Patents by Inventor Kanut LAOHARAWEE

Kanut LAOHARAWEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEUROLOGIC DISEASE
    Publication number: 20230330195
    Abstract: Nucleases and methods of using these nucleases for inserting a sequence encoding a therapeutic IDUA or IDS protein such as an enzyme into a cell, thereby providing proteins or cell therapeutics for treatment and/or prevention of MPS I or MPS II disease.
    Type: Application
    Filed: October 24, 2022
    Publication date: October 19, 2023
    Inventors: Russell DeKelver, R. Scott McIvor, Li Ou, Thomas Wechsler, Chester B. Whitley, Kanut Laoharawee
  • GENOME EDITED PRIMARY B CELL AND METHODS OF MAKING AND USING
    Publication number: 20220168342
    Abstract: Genonie-edited primary B cells, methods of making genome-edited primary B cells, a therapeutic cassette that can be introduced into primary B cells, and methods of using the genome-edited primary B cells and the therapeutic cassette.
    Type: Application
    Filed: September 12, 2017
    Publication date: June 2, 2022
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Branden S. MORIARITY, John HUNZEKER, Matthew JOHNSON, Kanut LAOHARAWEE
  • METHOD FOR IMPROVING NEUROLOGICAL FUNCTION IN MPSI AND MPSII AND OTHER NEUROLOGICAL DISORDERS
    Publication number: 20220096659
    Abstract: A method to prevent, inhibit or treat one or more neurological symptoms associated with a central nervous system disorder, e.g. MPSI or MPSII by, for example, intrathecally, intracerebroventricularly or intravenously administering a rAAV encoding a gene product associated with the disease, e.g., administering to an adult mammal in which the gene product is absent, defective or present at a reduced level relative to a mammal without the disease.
    Type: Application
    Filed: October 22, 2021
    Publication date: March 31, 2022
    Inventors: Kanut Laoharawee, Kelly M. Podetz-Pedersen, Karen Kozarsky, R. Scott McIvor, Lalitha R. Belur
  • GENOME ENGINEERING PRIMARY MONOCYTES
    Publication number: 20210254068
    Abstract: The present disclosure relates generally to methods and tools for engineering a genome of a mammalian monocyte. In particular, the present disclosure relates to mammalian monocytes having at least one altered locus, and reagents for production thereof.
    Type: Application
    Filed: June 19, 2019
    Publication date: August 19, 2021
    Applicant: Regents of the University of Minnesota
    Inventors: Branden S. MORIARITY, Kanut LAOHARAWEE, Matthew J. JOHNSON
  • METHOD FOR IMPROVING NEUROLOGICAL FUNCTION IN MPSI AND MPSII AND OTHER NEUROLOGICAL DISORDERS
    Publication number: 20190269799
    Abstract: A method to prevent, inhibit or treat one or more neurological symptoms associated with a central nervous system disorder, e.g. MPSI or MPSII by, for example, intrathecally, intracerebroventricularly or intravenously administering a rAAV encoding gene product associated with the disease, e.g., administering to an adult mammal in which the gene product is absent, defective or present at a reduced level relative to a mammal without the disease.
    Type: Application
    Filed: November 15, 2017
    Publication date: September 5, 2019
    Inventors: Kanut LAOHARAWEE, Kelly M. PODETZ-PEDERSEN, Karen KOZARSKY, R. Scott MCIVOR, Lalitha R. BELUR