Abstract: A first venous rhythm of a patient is detected above a venous insertion site when a venous catheter connected to an infusion set is inserted into the venous insertion site and, concurrently with the first venous rhythm, a second venous rhythm is detected at a location remote from the venous insertion site. An irregularity between the first and second venous rhythms is identified, and a failure of the venous catheter is determined based on the identified irregularity satisfying a irregularity threshold. An alarm may be provided on detecting the irregularity or the failure of the venous catheter.

Abstract: A system for measuring drip rate may include a drip chamber device comprising an elongated body including an inner surface defining a chamber, and a drip rate measurement device. The drip chamber may be fluidly coupled to a container containing an IV fluid configured to drip droplets of the IV fluid into the chamber. The drip rate measurement device may include a housing configured to be mounted to the elongated body of the drip chamber, and a load cell transducer mounted in the elongated body and extending into the chamber. The load cell transducer may be configured to measure a weight of the droplets of the IV fluid and convert the weight into an electrical signal. The drip rate measurement device may further include a controller electrically coupled to the load cell transducer to process the electrical signal and output at least one parameter associated with the IV fluid.

Abstract: Check valves are described herein. A check valve includes an inlet body, an outlet body, a valve body, a valve member, and a wiping extension. The inlet body defines an inlet portion. The outlet body defines an outlet portion. The valve body is coupled between the inlet bod and the outlet body. The valve body defines a valve cavity. The valve cavity is in fluid communication with the inlet portion and the outlet portion. The valve member is disposed within the valve cavity. The valve member is configured to permit flow from the inlet portion to the outlet portion and prevent flow from the outlet portion to the inlet portion. The wiping extension extends from the valve body toward the valve member. The wiping extension is movable relative to the valve member to dislodge particulate from the valve member.

Abstract: A pressure detection system includes a body having an internal chamber with input and output ports and a flexible membrane fluidically sealed to an exposed opening of the chamber to prevent a fluid passing through the chamber from passing through the exposed opening. The membrane is configured to change shape responsive to an increase in pressure caused by the fluid within the chamber satisfying a predetermined threshold. In some implementations, the membrane includes or is part of an identification mechanism which moves outwards, away from the chamber, as the pressure increases to indicate the pressure increase. In some implementations, the identification mechanism includes markings on the surface of the membrane, and an image sensing device reads the markings, and provides an indication of a current pressure associated with the fluid in the chamber based on a variation in the markings from a default state.

Abstract: Fluid connector systems that can include first and second valve assemblies that are couplable together to form a fluid pathway through the fluid connector system when the first and second valve assemblies are coupled together, and can resist fluid flow through each of the first and second valve assemblies when the first and second valve assemblies are separated from each other, where the first and second valve assemblies can include a compressible element or post positioned within a channel and configured resist fluid flow through the respective first or second valve assembly in a first position and to reduce the resistance to fluid flow through the first or second valve assembly in a second position, and the first and second valve assemblies including a sleeve and one or more arm configured to engage each other to form a snap fitting feature that can resist separation therebetween.

Abstract: Fluid clamps are described herein. A fluid clamp includes a clamp body and a rotating body. The clamp body includes a first and second valve element. Each valve element includes a valve extension portion and a valve end portion extending from the valve extension portion. The first and second valve elements are disposed opposite to each other to allow a tubing to pass between the first and second valve elements. The rotating body is rotatably coupled to the clamp body. The rotation of the rotating body moves the valve end portion of at least one of the first and second valve elements to adjust a flow rate through the tubing.

Abstract: A needle-free connector assembly is provided that includes a main housing coupled to an indicator housing. A plunger is coupled to a bellows disposed in the main housing. An inlet port is disposed at an upstream end of the indicator housing and an outlet port is disposed at a downstream end of the main housing, with a valve disposed within the indicator housing and adjacent the inlet port. A switch member is slidingly disposed in the main housing, wherein the needle-free connector assembly provides both flow regulation and pressure indication when the switch member is in a downstream position and only pressure indication when the switch member is in an upstream position. Infusion sets and methods of operating a needle-free connector are also provided.

Abstract: Check valves are described herein. A check valve includes an inlet body, an outlet body, a valve body, a valve member, and a wiping extension. The inlet body defines an inlet portion. The outlet body defines an outlet portion. The valve body is coupled between the inlet bod and the outlet body. The valve body defines a valve cavity. The valve cavity is in fluid communication with the inlet portion and the outlet portion. The valve member is disposed within the valve cavity. The valve member is configured to permit flow from the inlet portion to the outlet portion and prevent flow from the outlet portion to the inlet portion. The wiping extension extends from the valve body toward the valve member. The wiping extension is movable relative to the valve member to dislodge particulate from the valve member.

Abstract: A connector for coupling a container carrying a medical fluid to a vascular access device may include a housing comprising and inner surface defining an internal chamber comprising a fluid channel disposed in the internal chamber. The fluid channel may include a pair of oppositely positioned cutouts. The connector may further include a slider disposed and supported in the internal chamber and having an internal compartment and an aperture through inner walls of the internal compartment. The slider may be reciprocally movable between (i) a first position, where the aperture of the slider is axially aligned with the pair of cutouts to allow the medical fluid to flow through the outlet, and (ii) a second position where the aperture of the slider is not aligned with the pair of cutouts and the inner walls of the slider blocks fluid connection between the slider and the fluid channel.

Abstract: A drip chamber device may include a housing including an inlet and an outlet disposed downstream of the inlet, and a chamber defined by an inner circumferential surface of the housing. The chamber may fluidly connect the inlet with the outlet. A valve member may be disposed in the chamber to move between (i) a closed state where fluid communication between the inlet and the chamber is blocked, and (ii) an open state where fluid communication between the inlet and the chamber is not blocked, based on a level of fluid within the chamber.

Abstract: A system for measuring drip rate may include a drip chamber device comprising an elongated body including an inner surface defining a chamber, and a drip rate measurement device. The drip chamber may be fluidly coupled to a container containing an IV fluid configured to drip droplets of the IV fluid into the chamber. The drip rate measurement device may include a housing configured to be mounted to the elongated body of the drip chamber, and a load cell transducer mounted in the elongated body and extending into the chamber. The load cell transducer may be configured to measure a weight of the droplets of the IV fluid and convert the weight into an electrical signal. The drip rate measurement device may further include a controller electrically coupled to the load cell transducer to process the electrical signal and output at least one parameter associated with the IV fluid.

Abstract: The invention relates to devices, systems, and methods for mixing one or more solutions to generate a recharge solution having specified concentrations of a sodium salt and acid for recharging and disinfecting zirconium phosphate in reusable sorbent modules. The devices, systems, and methods can generate a recharge solution by a sorbent recharger that is introduced through the sorbent module to recharge and to disinfect the zirconium phosphate.

Abstract: A PET-MRI apparatus includes a patient support assembly having a cradle to accommodate a subject, a carriage assembly to attach to the cradle and cause the cradle to selectively travel, and a rear bridge to receive the cradle and carriage. The patient support assembly also includes a front bridge to receive the cradle and carriage assembly and provide for translation therealong, with the front bridge including a first section and a second section that is spaced apart from the first section to form a gap in the front bridge between the first section and the second section in an area adjacent a PET detector array of the PET-MRI apparatus. The front and rear bridges include an anti-tip rail assembly to interact with the cradle and the carriage assembly so as to prevent tipping thereof when traversing over the gap between the first and second sections of the front bridge.

Abstract: The invention relates to devices, systems, and methods for mixing one or more solutions to generate a recharge solution having specified concentrations of a sodium salt and acid for recharging and disinfecting zirconium phosphate in reusable sorbent modules. The devices, systems, and methods can generate a recharge solution by a sorbent recharger that is introduced through the sorbent module to recharge and to disinfect the zirconium phosphate.

Abstract: Systems and methods for managing effluent from recharging zirconium phosphate and/or zirconium oxide are provided. The systems and methods control the pH of the zirconium phosphate and zirconium oxide effluent to allow for safe disposal. The systems and methods provide for management of the recharger effluent pH while recharging zirconium phosphate and zirconium oxide either independently or concurrently.

Abstract: Control logic and processes for monitoring and controlling sorbent rechargers are presented. The control logic and processes use control systems to monitor the rechargers for performance problems and to control the recharging process. Various sensors in communication with the control systems are provided to ensure proper operation.

Abstract: Systems and methods for recharging zirconium phosphate and zirconium oxide in reusable sorbent modules are provided. The systems and methods provide for recharging any combination of zirconium phosphate and/or zirconium oxide sorbent modules. The systems and methods also provide for linkage of multiple rechargers for sharing of infrastructure.