Patents by Inventor Kanaya Lal Dhar

Kanaya Lal Dhar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 1,4 - dihydropyridines and novel 1,4-dihydropyridines useful as therapeutic agents
    Publication number: 20030230478
    Abstract: The present invention provides a process for the preparation of 1,4-dihydropyridines of the formula 1 1
    Type: Application
    Filed: March 20, 2003
    Publication date: December 18, 2003
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Neeraj Mahendroo, Ravi Kumar Khajuria, Kasturi Lal Bedi, Kanaya Lal Dhar, Vijay Kumar Kapoor
  • Process for preparing Topotecan from 10-hydroxy-4-(S) camptothecin
    Patent number: 6660861
    Abstract: The present invention relates to the use of dihalomethanes as reagents for the preparation of Topotecan{4-(S)-10(dimethylamino)-methyl-4-ethyl 4,9 dihydroxyl-H-pyrano[3′4′:6,7]indolizino-[1,2-b]quinoline-3,14(4H,12H)dione} from 10-hydroxycamptothecin. The invention discloses the rationale use of dichloromethane under solid-liquid phase transfer catalysis, which can behave both as solvent and a reactant when it serves as a source for C-1 unit for amino-alkylation of 10-hydroxy-4-(S)camptothecin.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: December 9, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Satish Chander Puri, Geeta Handa, Kanaya Lal Dhar, Om Parkash Suri, Ghulam Nabi Qazi
  • Trichosporon sp RRLY-15 (DSM 11829) and its use to prepare S(+)-6-methoxy-methyl-2-naphthalene acetic acid
    Patent number: 6242243
    Abstract: This invention discloses a process for the use of a novel organism belonging to the genus Trichosporon sp. as whole wet or dry cell culture or cell free extract or crude enzyme or pure isolated enzyme The strain of Trichosporon sp. used in the process is designated as RRLY-15 and has been deposited in Deutsche Sammlung von Mikroorganismen und Zellekulturen GmbH (DSMZ). The invention also discloses the preparation of S(+)-6-methoxy-2-naphthalene acetic acid (naproxen) of formula (2) through enantioselective hydrolysis of a racemic mixture of alkyl esters of (±)-6-methoxy-&agr;-methyl-2-naphthalene acetic acid of formula (1) where R represents —CH3,—C2H5,—C3H7,—C4H9 and the like and S(+)- Naproxen is a medicinally important non steroidal anti-inflammatory drug.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: June 5, 2001
    Assignee: Council of Scientific & Industrial Research
    Inventors: Ghulam Nabi Qazi, Rajinder Parshad, Surrinder Koul, Subhash Chandra Taneja, Kanaya Lal Dhar, Ravi Ji Kotru, Sukhdev Swami Handa