Patents by Inventor Kang-Ping Lin
Kang-Ping Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11920157Abstract: Applications of butylidenephthalide (BP), comprising the use of BP in providing a kit for promoting differentiation of stem cells into brown adipose cells, and the use of BP in preparing a medicament, wherein the medicament is used for inhibiting the accumulation of white adipose cells, promoting the conversion of white adipose cells into brown adipose cells, inhibiting weight gain and/or reducing the content of triglycerides, glucose, and total cholesterol in blood.Type: GrantFiled: September 15, 2022Date of Patent: March 5, 2024Assignee: NATIONAL DONG HWA UNIVERSITYInventors: Tzyy-Wen Chiou, Shinn-Zong Lin, Horng-Jyh Harn, Hong-Lin Su, Shih-Ping Liu, Kang-Yun Lu, Jeanne Hsieh
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Publication number: 20220133188Abstract: A topical subcutaneous microcirculation detection device includes a first light source module, a second light source module, a lens plate, a first light sensor, and a second light sensor. The first and second light source modules are configured to emit first and second illumination beams, respectively. A flat plate portion of the lens plate is disposed to lean against a first portion of skin of a subject. A convex surface of a first convex lens portion of the lens plate is disposed to push into a second portion of the skin of the subject. The first and second illumination beams are reflected into first and second reflected beams by the first and second portions of the skin, respectively. The first and second reflected beams are transmitted to the first and second light sensors, respectively.Type: ApplicationFiled: October 15, 2021Publication date: May 5, 2022Applicant: Chung Yuan Christian UniversityInventors: Kang-Ping Lin, Cheng Lun Tsai, Shao-Hung Lu, Mei-Fen Chen
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Patent number: 11094065Abstract: A method and a system are provided for automatically delineating a striatum in a nuclear medicine brain image and calculating a striatum specific uptake ratio. In the method, initially, a target image is obtained. Then, the target image is projected to a space coordinate to generate a projection amount; an upper end and a lower end of a brain are obtained; and a preset range from the upper to the lower ends is set as a striatum slice area in the target image. A brain area is determined from the target image by a line detection method. Then, a brain volume template is deformed according to the brain area and the striatum slice area, so that a striatum in the brain volume template corresponds to the target image to delineate a striatum region of the target image. Finally, a specific uptake ratio of the striatum region can be calculated.Type: GrantFiled: April 5, 2020Date of Patent: August 17, 2021Assignee: Chung Yuan Christian UniversityInventors: Wen-Chen Lin, Kang-Ping Lin
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Publication number: 20210110544Abstract: A method and a system are provided for automatically delineating a striatum in a nuclear medicine brain image and calculating a striatum specific uptake ratio. In the method, initially, a target image is obtained. Then, the target image is projected to a space coordinate to generate a projection amount; an upper end and a lower end of a brain are obtained; and a preset range from the upper to the lower ends is set as a striatum slice area in the target image. A brain area is determined from the target image by a line detection method. Then, a brain volume template is deformed according to the brain area and the striatum slice area, so that a striatum in the brain volume template corresponds to the target image to delineate a striatum region of the target image. Finally, a specific uptake ratio of the striatum region can be calculated.Type: ApplicationFiled: April 5, 2020Publication date: April 15, 2021Applicant: Chung Yuan Christian UniversityInventors: Wen-Chen Lin, Kang-Ping Lin
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Publication number: 20160151037Abstract: A stethoscope device is disclosed, which comprises a heart sound sensor comprising a sensing portion to detect a heart sound signal having a periodic first heart sound and a periodic second heart sound; an electrocardiogram sensor comprising two electrodes to detect an electrocardiogram signal having a periodic R wave; a microprocessor for extracting amplitudes of the R wave from the electrocardiogram signal and analyzing appearing positions of the R wave to provide appearing positions of a periodic notification pulse wave to a predetermined reference signal and combine the reference signal with the heart sound signal to form a sound signal; and an output unit to output the sound signal; wherein each pulse of the notification pulse wave of the sound signal provides a notification sound.Type: ApplicationFiled: November 27, 2015Publication date: June 2, 2016Inventors: Kang-Ping LIN, Bor-Iuan JAN, Hao-Yu CHAN, Keng-Hung LIN, Yu-Hong YAN, Sheng-Kai YANG
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Publication number: 20160081631Abstract: A respiratory waveform recognition method comprises: (a) detecting a respiratory airflow in a respiratory cycle; (b) measuring an amplitude of the respiratory airflow and a duration of the respiratory cycle; (c) using a plurality of sampling points to determine an inspiration waveform and an expiration waveform according to the amplitude and the duration; (d) normalizing the amplitude and the duration of one of the inspiration waveform and the expiration waveform, so as to establish a normalized waveform; and (e) accumulating the differences between the normalized waveform and a reference waveform to calculate a flow index useful for the identification of a normal respiration state and an abnormal respiration state. A curve, such as a weighted curve or a standard waveform, is used for fitting of the inspiration waveform or the expiration waveform to calculate the differences, and the differences are accumulated to identify the normal respiration state and the abnormal respiration state.Type: ApplicationFiled: September 23, 2014Publication date: March 24, 2016Inventors: Kang-Ping LIN, Geng-Hong LIN, Hao-Yu JAN, Sheng-Cheng HUANG, Po-Chung SHIN, Ching-Liang YU, Da-Long LEE
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Publication number: 20140055557Abstract: An automated external defibrillator (AED) with a panoramic video camera device comprises a case, an AED accommodated by the case, a microprocessor built in the AED, an image capture device electrically connected with the microprocessor, a memory electrically connected with the microprocessor and storing the images captured by the image capture device, and a panoramic lens arranged above the image capture device. During usage, the present invention takes motion pictures panoramically to provide more detailed information for the medical personnel after the patient has been transported to the hospital and ascertain the truth for a medical dispute.Type: ApplicationFiled: March 14, 2013Publication date: February 27, 2014Applicant: CHUNG YUAN CHRISTIAN UNIVERSITYInventors: Cheng-Lun TSAI, Kang-Ping LIN, Hen-Hong CHANG, Chi-Ping TAI, Wen-Chih LIN
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Publication number: 20130138196Abstract: An electrode pad set comprises a left electrode pad, a right electrode pad, a first indication figure on the left electrode pad, a second indication figure on the right electrode pad. The left electrode pad and the right electrode pad respectively have a first warning sign with a first shape and a second warning sign with a second shape corresponding to the first shape. The perimeter of the first warning sign has a first coating with a first color. The perimeter of the second warning sign has a second coating with a second color. A left electrode pad symbol of the first indication figure has a color identical to the first color. A right electrode pad symbol of the second indication figure has a color identical to the second color. The present invention uses colors, shapes and indication figures to promote the success rate of attaching the electrode pads.Type: ApplicationFiled: November 29, 2011Publication date: May 30, 2013Inventors: Cheng-Lun TSAI, Kang Ping Lin, Yi-Rou Lin, Yu-Ju Chiang, Shih-Wei Liu
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Publication number: 20130046191Abstract: The present invention discloses a system and method to measure the pulse pressure signals, which inflates and deflates at least one air bag to detect pulse pressure signals of a human limb. The system comprises a detection device and a host device. The detection device is place on an artery of a human limb and includes one or more air bags. The host device controls inflation and deflation of the air bags, measures pressure variation of the air bags, and records and analyzes pulse pressure signals. The system and method of the present invention can simulate the three-finger technique of pulse diagnostics of the traditional Chinese medicine and provide physicians with more reliable pulse-diagnostics information.Type: ApplicationFiled: November 29, 2011Publication date: February 21, 2013Inventors: Kang Ping Lin, Hen Hong Chang, Wen Chen Lin, Geng Hong Lin
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Publication number: 20130046192Abstract: An image-based PWV measurement device and method are provided. The measurement device comprises at least two light emitting units respectively projecting light beams to at least two detected regions on body surface; at least two light transmitting units respectively receiving and transmitting light signals measured at the different detected regions; an image sensing unit converting the light signals measured at the detected regions into image signals; a length measurement unit used to measure the distance between the detected regions; and an image analysis unit analyzing the image signals to obtain PPG signals for the detected regions. According to the PPG signals, the image analysis unit calculates the physiological parameters, including the perfusion index, respiration rate, pulse rate, stiffness index, reflection index, and PWV between the detected regions, which is derived according to the distance and the pulse transit time from the PPG signals of the two detected regions.Type: ApplicationFiled: November 30, 2011Publication date: February 21, 2013Inventors: Yue-Der LIN, Ching Che TSAI, Hu Ying HO, Shih Fan WANG, Kang Ping LIN, Hen Hong CHANG, Yung Ching CHANG
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Publication number: 20130046154Abstract: The present invention discloses a PPG imaging device and a PPG measuring method. The PPG imaging device comprises a light emitting unit, a collimator unit, a beam splitter unit, an image sensing unit, and an image analysis unit. The light emitting unit provides an incident light signal. The collimator unit receives the incident light signal and transforms the incident light signal into a parallel light signal. The beam splitter unit receives the parallel light signal and reflects it to a tested region. The image sensing unit receives a reflected light signal reflected from the tested region and converts it into image signals. The image analysis unit connects with the image sensing unit and analyzes the image signals to obtain PPG signals of the tested region. The PPG imaging device may be arranged in an anti-light pollution unit, whereby to prevent from optical interference and obtain higher measurement precision.Type: ApplicationFiled: November 29, 2011Publication date: February 21, 2013Inventors: Yue Der Lin, Shih Fan Wang, Hu Ying Ho, Ching Che Tsai, Kang Ping Lin, Hen Hong Chang, Yung Ching Chang
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Patent number: 7504082Abstract: Magnetic nanoparticles are applicable in imaging, diagnosis, therapy, and biomaterial separation. The magnetic nanoparticles are represented as (FewGdx)vZy, wherein w is from 99.9% to 97.5%, x is from 0.1% to 2.5%, Z is an element of the group VIa, and v, y are positive numbers.Type: GrantFiled: January 20, 2006Date of Patent: March 17, 2009Assignee: Industrial Technology Research instituteInventors: Hui-Ju Cho, Sheng-Ming Shih, Yuh-Jiuan Lin, Hong-Dun Lin, Kang-Ping Lin
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Patent number: 7471976Abstract: A device for measuring an electrocardiogram with a tapeless format and its method is provided with electrodes having a flat shape that are contacted by root portions between two fingers of a user's hands or by two fingers of each of the user's hands. The electrocardiogram can be measured directly by that contact, without adding any conductive liquid or gel material.Type: GrantFiled: January 9, 2004Date of Patent: December 30, 2008Inventors: Kang-Ping Lin, Chih-Hui Hsieh
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Publication number: 20080241963Abstract: A biochemical labeling material and manufacturing method thereof. The manufacturing method provides a plurality of nanoparticles, bonding the nanoparticles to template molecules by molecular imprinting, polymerizing the nanoparticles to form a matrix with uniformly-distributed template molecules, finally removing the template molecules from the matrix to reveal a detection group of the matrix, leaving a cavity with specific area.Type: ApplicationFiled: December 31, 2007Publication date: October 2, 2008Inventors: Chin-I Lin, Kang-Ping Lin, Yuh-Jiuan Lin, Sheng-Ming Shih, Abraham Joseph K, Chao-Kang Chang
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Patent number: 7396589Abstract: Magnetic nanoparticles are applicable in imaging, diagnosis, therapy, and biomaterial separation. The magnetic nanoparticles comprise a core represented as FexMavZy and a shell of an inner-transition element Mb or the compound thereof, wherein Ma is an inner-transition element, Z is an element of the group Vla, x is greater or equal to 0, and v, y are positive numbers. The surface of the shell is optionally modified by liposome, polymer, aliphatic compound, aromatic compound or combinations thereof.Type: GrantFiled: March 19, 2007Date of Patent: July 8, 2008Assignee: Industrial Technology Research InstituteInventors: Hui-Ju Cho, Sheng-Ming Shih, Yuh-Jiuan Achuan Lin, Hong-Dun Lin, Kang-Ping Lin
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Patent number: 7338812Abstract: A biochemical labeling material and manufacturing method thereof. The manufacturing method provides a plurality of nanoparticles, bonding the nanoparticles to template molecules by molecular imprinting, polymerizing the nanoparticles to form a matrix with uniformly-distributed template molecules, finally removing the template molecules from the matrix to reveal a detection group of the matrix, leaving a cavity with specific area.Type: GrantFiled: June 23, 2003Date of Patent: March 4, 2008Assignee: Industrial Technology Research InstituteInventors: Chin-I Lin, Kang-Ping Lin, Yuh-Jiuan Lin, Sheng-Ming Shih, K Abraham Joseph, Chao-Kang Chang
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Patent number: 7270636Abstract: An apparatus and method for pulse detection based on blood pressure measuring stage is disclosed. Both monitoring of blood pressure and blood vessel pulse are integrated and applied to an apparatus. With the components of the blood pressure monitor, such as an inflatable cuff an air pump and a variable flow valve, with a unique sequential pressure control of reduction and regulation of pressure, not only can blood pressure parameters but also pulse signals under various pressures be measured to provide a complete analysis of blood artery/vessel conditions.Type: GrantFiled: November 2, 2005Date of Patent: September 18, 2007Assignee: DailyCare BioMedical Inc.Inventors: Kang-Ping Lin, Hong-Dun Lin, Bor-Iuan Jan, Mei-Feng Chen
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Publication number: 20070166232Abstract: Magnetic nanoparticles are applicable in imaging, diagnosis, therapy, and biomaterial separation. The magnetic nanoparticles comprise a core represented as FexMavZy and a shell of an inner-transition element Mb or the compound thereof, wherein Ma is an inner-transition element, Z is an element of the group Vla, x is greater or equal to 0, and v, y are positive numbers. The surface of the shell is optionally modified by liposome, polymer, aliphatic compound, aromatic compound or combinations thereof.Type: ApplicationFiled: March 19, 2007Publication date: July 19, 2007Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Hui-Ju Cho, Sheng-Ming Shih, Yuh-Jiuan Lin, Hong-Dun Lin, Kang-Ping Lin
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Publication number: 20070038135Abstract: A portable bio parameter detection/display assembly includes an optical sensor for engagement with an operator to acquire a pulse signal, an A/D converter converting the pulse signal into a digital format, a microprocessor for receiving the digital format pulse signal and proceeding with calculation of a pulse rate and at least one heart rate variability parameter, a display to display and a power module to provide necessary electricity to the assembly.Type: ApplicationFiled: May 22, 2006Publication date: February 15, 2007Inventors: Kang-Ping Lin, Bor-Iuan Jan, Hao-Yu Jan, Geng-Hong Lin
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Publication number: 20060287605Abstract: The invention discloses an heart rate variability (HRV) analyzing device, which integrates the ECG signal measuring and processing technology and combines the HRV analyzing functions. The device adopts sensing electrodes disposed thereon or external sensing electrodes to record a subject's ECG signals. After being amplified, filtered and analog-to-digital converted, the ECG signals are transmitted to a built-in CPU to proceed with time domain and frequency domain analysis, and the results of the analysis are shown on a display unit. In such a way, the signal acquisition, algorithm calculation and display can be completed in the single device of the invention, which simplifies the conventional instruments and equipment, and provides an indication of the subject's health state in the aspect of self-health care.Type: ApplicationFiled: June 16, 2005Publication date: December 21, 2006Applicant: DAILYCARE BIOMEDICAL INC.Inventors: Kang-Ping Lin, Geng-Hong Lin, Bor-Iuan Jan