Abstract: The present invention relates to a pharmaceutical composition comprising an anti-PD-L1 antibody as an active ingredient, wherein the pharmaceutical composition is used in combination with camptothecin and/or a derivative thereof, or a pharmaceutically acceptable salt thereof.

Abstract: The present invention relates to a pharmaceutical composition comprising an anti-PD-L1 antibody as an active ingredient, wherein the pharmaceutical composition is used in combination with camptothecin and/or a derivative thereof, or a pharmaceutically acceptable salt thereof.

Abstract: A method for effectively suppressing GVHD, which occurs after peripheral blood stem cells allotransplantation, without causing marked side effects, and a pharmaceutical composition intended for this purpose and containing human G-CSF as an active ingredient. GVHD can be suppressed by administering human G-CSF to a transplantation recipient after peripheral blood stem cells transplantation.

Abstract: Disclosed is a method for stimulating revascularization in a subject comprising the steps of: (a) administering erythropoietin to the subject; (b) collecting peripheral blood mononuclear cells from the subject; and (c) administering the collected peripheral blood mononuclear cells to a target site of the subject. Peripheral blood mononuclear cells, and particularly CD34-positive cells, are mobilized into the peripheral blood of a subject by the administration of erythropoietin to the subject. The method of the present invention is useful for the treatment of ischemic diseases, such as peripheral vascular disorder.

Abstract: A duplex copier composed of a reading device which reads the image information written on the original document, which is set on the platen glass, a converting device for converting the image information read by the reading device to a digital signal, an image processor which processes the digital signal in predetermined manner, a copy machine having a duplex copy unit for making duplex copy, and an automatic document feeder which feeds the original document into the platen glass. The duplex copier is controlled to rotate the orientation of the image from that of the first side of the original by 90.degree. or 180.degree. when the image of the original is formed on the duplex copy sheet in various predetermined modes.

Abstract: A knotting method for a netting is disclosed which comprises the steps of seizing together a warp yarn which is paid out from a creel stand and a weft yarn which is paid out from a shuttle to form substantially concentric loops which are opposite in yarn feed direction to each other, pulling out the warp yarn upstream of the loop with respect to a feed direction of the warp yarn through the concentric loops to the opposite side, causing a weft supply side where the weft yarn is paid out to pass through a loop which is formed by the warp yarn as pulled out through the concentric loops, and tightening the warp and weft yarns which are intertwined. The resultant knot is firm and very small.

Abstract: A laminated bituminous roofing membrane including: (i) a fibrous sheet; (ii) a first bituminous layer laminated on one surface of the fibrous sheet, the bituminous layer being composed of bitumen or a bituminous mixture; (iii) a synthetic resin sheet or film laminated on the other surface, opposite to the surface laminated to the fibrous sheet, of the first bituminous layer; (iv) a second bituminous layer laminated on the other surface of the fibrous sheet, the bituminous layer being composed of bitumen or a bituminous mixture; and (v) a mineral aggregate layer deposited on the opposite surface of the second bituminous layer.This laminated bituminous roofing membrane can be readily and directly applied in a cold-application process on a substrate to form a waterproofing layer in which the joint portions of adjacent roofing membranes are completely water-tightly bonded and the formation of blistering and deterioration due to the presence of moisture or water from the substrate is prevented.

Abstract: A built-up bituminous waterproofing and thermal insulation assembly made by the process of placing onto a substrate a plurality of prefabricated, thermal insulating bituminous waterproofing boards adjacent to one another with the edges of the boards being slightly spaced to provide clearances therebetween, sealing the clearances with sealing material and then forming a continuous waterproofing layer over the entire upper surface of the boards and sealing material.

Abstract: A new thermal insulating and bituminous waterproofing board suitable for use in the combined application process of thermal insulation and built-up roofing or waterproofing, as well as the application process thereof are provided. This thermal insulating and bituminous waterproofing board contains: (i) a modified bitumen layer containing, as a principal constituent, a mixture of bitumen and at least one inorganic filler, which layer is formed in the form of a thick board; (ii) a flat sheet laminated on each surface of the modified bitumen layer, said flat sheet consisting of a fibrous sheet, and; (iii) a thermal insulating material layer bonded, via the flat sheets, to one surface of the modified bitumen layer. This thermal insulating and bituminous waterproofing board can be easily and reliably applied onto a substrate without any complex procedures and, also, without causing any damage to the thermal insulating material.

Abstract: An improved flashing sheet suitable for the formation of a flashing seal at a non-flat part having a three dimentional shape is provided. The flashing sheet comprises a base sheet of knitted fabrics having a high expandability in all directions and a modified bitumen layer of a mixture of bitumen and rubbers. This flashing sheet can be easily and directly applied onto the non-flat part of a substrate without any complex procedures and also without causing water leakage problems of the flashing seal.

Abstract: A novel self-adhesive type multi-layer laminated bituminous roofing membrane suitable for the formation of the roofing or waterproofing layer on roofs, floors and the like is provided. It comprises a base sheet of a sheet-like material, one or more bitumen layers coated on all or part of one or both faces of the base sheet, at least one layer of compound bitumen including both bitumen and rubber and/or resin laminated on all or part of the surface of said bitumen-coated layer on the base sheet and at least one release sheet laid over the whole surface of said compound bitumen layer.This roofing membrane is produced by uniting the bitumen-coated base sheet and the compound bitumen-coated release sheet, and can be applied over a substrate in a simple manner, without the step of melting or liquefying bitumen as in the conventional application process.

Abstract: A novel self-adhesive type multi-layer laminated bituminous roofing membrane suitable for the formation of the roofing or waterproofing layer on roofs, floors and the like is provided. It comprises a base sheet of a sheet-like material, one or more bitumen layers coated on all or part of one or both faces of the base sheet, at least one layer of compound bitumen including both bitumen and rubber and/or resin laminated on all or part of the surface of said bitumen-coated layer on the base sheet and at least one release sheet laid over the whole surface of said compound bitumen layer.This roofing membrane is produced by uniting the bitumen-coated base sheet and the compound bitumen-coated release sheet, and can be applied over a substrate in a simple manner, without the step of melting or liquefying bitumen as in the conventional application process.

Abstract: A novel combined application process of thermal insulation and built-up roofing or waterproofing is provided. In this application process, a foamed thermo-plastic thermal insulating material is bonded with a membrane having a tacky compound layer on one surface thereof so that the tacky compound layer is in close contact with the foamed thermoplastic material, without causing any damage due to heating, and a built-up roofing or waterproofing is formed on the other surface of the membrane according to the conventional application process.

Abstract: A novel self-adhesive type multi-layer laminated bituminous roofing membrane suitable for the formation of the roofing or waterproofing layer on roofs, floors and the like is provided. It comprises a base sheet of a sheet-like material, one or more bitumen layers coated on all or part of one or both faces of the base sheet, at least one layer of compound bitumen including both bitumen and rubber and/or resin laminated on all or part of the surface of said bitumen-coated layer on the base sheet and at least one release sheet laid over the whole surface of said compound bitumen layer.This roofing membrane is produced by uniting the bitumen-coated base sheet and the compound bitumen-coated release sheet, and can be applied over a substrate in a simple manner, without the step of melting or liquefying bitumen as in the conventional application process.

Abstract: A novel self-adhesive type multi-layer laminated bituminous roofing membrane suitable for the formation of the roofing or waterproofing layer on roofs, floors and the like is provided. It comprises a base sheet of a sheet-like material, one or more bitumen layers coated on all or part of one or both faces of the base sheet, at least one layer of compound bitumen including both bitumen and rubber and/or resin laminated on all or part of the surface of said bitumen-coated layer on the base sheet and at least one release sheet laid over the whole surface of said compound bitumen layer.This roofing membrane is produced by uniting the bitumen-coated base sheet and the compound bitumen-coated release sheet, and can be applied over a substrate in a simple manner, without the step of melting or liquefying bitumen as in the conventional application process.