Patents by Inventor Kandikere R. Prabhu

Kandikere R. Prabhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bifunctional chelating agent for the design and development of site specific radiopharmaceuticals and biomolecule conjugation strategy
    Patent number: 6635235
    Abstract: There is provided a method of labeling a biomolecule with a transition metal or radiometal in a site specific manner to produce a diagnostic or therapeutic pharmaceutical compound by synthesizing a P2N2-bifunctional chelating agent intermediate, complexing the intermediate with a radio metal or a transition metal, and covalently linking the resulting metal-complexed bifunctional chelating agent with a biomolecule in a site specific manner. Also provided is a method of synthesizing the —PR2 containing biomolecules by synthesizing a P2N2-bifunctional chelating agent intermediate, complexing the intermediate with a radiometal or a transition metal, and covalently linking the resulting radio metal-complexed bifunctional chelating agent with a biomolecule in a site specific manner. There is provided a therapeutic or diagnostic agent comprising a —PR2 containing biomolecule.
    Type: Grant
    Filed: June 23, 2000
    Date of Patent: October 21, 2003
    Assignee: The Curators of the University of Missouri
    Inventors: Kattesh V. Katti, Kandikere R. Prabhu, Hariprasad Gali, Nagavara Kishore Pillarsetty, Wynn A. Volkert