Patents by Inventor Kangjian ZHANG

Kangjian ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12258408
    Abstract: Provided is an oncolytic virus expressing a PD-1 binding protein, i.e., an oncolytic adenovirus comprising a fusion protein expressing a PD-1 single-chain antibody, wherein the fusion protein has a structure of S-VL-L-VH-Fc, S is an optional signal peptide sequence, VL is the light chain variable region of the PD-1 single-chain antibody, L is a flexible linker, VH is the heavy chain variable region of the PD-1 single-chain antibody and Fc is an immunoglobulin Fc fragment.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: March 25, 2025
    Assignee: SHANGHAI YUANSONG BIOTECHNOLOGY CO. LTD.
    Inventors: Kangjian Zhang, Xianlong Fang, Jinfa Gu, Xinyuan Liu
  • Publication number: 20220064670
    Abstract: Provided is an oncolytic virus expressing interferon. Specifically provided is an oncolytic adenovirus comprising a fusion protein expressing interferon, said oncolytic virus being capable of effectively suppressing tumors in vitro and in vivo.
    Type: Application
    Filed: December 24, 2019
    Publication date: March 3, 2022
    Applicant: SHANGHAI YUANSONG BIOTECHNOLOGY CO. LTD.
    Inventors: Kangjian ZHANG, Xianlong FANG, Jinfa GU, Xinyuan LIU
  • Publication number: 20210403564
    Abstract: Provided is an oncolytic virus expressing a PD-1 binding protein, i.e., an oncolytic adenovirus comprising a fusion protein expressing a PD-1 single-chain antibody.
    Type: Application
    Filed: October 24, 2019
    Publication date: December 30, 2021
    Applicant: SHANGHAI YUANSONG BIOTECHNOLOGY CO. LTD.
    Inventors: Kangjian ZHANG, Xianlong FANG, Jinfa GU, Xinyuan LIU