Patents by Inventor Kang In Na

Kang In Na has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Humanized antibody specific for tumor necrosis factor-alpha
    Patent number: 7645450
    Abstract: Humanized antibodies specifically binding to hTNF-? are prepared from a mouse monoclonal antibody by the CDR (complementarity determining region) grafting method, and they show an antigen binding affinity similar to the original mouse monoclonal antibody and significantly low immunogenicity. Therefore, the humanized antibodies can be effectively used for treating a hTNF-?-related disease such as rheumatoid arthritis, Crohn's disease, psoriatic arthritis, psoriasis, septicemia, asthma, Wegener's granulomatosis, inflammation, and ankylosing spondylitis.
    Type: Grant
    Filed: December 29, 2005
    Date of Patent: January 12, 2010
    Assignee: Yuhan Corporation
    Inventors: Tae Hyoung Yoo, Moo Young Song, Chang Seok Kim, Sang Koo Park, Kang In Na, Byung Kyu Lee, Heui Il Kang
  • Humanized antibody against S-surface antigen of hepatitis B virus
    Patent number: 7435414
    Abstract: A humanized antibody of the present invention shows similar antigen-binding affinity to a mouse monoclonal antibody and significantly low immunogenecity. Therefore, the humanized antibody of the present invention can be effectively used for treating chronic hepatitis B and preventing HBV infection of a patient received liver transplantation and vertical transmission from a mother infected with HBV to a fetus.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: October 14, 2008
    Assignee: Yuhan Corporation
    Inventors: Heui Il Kang, Byung Kyu Lee, Se Cheol Park, Moo Young Song, Tae Hyoung Yoo, Jae Sun Lee, Chang Seok Kim, Sang Koo Park, Kang In Na
  • Humanized Antibody Specific For Tumor Necrosis Factor-Alpha
    Publication number: 20080008703
    Abstract: Humanized antibodies specifically binding to hTNF-? are prepared from a mouse monoclonal antibody by the CDR (complementarity determining region) grafting method, and they show an antigen binding affinity similar to the original mouse monoclonal antibody and significantly low immunogenicity. Therefore, the humanized antibodies can be effectively used for treating a hTNF-?-related disease such as rheumatoid arthritis, Crohn's disease, psoriatic arthritis, psoriasis, septicemia, asthma, Wegener's granulomatosis, inflammation, and ankylosing spondylitis.
    Type: Application
    Filed: December 29, 2005
    Publication date: January 10, 2008
    Inventors: Tae Hyoung Yoo, Moo Young Song, Chang Seok Kim, Sang Koo Park, Kang In Na, Byung Kyu Lee, Heui Il Kang
  • Antibody variable region of a monoclonal antibody against human tumor necrosis factor alpha and a gene encoding the same
    Patent number: 7196177
    Abstract: An antibody variable region of a monoclonal antibody specifically binding to human tumor necrosis factor-? contains at least one of a heavy chain variable region and a light chain variable region having specific complementarity determining regions therein. A nucleic acid molecule encoding the same, a recombinant vector containing the nucleic acid molecule, and a cell transformed with the recombinant vector are also provided.
    Type: Grant
    Filed: March 16, 2006
    Date of Patent: March 27, 2007
    Assignee: Yuhan Corporation
    Inventors: Heui II Kang, In Young Ko, Moo Young Song, Chang Seok Kim, Sang Koo Park, Jae Sun Lee, Tae Hyoung Yoo, Kang In Na
  • Nucleic acid molecules encoding human tumor necrosis factor ?-specific antibodies
    Patent number: 7109320
    Abstract: An antibody variable region of a monoclonal antibody specifically binding to human tumor necrosis factor-? contains at least one of a heavy chain variable region and a light chain variable region having specific complementarity determining regions therein. A nucleic acid molecule encoding the same, a recombinant vector containing the nucleic acid molecule, and a cell transformed with the recombinant vector are also provided.
    Type: Grant
    Filed: November 16, 2004
    Date of Patent: September 19, 2006
    Assignee: Yuhan Corporation
    Inventors: Heui Il Kang, In Young Ko, Moo Young Song, Chang Seok Kim, Sang Koo Park, Jae Sun Lee, Tae Hyoung Yoo, Kang In Na