Abstract: A ductile material, a method for manufacturing a ductile member, and an anti-collision device for bridge piers, wherein the ductile material includes specific components in parts by mass as follows: 50-62 parts of thermoplastic polyurethane, 11-33 parts of neodymium-iron-boron, 12-24 parts of nickel-titanium alloy, 2-3 parts of metal magnetic powder, and 1-2 parts of polypropylene or polyethylene or polylactic acid or polyetheretherketone. The use of the ductile material, the method for manufacturing a ductile member, and the anti-collision device for bridge piers facilitates navigation.

Abstract: Provided are antibodies that specifically bind to TIGIT (T cell immunoreceptor with Ig and ITIM domains, WUCAM or Vstm3) and inhibit Tigit-mediated cellular signaling and activities in immune cells. The anti-TIGIT antibodies can be used to treat or diagnose cancer, infectious diseases or other pathological disorders that may be modulated by Tigit-mediated functions.

Abstract: A method and a device for determining a radiation delivery plan, a computer equipment, a storage medium and a computer program product. The method includes: obtaining an image of a target object, and determining a predicted dose distribution of the target object according to the image of the target object; and determining an objective dose distribution for the radiation delivery plan based on the predicted dose distribution and a plan-quality control strategy.

Abstract: Provided are antibodies that specifically bind to Programmed Death-1 (PD1, Pdcd-1, or CD279) and inhibit PD1-mediated cellular signaling and activities in immune cells, antibodies binding to a set of amino acid residues required for its ligand binding, and uses of these antibodies to treat or diagnose cancer, infectious diseases or other pathological disorders modulated by PD1-mediated functions.

Abstract: A fan with increased heat-removing ability and reduced noise in operation includes a hub, a baffle, a first blade layer, and a second blade layer. The first blade layer includes a plurality of first blades, and the second blade layer includes a plurality of second blades. An orthogonal projection of each of the plurality of first blades on the baffle is located between orthogonal projections of adjacent two of the plurality of second blades on the baffle. A length of the plurality of first blades is greater or less than a length of the plurality of second blades to avoid any resonance. An electronic device including the fan is also disclosed.

Abstract: An LED light-emitting module is provided, including a glass substrate, a drive circuit, an LED light-emitting assembly, and a drive chip. The drive circuit is disposed on a side surface of the glass substrate. The LED light-emitting assembly includes a plurality of LED light sources arranged in an array manner. The LED light-emitting assembly is disposed on a surface of the drive circuit and is electrically connected to the drive circuit. The drive chip is connected to the drive circuit, and controls, by using the drive circuit, the LED light source in the LED light-emitting assembly to be turned on or off.

Abstract: A display panel and a display apparatus are described. In an embodiment, the display panel includes a display area and a bezel area; a first support structure located in the display area, the first support structure including a plurality of first support portions; an encapsulation adhesive located in the bezel area; a second support structure located in the bezel area. In an embodiment, at different positions of the bezel area, the second support structure and the encapsulation adhesive are at an equal distance from each other within a preset error range; the second support structure includes at least one second support portion; and in a direction perpendicular to a plane in which the display panel is located, at least some of the second support portions each has orthographic projection area larger than orthographic projection area of the first support portion.

Abstract: A display panel has functional component regions arranged along a first direction and a display region at least partially surrounding the functional component regions. The display panel includes first signal lines located in the display region. One of the first signal lines has a least one part extending in the first direction, and the first signal lines are arranged in a second direction intersecting with the first direction. The first signal lines include a first-type signal line and a second-type signal line, and the first-type signal line at least partially surrounds the functional component regions. In the first direction, at least one second-type signal line is broken at two sides of one of the functional component region.

Abstract: Disclosed is a method for increasing expression level of recombinant proteins in Bacillus subtilis through co-expressing Bacillus-derived enhancer factor, belonging to the technical field of enzyme engineering. According to the present disclosure, genes encoding recombinant proteins are respectively co-expressed with Bacillus-derived PonA, PonA truncated forms, OppA or SppA, so as to improve the expression level of the recombinant proteins. The results show that the method provided by the present disclosure can increase the expression level of ultra-high temperature amylase, medium temperature amylase or sucrose isomerase at the shake flask level to 3.96 times, 1.49 times and 2.26 times. The expression level of ultra-high temperature amylase can be increased by 26% in high-density fermentation of a 3L bioreactor. The B. subtilis provides a new developable target as an recombinant protein expression host, and provides technical support for the optimization and modification of the enhancer factors.

Abstract: An intelligent separation method of peanut kernel and red coat, feeding peanuts to be removed red coats into a device for a gas explosion of the red coats of the peanuts, to complete a preliminary separation of kernels and the red coats of the peanuts; feeding the primarily separated kernels and peanut red coats of the peanuts into the drying device to fully separate the red coats from the kernels; delivering the fully separated peanut kernels and red coats of the peanuts into a negative pressure adsorption device to collect respectively the fully separated kernels and red coats of the peanuts with different densities and qualities by a negative pressure adsorption mode, finally obtaining the kernels of the peanuts without the red coats, and the red coats of the peanuts respectively.

Abstract: A display device includes: a display panel; and a polarizer, an optical adhesive, and a cover plate sequentially arranged on the display panel. The display panel has a transparent region. The polarizer has first and second surfaces parallel to each other, and the first surface is proximal to the display panel. The polarizer has therein a through hole penetrating through the first and second surfaces. The through hole has first and second boundaries at the first and second surfaces, respectively. An orthogonal projection of the first boundary on the second surface is inside and not in contact with the second boundary. For third and fourth boundaries of the through hole parallel to the first boundary, an orthogonal projection of the third boundary on the fourth boundary does not extend beyond the fourth boundary, the third boundary being closer to the first boundary than the fourth boundary.

Abstract: Provided are a display substrate, a method for manufacturing a display substrate and a display apparatus. The display substrate includes a base, a drive structure layer disposed on the base, a light emitting element disposed on the drive structure layer, an encapsulation layer disposed on the light emitting element, a circular polarizer layer disposed on the encapsulation layer, and a lens definition layer and a lens structure layer disposed on the circular polarizer layer. The light emitting element includes a pixel definition layer provided with a plurality of sub-pixel openings; the lens structure layer includes a plurality of lenses disposed at intervals, the lens definition layer is disposed in a gap region between adjacent lenses, and an orthographic projection of each lens on the base contains an orthographic projection of a sub-pixel opening on the base.

Abstract: A secure ranging method and an apparatus are provided. The method includes: a receiving-end device and a transmitting-end device obtain a session key through a narrowband system. The devices of both parties further generate secure CTSs in a symmetric manner based on the session key in combination with CTS configuration information, and perform inter-device ranging in a UWB system by using the CTSs. According to this application, the CTS can be flexibly configured based on the CTS configuration information, to improve secure ranging performance. In addition, the narrowband system replaces the UWB system to perform key-related information negotiation, and ranging is performed in the UWB system, so that high-accuracy ranging is implemented while low power consumption is considered.

Abstract: This application discloses a method for updating a virtual environment picture performed by a computer device. The method includes: displaying a first virtual environment picture of a virtual environment using a first observation position as an observation center, wherein a virtual character is located at a first position in the first virtual environment picture; in response to receiving a first directional operation on the virtual character, displaying a skill indicator in accordance with the first directional operation; and when at least a portion of the skill indicator is going to exceed the first virtual environment picture, replacing the first virtual environment picture with displaying a second virtual environment picture, wherein the virtual character is relocated from the first position in the first virtual environment picture to a second position in the second virtual environment picture so as to present the skill indicator in the second virtual environment picture.

Abstract: A smart device for reducing sound leakage includes a frame, a main sound-generating device, an auxiliary sound-generating device, and a controller. The controller is configured to generate a control signal based on an electrical signal of the main sound-generating device to trigger the auxiliary sound-generating device to generate sound, so that the sound generated by the auxiliary sound-generating device and sound generated by the main sound-generating device through the sound outlet hole are superposed on each other, or the sound generated by the auxiliary sound-generating device and sound leakage generated by the main sound-generating device through the sound leakage hole form a dipole effect and counteract each other. The smart device according to the present disclosure can further reduce the sound leakage to improve privacy of the smart device for reducing sound leakage, which can also achieve an effect of improving sound quality.

Abstract: This application discloses a method for operating virtual characters within a virtual environment performed by a computer device.

Abstract: Describes are shutter disks comprising one or more of titanium (Ti), barium (Ba), or cerium (Ce) for physical vapor deposition (PVD) that allows pasting to minimize outgassing and control defects during etching of a substrate. The shutter disks incorporate getter materials that are highly selective to reactive gas molecules, including O2, CO, CO2, and water.

Abstract: The present disclosure describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. Compounds of the disclosure have activity as dual modulators of Janus kinase (JAK), alone, or in combination with one or more of an additional mechanism, including a tyrosine kinase, such as TrkA or Syk, and PDE4, and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described herein are methods of treating inflammation, auto-immune diseases, cancer, and other conditions susceptible to inhibition of JAK and PDE4 by administering a compound herein described.

Abstract: Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.

Abstract: The present application relates to a method and an apparatus for training machine learning models, a computer device, and a storage medium. The method includes: acquiring a first training sample set and a second training sample set; performing, based on the first training sample set, multiple rounds of model training, to obtain a first machine learning model; and performing, based on the second training sample set, multiple rounds of model training, to obtain a second machine learning model. At least a part of the first machine learning model has a same structure as at least a part of the second machine learning model, at least a part of model parameters of the second machine learning model is used when the first machine learning model is trained, and at least a part of model parameters of the first machine learning model is used when the second machine learning model is trained.