Abstract: A novel method for quantifying a 25-hydroxyvitamin D concentration, a hydroxylase, a quantification composition, a quantification kit, an electrode, a sensor chip, and a sensor are provided. A method for quantifying 25-hydroxyvitamin D by adding a mediator and hydroxylase to a sample can be provided. Quantification of an oxidized mediator produced by an action of the hydroxylase, or oxygen or a reduced mediator consumed by an action of the hydroxylase may be included.

Abstract: A quantitation method of vitamin D derivative is provided including adding an oxidoreductase to a sample. The quantitation method of vitamin D derivative may further include reducing a mediator by adding the oxidoreductase, and reacting the reduced mediator with a reagent to determine a concentration of the vitamin D derivative.

Abstract: In one embodiment, an object of the present invention is to provide a firefly luciferase having improved thermostability. In one embodiment, the present invention relates to a luciferase mutant having improved thermostability that is a mutant of firefly luciferase comprising an amino acid sequence in which the amino acid residue at the position corresponding to position 393 of SEQ ID NO 1 is substituted, a polynucleotide encoding the luciferase mutant, and a production method of the luciferase mutant.

Abstract: In one embodiment, an object of the present invention is to provide a firefly luciferase having improved thermostability. In one embodiment, the present invention relates to a luciferase mutant having improved thermostability that is a mutant of firefly luciferase comprising an amino acid sequence in which the amino acid residue at the position corresponding to position 393 of SEQ ID NO 1 is substituted, a polynucleotide encoding the luciferase mutant, and a production method of the luciferase mutant.

Abstract: Niclosamide is an effective therapeutic medicament for the treatment of endometriosis. Niclosamide treatment can reduce the size of endometriotic lesions and reduce cell proliferation in the lesions. Niclosamide treatment can result in the inhibition of proteins and genes associated with inflammatory signaling, including those associated with NF?B and STAT3 activation, but without altering the expression of steroid hormone receptors. Niclosamide can be effective in reducing the growth of endometriotic lesions in female mice without impairing their ability to become pregnant and without negative effect on gestation and offspring. The invention herein is useful in treating symptoms associated with endometriosis, such as reducing the growth of lesions of the endometrium, without disrupting normal reproductive function in females. The invention also relates to derivatives of niclosamide having improved solubility and enhanced efficacy.

Abstract: A disposable hairbrush liner and a method of its use are disclosed. A disposable hairbrush liner for use with a hairbrush includes a non-woven cotton sheet and at least one substance applied to the sheet. The non-woven cotton sheet is comprised of cellulose and the substance is the extract from a natural plant.

Abstract: A heat-shrinkable laminated film having: (A) layer mainly having a polyester series resin; (C) layer mainly having a polystyrene series resin or mixture of polyester series and polystyrene series resins; and (B) layer mainly having polyester series and polystyrene series resins and disposed between (A) and (C) layers, the film having excellent heat-shrinkability, transparency, and interlayer-adhesiveness at room temperature, not easily peeled in a high-temperature treatment, inhibited from whitening when bent during processing, and suitable for shrinkage-packaging, shrink-bond-packaging, etc., with (B) layer having: a hard polyester series resin or mixture of hard polyester series and soft polyester series resins; and soft styrene series resin, hard styrene series resin, or mixture thereof, or with a content of the (B) layer polyester series resin smaller than that of the (A) layer one, and a content of the (C) layer polyester series resin smaller than that of the (B) layer one.

Abstract: A heat-shrinkable laminated film having: (A) layer mainly having a polyester series resin; (C) layer mainly having a polystyrene series resin or mixture of polyester series and polystyrene series resins; and (B) layer mainly having polyester series and polystyrene series resins and disposed between (A) and (C) layers, the film having excellent heat-shrinkability, transparency, and interlayer-adhesiveness at room temperature, not easily peeled in a high-temperature treatment, inhibited from whitening when bent during processing, and suitable for shrinkage-packaging, shrink-bond-packaging, etc., with (B) layer having: a hard polyester series resin or mixture of hard polyester series and soft polyester series resins; and soft styrene series resin, hard styrene series resin, or mixture thereof, or with a content of the (B) layer polyester series resin smaller than that of the (A) layer one, and a content of the (C) layer polyester series resin smaller than that of the (B) layer one.

Abstract: A scanner 1 reads image information at read resolution set by a resolution control section 3 and stores the image information in memory 2. An image separation section 11 separates the image information into a first image plane (picture part), a second image plane (text part color information), and a selection image plane (text part forms) for selecting either the first or second image plane. The resolution control section 3 sets optimum resolutions in first to third resolution conversion sections 12-14 in response to image quality, the original type, the system environment, the image plane characteristics, etc. The three image planes are converted into the resolutions set in the first to third resolution conversion sections 12-14. The image planes after undergoing the resolution conversion are compressed in first to third compression sections 15-17 and wrapped in one data format by an image format section 18.

Abstract: Input image information undergoes color conversion processing in a color conversion section 1, then is separated into first piece of image data, second piece of image data, and selection data in a multilayer data processing section 2 and transmission data in the multilayer data format is output. On the other hand, a 1-layer data processing section 3 prepares transmission data in the normal 1-layer data format from the image information. A color determination section 4 determines whether the input image information is a color or monochrome image. If the image information is determined a color image, a selection section 6 selects the transmission data in the multilayer data format; if the image information is determined a monochrome image, the selection section 6 selects the transmission data in the 1-layer data format. Then, it transmits the selected transmission data through a transmission section 7.