Abstract: Disclosed herein are systems, methods, devices, and media for carrying out detection of ophthalmic and systemic diseases and disorders. Deep learning algorithms enable the automated analysis of ophthalmic images such as retinal scans to generate accurate detection of various diseases and disorders. Point-of-care implementations allow for rapid and efficient detection outside of the clinical setting.

Abstract: Provided are a computer program product, system, and method for verifying translations of text in a source language to target text in a target language. A source similarity score is calculated indicating a similarity between a first text and second text in a source language. A target similarity score is calculated between translated first text, comprising a translation of the first text in a target language, and translated second text, comprising a translation of the second text in the target language. A determination is made whether the translation of the first text to the translated first text is of an inappropriate translation quality based on the source similarity score and the target similarity score. Indication is made of indicating the inappropriate translation quality in response to determining the inappropriate translation quality.

Abstract: A virtual object control method includes: controlling a first virtual object to move toward a target position in response to detecting a triggering operation on a first skill; while the first skill is in effect, detecting a triggering operation on a second skill; in response to detecting the triggering operation on the second skill: searching, based on the target position, for a target virtual object; and in accordance with a determination that the first virtual object reaches the target position: controlling the first virtual object to cast the second skill on the target virtual object. Searching is performed based on the target position associated with the first skill, so that a target actually attacked matches a target the user intends to attack, thereby improving the efficiency of human-machine interaction.

Abstract: Disclosed herein are methods, probes, and kits for diagnosing the presence of cancer and/or a cancer type in a subject.

Abstract: Provided is an adaptive strap for brassieres having at least one adaptive material layer (10) having a first strength modulus x during static loading and a second strength modulus of at least 2× during dynamic loading of at least approximately 3 Hz oscillation. The adaptive layer (10) is sandwiched between two or more elastic fabric layers (20). The adaptive strap is extendable up to 100% of its initial length during low wearer activity but is extendable not more than 50% during vigorous wearer activity, providing support during exercise and comfort during daily use. In one aspect the adaptive material is a reaction product formed by reacting a silanol terminated polydimethylsiloxane, polymer matrix, boric acid and optional fillers. The adaptive material (10) is cured in situ within the elastic fabric layers (20).

Abstract: A circuit board with anti-corrosion properties, a method for manufacturing the circuit board, and an electronic device are provided. The circuit board includes a circuit substrate, a first protective layer, and a second protective layer. The circuit substrate includes a base layer and an outer wiring layer formed on the base layer. The circuit substrate further defines a via hole connected to the outer wiring layer. The first protective layer is formed on the outer wiring layer and an inner sidewall of the via hole, and is made of a white oil. The second protective layer is formed on the first protective layer.

Abstract: Disclosed herein are therapeutic agents capable of increasing the expression level of an epigenetic marker described herein. Also described herein are therapeutic agents that reduce or slow-down an aging phenotype.

Abstract: A system may include a memory and a processor in communication with the memory. The processor may be configured to perform operations. The operations may include calculating a priority factor with a node autonomous center in a node and computing a node service capability with the node autonomous center. The operations may further include selecting, with the node autonomous center, a task based on the priority factor and the node service capability. The operations may further include directing the task to the node.

Abstract: Disclosed herein, in certain embodiments, are methods and kits for diagnosing a subject as having hepatocellular carcinoma (HCC) or lung cancer. In some instances, also described herein are methods of determining the prognosis of the subject having HCC or lung cancer. In additional instances, described herein are methods of determining the specific staging of HCC or lung cancer in a subject.

Abstract: An energy dissipating fiber and fabric for protective textile application, which can absorb energy during shocking, stretching and vibration. The disclosed fiber/fabric can include a polymer matrix, a shear-thickening material and a reinforcing filler.

Abstract: A method and a device for determining a radiation delivery plan, a computer equipment, a storage medium and a computer program product. The method includes: obtaining an image of a target object, and determining a predicted dose distribution of the target object according to the image of the target object; and determining an objective dose distribution for the radiation delivery plan based on the predicted dose distribution and a plan-quality control strategy.

Abstract: A fan with increased heat-removing ability and reduced noise in operation includes a hub, a baffle, a first blade layer, and a second blade layer. The first blade layer includes a plurality of first blades, and the second blade layer includes a plurality of second blades. An orthogonal projection of each of the plurality of first blades on the baffle is located between orthogonal projections of adjacent two of the plurality of second blades on the baffle. A length of the plurality of first blades is greater or less than a length of the plurality of second blades to avoid any resonance. An electronic device including the fan is also disclosed.

Abstract: Disclosed is a method for increasing expression level of recombinant proteins in Bacillus subtilis through co-expressing Bacillus-derived enhancer factor, belonging to the technical field of enzyme engineering. According to the present disclosure, genes encoding recombinant proteins are respectively co-expressed with Bacillus-derived PonA, PonA truncated forms, OppA or SppA, so as to improve the expression level of the recombinant proteins. The results show that the method provided by the present disclosure can increase the expression level of ultra-high temperature amylase, medium temperature amylase or sucrose isomerase at the shake flask level to 3.96 times, 1.49 times and 2.26 times. The expression level of ultra-high temperature amylase can be increased by 26% in high-density fermentation of a 3L bioreactor. The B. subtilis provides a new developable target as an recombinant protein expression host, and provides technical support for the optimization and modification of the enhancer factors.

Abstract: This application discloses a method for updating a virtual environment picture performed by a computer device. The method includes: displaying a first virtual environment picture of a virtual environment using a first observation position as an observation center, wherein a virtual character is located at a first position in the first virtual environment picture; in response to receiving a first directional operation on the virtual character, displaying a skill indicator in accordance with the first directional operation; and when at least a portion of the skill indicator is going to exceed the first virtual environment picture, replacing the first virtual environment picture with displaying a second virtual environment picture, wherein the virtual character is relocated from the first position in the first virtual environment picture to a second position in the second virtual environment picture so as to present the skill indicator in the second virtual environment picture.

Abstract: A smart device for reducing sound leakage includes a frame, a main sound-generating device, an auxiliary sound-generating device, and a controller. The controller is configured to generate a control signal based on an electrical signal of the main sound-generating device to trigger the auxiliary sound-generating device to generate sound, so that the sound generated by the auxiliary sound-generating device and sound generated by the main sound-generating device through the sound outlet hole are superposed on each other, or the sound generated by the auxiliary sound-generating device and sound leakage generated by the main sound-generating device through the sound leakage hole form a dipole effect and counteract each other. The smart device according to the present disclosure can further reduce the sound leakage to improve privacy of the smart device for reducing sound leakage, which can also achieve an effect of improving sound quality.

Abstract: This application discloses a method for operating virtual characters within a virtual environment performed by a computer device.

Abstract: Describes are shutter disks comprising one or more of titanium (Ti), barium (Ba), or cerium (Ce) for physical vapor deposition (PVD) that allows pasting to minimize outgassing and control defects during etching of a substrate. The shutter disks incorporate getter materials that are highly selective to reactive gas molecules, including O2, CO, CO2, and water.

Abstract: The present disclosure describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. Compounds of the disclosure have activity as dual modulators of Janus kinase (JAK), alone, or in combination with one or more of an additional mechanism, including a tyrosine kinase, such as TrkA or Syk, and PDE4, and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described herein are methods of treating inflammation, auto-immune diseases, cancer, and other conditions susceptible to inhibition of JAK and PDE4 by administering a compound herein described.

Abstract: Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.

Abstract: The present application relates to a method and an apparatus for training machine learning models, a computer device, and a storage medium. The method includes: acquiring a first training sample set and a second training sample set; performing, based on the first training sample set, multiple rounds of model training, to obtain a first machine learning model; and performing, based on the second training sample set, multiple rounds of model training, to obtain a second machine learning model. At least a part of the first machine learning model has a same structure as at least a part of the second machine learning model, at least a part of model parameters of the second machine learning model is used when the first machine learning model is trained, and at least a part of model parameters of the first machine learning model is used when the second machine learning model is trained.