapeutic agents linked to transport reagents are described. In particular, the transport reagents have a plurality of guanidinium moieties that are either contiguous or spaced along a backbone, but are sufficiently removed from the backbone via tethers, to allow their interaction with a cell or tissue surface, leading to uptake of the therapeutic agent.
    Type: Application
    Filed: December 11, 2002
    Publication date: October 2, 2003
    Inventors: Jonathan B. Rothbard, Paul A. Wender, Kanaka Pattabiraman, Erin T. Pelkey, Theodore C. Jessop
  • Bi-directional synthesis of oligoguanidine transport agents
    Publication number: 20030073807
    Abstract: Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of &ohgr;-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.
    Type: Application
    Filed: August 2, 2002
    Publication date: April 17, 2003
    Inventors: Paul A. Wender, Christopher L. VanDeusen, Kanaka Pattabiraman, Erin T. Pelkey, Theodore C. Jessop